An Update of Anticoagulant in Venous Thromboembolism

Abstract

Venous thromboembolism (VTE), comprised of deep vein thrombosis (DVT) and pulmonary embolism (PE), is a result of propagating thrombus formation in the vein due to either hypercoagulability, stasis, or endothelial injury. Recently, this disease warrant global awareness due to its contribution on death and chronic morbidity.Global surveillance has reported the increment of VTE incidences particularly in Asia, although it is still lower than rest of the world. Venous thromboembolism in Asia has a characteristic dominated by female gender, underweight and has main risk factors of cancer and hospitalization. According to IDENTIA, a registry of incidence of deep vein thrombosis in medically ill patient in Indonesia, the incidence of DVT increase parallel with long duration of immobilization, obesity and cancer history.