Red Guava Juice (Psidium guajava L.) Reduce Oxidative Stress of Toll Gate Collector

https://doi.org/10.22146/agritech.23030

Riva Mustika Anugrah(1*), Sugeng Maryanto(2), Kusmiyati Tjahjono(3), Martha Irene Kartasurya(4)

(1) Nutritional Science, Faculty of Health, Ngudi Waluyo University, Jl. Diponegoro No. 186, Ungaran District
(2) Nutritional Science, Faculty of Health, Ngudi Waluyo University, Jl. Diponegoro No. 186, Ungaran District
(3) Biochemistry Faculty of Medicine, Diponegoro University, Jl. Prof. H. Soedarto, S. H., Tembalang, Semarang
(4) Public Health Nutrition Department, Faculty of Public Health, Diponegoro University Indonesia, Jl. Prof. H. Soedarto, S. H., Tembalang, Semarang
(*) Corresponding Author

Abstract


Exposure to air pollution can increase the occurrence of oxidative stress. Research showed that guava can reduce oxidative stress in Sprague Dawley rats. This experiment investigated the effect of red guava juice on oxidative stress in toll collectors. The subjects were 20 toll collectors in the treatment group and 20 in the control group. The treatment group received 250 mL red guava juice for 21 days while the controls did not receive anything. Malondialdehyde (MDA) was measured with thiobarbituric acid (TBA) reaction, food consumption was measured by 3×24 hours’ recall. The data were analyzed by paired t-test, Wilcoxon test, independent t-test, Mann Whitney test, and general linear model. The results showed that the effect of red guava juice on the MDA level was significant in the treatment group (p<0.05). A multivariate analysis showed that the effect of red guava juice to MDA level was significant after controlled by age, carbohydrate intake and initial conditions (p<0.05). Red guava juices of 250 mL for 21 days could reduce malondialdehyde (MDA) levels of toll collectors.

Keywords


Red guava juice; malondialdehyde; toll collector; oxidative stress

Full Text:

PDF


References

Akila, V. Prashant, Harishchandra, H., D’souza, V., D’souza, Benedicta. (2007). Age Related Changes In Lipid eroxidation and Atioxidant in Elderly People . Indian Journal of Clinical Biochemistry, 22(1), 131-134.

Arbak, P., Yavuz, O., Bukan, N., Balbay, O., Ulger, F., Annakkaya, A. N. (2004). Serum oxidant and antioxidant levels in diesel exposed toll collectors. J Occup Health, 46(4), 281-88. http://doi:10.1539/joh.46.281

Campen, M. J. and Lund, A. M. R. (2013). Mechanism Linking Traffic Related air Pollution and Atherosclerosis. Natl Institue Health, 18(2), 150-160. http://doi:10.1097/MCP 0B013e32834f210a

Central Java Environment Agency. (2015). Report of Air Quality Monitoring in 35 District/City, 45-48.

Chao, H., Wu, P., Lo, D., Wu, W., Wu, M. (2013). Effect of guava (Psidium guajava Linn.) fruit water extract on lipid peroxidation and serum lipid profiles of streptozotocin-nicotinamide induced diabetic rats. Moleculs. 7(32):2299-2305. http://doi:10.5897/AJPP2013.3698

Eom SY, Yim DH, Moon SI, Youn JW, Kwon HJ, Oh HC, Yang JJ, Park SK, Yoo KY, Kim HS, Lee KS, Chang SH, Kim YD, Kang JW, Kim H (2013). Polycyclic Aromatic Hydrocarbon-induced Oxidative Stress, Antioxidant Capacity, and the Risk of Lung Cancer : International Journal of Cancer Research and Treatment ,3089-3097.

