Microencapsulation of Crude Folic Acid Extract from Chayote (Sechium edule Jacq. Swartz) with Ionic Gelation Method

https://doi.org/10.22146/ifnp.32520

Johana Novita Paulina Purba(1*), Herla Rusmarilin(2), Zulkifli Lubis(3)

(1) Department of Food Science, Faculty of Agricultural, Universitas Sumatera Utara, Medan
(2) Department of Food Science, Faculty of Agricultural, Institut Pertanian Bogor, Bogor
(3) Department of Food Science, Universitas of New South Wales, Sydney, Australia
(*) Corresponding Author

Abstract


Chayote is a plant which grow and develop throughout the year, contains of  93 mcg/100g folic acid. The aim of this research was to determine the ratio of sodium alginate with pectin and CaCl2 concentration coating to produce microcapsules of crude folic acid extract. Four phases of study was done, namely the manufacture of folic acid extract, manufacture of microcapsules with ionic gelation, analysis of folic acid content in the microcapsules, and the analysis of folic acid after storage of one week. Folic acid extract was made by maceration using alcohol 70% at pH 6, preparation of the microcapsules was using sodium alginate with pectin and folic acid was analysed using HPLC. Folic acid extract showed antioxidant activity of 98,1% with folic acid of 0,16 mg/kg. Microencapsulation of folic acid extract results showed the highest antioxidant activity was formed in alginate ratio of  70% to 30% pectin and CaCl2 concentration of 0.1 M i.e.  62.77 mg/kg. Folic acid is an antioxidant, highest antioxidant value folic acid was analyzed,  treatment was in alginate ratio of 70% to 30% pectin and CaCl2 concenration at 0.1 M i.e. 3.06 mg/kg, after one week at room temperature is became 2.39 mg/kg.

 


Keywords


Folic acid, chayote, microencapsulation, sodium alginate, pectin

Full Text:

PDF


References

Abror, M. U. S., and Cahyaningrum, S. E. 2015. Pengaruh konsentrasi agen pengikat silang terhadap karakteristik pirasinamid terenkapsulasi. UNESA Journal of Chemistry. 4(1).

Angraini, A. D. 2006. “Potensi propolis lebah madu Trigona sp. sebagai bahan antibakteri”. Skripsi. Program Studi Biokimia, Bogor.

Aslan, L. M. 1999. “Budidaya rumput laut”. Penerbit Kanisius, Yogyakarta.
BPS. 2014. “Produksi Buah-Buahan Menurut Jenis Tanaman 2009-2014”. http: sumut.bps.go.id [9 Desember 2015].

Bender, D. A. 2002. “Introduction to nutrition and metabolism, Third edition”. New York. Taylor Francis: 380-384.

Dwijayanti, R. 2009. “Pemanfaatan natrium alginat sebagai fortifikasi serat dalam pembuatan minuman serbuk effervescent bercita rasa jeruk lemon”. Program Studi Teknologi Hasil Perikanan, Institut Pertanian Bogor, Bogor.

Dwiyitno. 2011. Rumput laut sebagai sumber serat pangan potensial. Squalen. 6 (1): 9-17.

Estiasih, T. and Ahmadi. 2009. “Teknologi pengolahan pangan”. Bumi Aksara, Jakarta.

Faradiba., Hasyim, N. and Zahriati. 2013. Formulasi garanul effervescent ekstrak etanol daun jambu biji (Psidium guajava LINN). Majalah Farmasi dan Farmakologi. 12(12).

Fardiaz, D. 1989. Hidrokoloid. Laboratorium Kimia dan Biokimia Pangan. Antar Universitas Pangan dan Gizi. Institut Pertanian Bogor, Bogor.

Febriyenti., Ben, E. S. and Prima, T. 2013. Formulasi mikrokapsul glikuidon menggunakan penyalut etil selulosa dengan metode emulsifikasi penguapan pelarut. Prosiding Seminar Nasional Perkembangan Terkini Sains Farmasi dan Klinik III. ISSN: 2339-2592.

Fennema, O. R. 1976. “Principles of food sciences”. pp.792 Marcel Dekker, Inc. New York.

Fitriani, N. L. C., Walanda, D. K. and Rahman, N. 2013. Penentuan kadar kalium (K) dan kalsium (Ca) dalam labu siam (Sechium edule) serta pengaruh tempat tumbuhnya. Journal Akad. Kim. 1(4): 174-180.

Gusdinar, T., Singgih, M., Priatni, S., Sukmawati, A. E. and Suciati, T. 2011. Enkapsulasi dan stabilitas pigmen karotenoid dari Neurospora intermedia N-1. Jurnal Manusia Dan Lingkungan. 18 (3): 206-211.

Harbone, J. B. 1988. “The flavonoids, advances in research since 1980”. Chapman and Hall, New York.

Jaya, S., Durance, T. D., and Wang, R. 2010. Physical characterization of drug loaded microcapsules and controlled in vitro release study. The Open Biomaterial Journal. 2:9-17.

Jelvehgari, M., Mobaraki, V. and Montazam, S. H. 2014. Preparation and evaluation of mucoadhesive beads/discs of alginate and algino-pectinate of piroxicam for colon-specific drug delivery via oral route. Jundishapur Journal Nat Pharm Prod. 9(4):1-10.

