Quorum Sensing: Suatu Sistem Komunikasi Bakteri Fitopatogen, Peranannya Pada Proses Infeksi, dan Peluangnya sebagai Basis Pengembangan Strategi Baru dalam Pengendalian Penyakit Tumbuhan
Hadiwiyono Hadiwiyono(1*)
(1) Fakultas Pertanian Universitas Sebelas Maret
(*) Corresponding Author
Abstract
Previously, it is thought that bacterium is an autonomous unicellular organism with no capacity for collective behavior. Now the paradigm has changed since there are communication between intercell bacteria. The phytopathogenic bacteria are able to regulate gene expression which play an important role in infection process in the host plant. The gene expression regulation involves an intercell communication in the population and this is called as quorum sensing (QS). This paper reviews the QS as a communication system of phythopathogenic bacteria, its role in infection process on the host plant, and its opportunity as the basis of novel strategy development on plant disease control.
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Aldon, D., B. Brito, C. Boucher, & S. Genin. 2000. A Bacterial Sensor of Plant Cell Contact Controls the Transcriptional Induction of Ralstonia solanacearum Pathogenicity Genes. EMBO Journal 19: 2304–2314.
Bainton, N.J., P. Stead, S.R. Chhbra, B.W. Bycroft, G.P.C. Salmond, G.S.A.B. Stewart, & P. Williams. 1992. N-(3-Oxohexanoyl)-L homoserine Lactone Regulates Carbapenem Antibiotics Production in Erwinia carotovora. Biochemical Journal 288: 997–1004.
Barnard,A.M.L. & G.P.C. Salmond. 2007. Quorum Sensing in Erwinia Species. Analytical and Bioanalytical Chemistry 387: 415–423.
Bertani, I. & V. Venturi. 2004. Regulation of the Nacyl Homoserine Lactone-dependent Quorumsensing System in Rhizosphere Pseudomonas putida WCS358 and Cross-talk with the Stationaryphase RpoS Sigma Factor and the Global Regulator GacA. Applied and Environmental Microbiology 70: 5493–5502.
Brito,B., D. Aldon, P. Barberis, C. Boucher, & S. Genin. 2002. A Signal Transfer System through Three Compartments Transducers the Plant Cell Contact-dependent Signal Controlling Ralstonia solanacearum hrp Genes. Molecular Plant Microbe Interactions 15: 109–119.
Bauer, W.D. & U. Mathesius. 2004. Plant Responses to Bacterial Quorum Sensing Signals. Current Opinion in Plant Biology 7: 429–433.
Cao, J.G. & E.A. Meighen. 1989. Purification and Structural Identification of an Autoinducer for the Luminescence System of Vibrio harveyi. Journal of Biological Chemistry 264: 21670–21676.
Chen, C.N., C.J. Chen, C.T. Liao, & C.Y. Lee. 2009. AProbableAculeacinAacylase from the Ralstonia solanacearum GMI1000 is N-acyl-homoserine Lactone Acylase with Quorum quenching Activity. BMC Microbiology 9: 89.
Chhabra, S.R., C. Hart, D.S.W. Hooi, M. Daykin, P. Williams, G. Telford, D.I. Pritchard, & B.W. Bycroft. 2003. Synthetic Analogues of the Bacterial Signal (Quorum Sensing)Molecule N-(3-oxododecanoyl)-L-homoserine Lactone as Immune Modulators. Journal of Medicinal Chemistry 46: 97–104.
Christophersen, P. Steinberg, S. Kjelleberg, & M. Givskov. 2000. How Delisea pulchra Furanones Affect Quorum Sensing and Swarming Motility in Serratia liquefaciens MG1. Microbiology 12: 3237–3244.
Clough, S.J., A.B. Flavier, M.A. Schell, & T.P. Denny. 1997. Differential Expression of Virulence Genes and Motility in Ralstonia (Pseudomonas) solanacearum During Exponential Growth. Applied and Environmental Microbiology 63: 844–850.
Cui, X & R. Harling. 2005. N-acyl-homoserine Lactone-mediated Quorum Sensing Blockage, a Novel Strategy for Attenuating Pathogenicity of Gram-negative Bacterial Plant Pathogens. European Journal of Plant Pathology 111: 327–339.