Elmouttaleb, A. T. A., Mostafa, U. E. (2012). Effect of Tomato and Guava juices on Oxidative Stress in Rats after Strenuous Exercise. JJBS, 5(3), 167-174. http://doi: 10.3109/13880209.2012.688057

Guéraud, F. (2010). Lipid Peroxidation Originating α,β-unsaturated Aldehydes and Their Metabolites as Biomarkers. In Biomarkers for Antioxidant Defense and Oxidative Damage:Principles and Practical Applications, Iowa: Wiley-Blackwell, 117-121.

Hermsdorff HH, Barbosa KB, Volp AC, Puchau B, Bressan J, Zulet MÁ, Martínez JA.(2 012). Vitamin C and fibre consumption from fruits and vegetables improves oxidative stress markers in healthy young adults. British Journal of Nutrition (107), 119-127. http://doi:10.1017/S0007114511004235

Kusminingrum, N. and Gunawan, G. (2010). Effects air pollution in Urban Road Vehicle Java and Bali. Road and Bridge Research and Development Centre.

Lodovici, M. and Bigagli, E. (2011). Oxidative Stress and Air Pollution Exposure. Journal of Toxicology. Volume 2011 9 pages http://doi:10.1155/2011/487074

Moreira, M. A., Nascimento, M. A., Bozzo, T. A., Cintra, A., Da Silva, S. M., Dalboni, M. A.(2014). Ascorbic acid reduces gentamicin-induced nephrotoxicity in rats through the control of reactive oxygen species. Clin Nutr., 33(2), 296-301. https://doi: 10.1016/j.clnu.2013.05.005

Murini (2014). The effect of red guava fruit juice (Psidium guajava L.) on lipid profile and atherosclerosis in Rats. Faculty of Medicine Gajah Mada University.

Norshazila S, Syed ZI, Musthapa SK, Aisyah MR, Kamarul RK. (2010). Antioxidant levels and activities of selected seeds of Malaysian Tropical Juices. Mal J Nutr 16(1): 149-159

Pacier, C. and Martirosyan, D. M. (2015). Vitamin C : optimal dosage , supplementation and use in disease prevention. Funct Foods Heal Dis, 5(3), 89-107.

Padayatty SJ1, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M. (2003). Vitamin C as an antioxidant: evaluation of Its role in disease prevention. J Am Coll Nutr 22(1), 18-35. https://doi:10.1080/07315724.

Romieu, I., Kunzli, N., Sunyer, J. (2008). Air pollution, oxidative stress and dietary supplementation: a review. Eur Respi J, 31(1):179-196. doi: 10.1183/09031936.00128106.

Sareen, S., Gropper, J. L. S., Groff, J. L. (2009). Advance Nutrition and Human Metabolism .Chapter 9, 312-320. 5th ed. Canada: Wardsworth Cengage Learning

Sudjarwo SA.(2011). Mechanisms of endothelial cell protection by quercetin in hypercholesterolemia. Research in Pharmaceutical Biotechnology Vol. 3(9), pp. 123-127,

Zabidah AA, Kong KW and Amin I (2011). Antioxidant properties of tropical juices and their effects on in vitro hemoglobin and low density lipoprotein ( LDL ) oxidations. International Food Research Journal, (18), 549-556.

Zhang YJ, Gan RY, Li S, Zhou Y, Li AN, Xu DP, Li HB (2015). Review Antioxidant Phytochemical for the prevention and Treatment of Chronic Disease. MDPI Molecules. Nop 27;20(12):21138-56. doi: 10.3390/molecules201219753



DOI: https://doi.org/10.22146/agritech.23030

Article Metrics

Abstract views : 3385 | views : 2474

Refbacks

  • There are currently no refbacks.




Copyright (c) 2019 Riva Mustika Anugrah, Sugeng Maryanto, Kusmiyati Tjahjono, Martha Irene Kartasurya

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

agriTECH has been Indexed by:


agriTECH (print ISSN 0216-0455; online ISSN 2527-3825) is published by Faculty of Agricultural Technology, Universitas Gadjah Mada in colaboration with Indonesian Association of Food Technologies.


website statisticsView My Stats