Carotid Intima Media Thickness as a Predictor for the Severity of Coronary Artery Disease

Abstract

Background: Coronary artery disease is the chief cause of non infection cause of death in the developing country, carotid intima-media thickness evaluation
are used for over three decade to asses atherosclerotic burden, this study aimed to seek correlation between carotid intima-media thickness with coronary artery disease severity.
Methods: This was a cross-sectional study involving 63 patients diagnosed with stable angina pectoris in Haji Adam Malik General Hospital Medan from November 2018 to December 2018. Carotid Doppler USG and Angiography were performed for each patients. Chi-Square test will be performed to analyze correlation between internal carotid intima-media thickness with Gensini score.
Results: From 63 subjects, 23 subjects (82.1%) with internal carotid intimamedia thickness ≥ 0.75mm have Gensini score ≥20 while patients with carotid
intima-media thickness <0.75mm 8 (22.9%) have Gensini score ≥20 (p<0.001). Cut-off point 0.55 mm (Sensitivity: 93.5% and Specificity: 87.5%) was a marker for high Gensini score.
Conclusion: Internal Carotid intima-media thickness with cut-off point 0.55 mm can be used to predict the severity of coronary artery disease measured by Gensini Score in stable coronary artery disease patients.