In Vitro Antiplasmodial Activity and Cytotoxicity of Isolates of Pasak Bumi (Eurycoma longifolia Jack) Root
Eti Nurwening Sholikhah(1*), Mahardika Agus Wijayanti(2), Laela Hayu Nurani(3), Mustofa Mustofa(4)
(1) Departemen Farmakologi & Terapi, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM, Yogyakarta
(2) Departemen Parasitologi, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM, Yogyakarta
(3) Fakultas Farmasi, Universitas Ahmad Dahlan, Yogyakarta
(4) Departemen Farmakologi & Terapi, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM, Yogyakarta
(*) Corresponding Author
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Ang, H. H., Chan, K. L., & Mak, J. W. 1995. In vitro antimalarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates. Planta Med. 61: 177-178. Bedir, E., Abou-Gazar, H., Ngwendson, J. N., & Khan, I. A. 2003. Eurycomaside: A new quassinoid from the roots of Eurycoma longifolia. Chem. Pharm. Bull. 51(11): 1301-1303. Chan, K.L., O’Neill, M.J., Philippson, J.D., Warhurst, D.C., 1986. Plants as sources of antimalarial drugs. Part 3 Eurycoma longifolia. Planta Medica 52: 105-107. Gessler, M.C., Nkunya, M.H.N., Mwasumbi, L.B., Heinrich, M., Tonner, M. 1994. Screening Tanzanian Medical Plants for Antimalarial Activity. Acta-Trop. 55:65-67. Hughes, D., & Mehmet, H. 2003. Cell Proliferation & Apoptosis, BIOS Scientific Publishers Ltd, Oxford, 19-20. Jiwadinda, S., Santisopasri, V., Murakami, A., Hirai, N., & Ohigashi, H. 2001. Quassinoids from Eurycoma longifolia as plant growth inhibitors. Phytochemistry 58:956-962. Jiwadinda, S., Santisopasri, V., Murakami, A., Kawanaka, M., Kawanaka, H., Gasquet, M., Eilas, R., Balansard, G., & Ohigashi, H. 2002. In vitro anti-tumor promoting and anti-parasitic activities of the quassinoids from Eurycoma longifolia, a medicinal plant in Southeast Asia. J. Etnopmarmacol. 82: 55-58. Mardisiswojo, S. & Radjakmangunsudarso. 1975. Cabe puyang warisan nenek moyang. Karya Wreda, Jakarta. Mustofa & Sholikhah, E.N. 2007. Aktivitas antiplasmodium in vitro dan in vivo fraksi yang diperoleh dari ekstrak metanol pasak bumi (Eurycoma. Longifolia Jack) yang secara tradisional digunakan mengobati malaria di Kalimantan Selatan. Majalah Obat Tradisional., 11: 25-30. Mustofa & Qamariah, N. 2004. In vitro antiplasmodial activity and cytotoxicity of aqueous. methanol and chloroform extracts akar pasak bumi (Eurycoma longifolia Jack) traditionally used to treat malaria in South Kalimantan. Medika, 3: 147-152. Ridzuan, M.A.M., Sow, A, Rain A., N., Ilham A., M., Zakiah, I. 2007. Eurycoma longifolia extract-artemisinin combination: parasitemia suppression of Plasmodium yoelii-infected mice. Trop Biomed, 24(1):111-8. Syamsuhidayat, S. S. 1997. Inventarisasi tanaman obat Indonesia IV. Badan Penelitian dan Pengembangan Kesehatan.
DOI: https://doi.org/10.22146/farmaseutik.v14i2.42595
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