Joshi, R., Adhikari, S., Patro, B. S., Chattopadhyay, S. and Mukherjee, T. 2001. Free radical scavenging behavior of folic acid: evidence for possible antioxidant activity. Elsivier. Free Radical Biology and Medicine. 30(12):1390–1399.

Juwita, W., Rusmarilin, H. and Yusraini, E. 2014. Pengaruh konsentrasi pektin dan karagenan terhadap mutu permen jely jahe. Jurnal Rekayasa Pangan dan Pertanian. 2(2):42-50.

Lankapalli, S. and Kolapalli, V. 2009. Polyelectrolyte complexes: a review of their applicability in drug delivery technology. Indian Journal Pharmaceutical Science. 7(5): 481-487.

Madziva, H., Kailasapathy, K. and Phillips, M. 2005. Alginate-pectin microcapsules as a potential for folic acid delivery in foods. Journal Microencapsulation 22(4):343-357.

Marliana, S. D., Suryanti, V. and Suyono. 2005. Skrining fitokimia dan analisis kromatografi lapis tipis komponen kimia buah labu siam (Sechium edule Jacq. Swartz.) dalam ekstrak etanol. Biofarmasi. 3(1): 26-31.

Melodita, R. 2011. “Identifikasi pendahuluan senyawa fitokimia dan uji aktivitas antioksidan ekstrak daun cincau hitam dengan perlakuan jenis pelarut”. Skripsi. Fakultas Teknologi Pertanian. Universitas Brawijaya, Malang.

Onayanti, N., R. G. Budji. and Sartini. 2015. “Uji viabilitas probiotik asal saluran pencernaan itik pedaging Anas domesticus yang dienkapsulasi dengan metode cross link”. Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Hasanuddin, Makassar.

Peranginangin, R., A. M. Handayani, D. Fransiska, W. M. Djagal and Supriyadi. 2015. Pengaruh CaCl2 dan alginat terhadap karakteristik analog bulir jeruk dari alginat. Ilmu dan teknologi pangan. JPB Kelautan dan Perikanan. 10(2): 163–172.

Sani, R. N., Nisa, F. C., Andriani, R. D. and Maligan, J. M. 2014. Analisis rendemen dan skrining fitokimia ekstrak etanol mikroalga laut Tetraselmis chuii. Jurnal Pangan dan Agroindustri. 2(2): 121-126.

Sari, F. E., Trisnowati, S. and Mitrowiharjo, S. 2004. Pengaruh kadar CaCl2 dan lama perendaman terhadap umur simpan dan pematangan buah mangga arumanis. Fakultas Pertanian. Universitas Gadjah Mada. Ilmu Pertanian. 11(1): 42-50.

Sari., Ratna., Puspita, D. and Rijal, M. A. S. 2012. Pengaruh perbandingan obat polimer terhadap karakteristik fisik dan pelepasan mikropartikel ketoprofen-kitosan. Pharma Scientia. 1(2).

Seixas, F. L., Turbiani, F. R. B., Salomao, P. G., Souza, R. P. and Gimenes, M. L. 2013. Biofilms composed of alginate and pectin: effect of concentration of crosslinker and plasticizer agents. Chemical Engineering Transactions. 32:1693-1698.

Siswanti, C. A., Roosdiana, A. and Sutrisno. 2013. Optimasi amobilisasi pektinase dari Bacillus subtilis menggunakan ca-alginat-kitosan. Kimia Student Journal. 1(2):194-200.
Syahron, Y. N. 2016. “Enkapsulasi ibuprofen dengan natriumn alginat-pektin menggunakan metode gelasi ionik”. Skripsi. Fakultas Matematika Dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor.

Tan, L. H., Chan, L. W. and Heng, P. W. S. 2009. Alginate/starch composites as wall material to achieve microencapsulation with high oil loading. Informa Heath Care Journal of Microencapsulation. 26(3):263-271.

Tello, F., Cortes, R. N. F., Bustos, F. M., da Silva, V. M., Hubinger, M. D. and Grosso. C. 2015. Alginate and pectin-based particles coated with globular proteins: production, characterization and anti-oxidative properties. Elsivier. Food Hydrocoloids. 43:670-678.

U.S. Department of Agriculture (USDA), Agricultural Research Service. 2008. National Nutrient Database for Standard Reference, Release 21.

Winarno, F. G. 2008. “Kimia pangan dan gizi”. M. Brio Press, Bogor

Yuniati, H. and Almasyhuri. 2002. Kandungan vitamin B6, B9, B12 dan E beberapa jenis daging, telur, ikan dan udang laut di bogor dan sekitarnya. Penel Gizi Makan. 35(1): 78-89.



DOI: https://doi.org/10.22146/ifnp.32520

Article Metrics

Abstract views : 3102 | views : 3613

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Indonesian Food and Nutrition Progress (print ISSN 0854-6177, online ISSN 2597-9388) is published by the Indonesian Association of Food Technologist in collaboration with Department of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada.

Journal of Indonesian Food and Nutrition Progress have been indexed by: 

   

 

This works is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.