Cunnac, S., C. Boucher & S. Genin. 2004. Characterization of the Cis-acting Regulatory Element Controlling HrpB-mediated Activation of the Type III Secretion System and Effector Genes in Ralstonia solanacearum. Journal of Bacteriology 186: 2309–2318.
Czajkowski, R. & S. Jafra. 2009. Quenching of Acyl-homoserine Lactone-dependent Quorum Sensing by Enzymatic Disruption of Signal Molecules. Acta Biochimica Polonica 56: 1–16.
de Kievat, T.R. & B.H. Igleswski. 2000. Bacterial Quorum Sensing in Pathogenic Relationship. Infection and Immunity 68: 4839–4849.
Defoirdt, T., C.M. Miyamoto, T.K. Wood, E.A. Meighen, P. Sorgeloos, W. Verstraete, & P. Bossier, 2007. The Natural Furanone (5Z)-4- bromo-5-(bromomethylene)-3-butyl-2(5H)- furanone Disrupts Quorum Sensing-regulated Gene Expression in Vibrio harveyi by Decreasing the DNA-binding Activity of the Transcriptional Regulator Protein luxR. Environmental Microbiology 9: 2486–2495.
Delaspre, F., C.G. Nieto Pen alver, O. Saurel, P. Kiefer, E. Gras, A. Milon, C. Boucher, S. Genin, & J.A. Vorholt. 2007. The Ralstonia solanacearum Pathogenicity Regulator HrpB Induces 3 hydroxyoxindole Synthesis. PNAS 104: 15870–15875.
Dow, J.M., L. Crossman, K. Findlay, Y.Q. He, J.X. Feng, & J.L. Tang. 2003. Biofilm Dispersal in Xanthomonas campestris is Controlled by Cell-cell Signaling and is Required for Full Virulence to Plants. PNAS 100: 10995–11000.
Eberl, L. 1999. N-acyl Homoserinelactonemediated Gene Regulation in Gram-negative Bacteria. Systematic and Applied Microbiology 22: 493–506.
Faure, D. & Y. Dessaux. 2007. Quorum Sensing as a Target for Developing Control Strategies for the Plant Pathogen Pectobacterium. European Journal of Plant Pathology 119: 353–365.
Fray, R.G., J.P. Throup, M. Daykin, A. Wallace, P. Williams, G.S.A.B. Stewart, & D. Grierson. 1999. Plants Genetically Modified to Produce Nacylhomocerine Lactones Communicate with Bacteria. Nature Biotechnology 17: 1017–1020.
Fuqua, W.C., & S.C. Winans. 1994. A LuxR-LuxI Type Regulatory System Activates AgrobacteriumTi Plasmid Conjugal Transfer in the Presence of a Plant Tumor Metabolite. Journal of Bacteriology 176: 2796–2806.
Genin, S. & C. Boucher. 2004. Lessons Learned from the Genome Analysis of Ralstonia solanacearum. Annual Review of Phytopathology 42: 107–134.
Geske, G.D., J.C.O. Neill, & H.E. Blackwell. 2008. Expanding Dialogues: From Natural Autoinducers to Non-natural Analogues that Modulate Quorum Sensing in Gram-negative Bacteria. Chemical Society Reviews 37: 1432–447.
Hentzer, M., K. Riedel, T.B. Rasmussen, A. Heydorn, J.B.Andersen,M.R. Parsek, S.A. Rice, L. Eberl, S. Molin, & N. Hoiby. 2002. Inhibition of Quorum Sensing in Pseudomonas aeruginosa Biofilm Bacteria by a Halogenated Furanone Compound. Microbiology 148: 87–102.
Hentzer, M., H. Wu, J.B. Andersen, K. Riedel, T.B. Rasmussen, N. Bagge, N. Kumar, M.A. SchembriMA, Z. Song Z, & P. Kristoffersen. 2003. Attenuation of Pseudomonas aeruginosa Virulence by Quorum Sensing Inhibitors. EMBO Journal 22: 3803–3815.
Hayward, A.C. 2000. Ralstonia solanacearum, p. 32–42. In J. Lederberg (ed.), Encyclopedia of Microbiology (Vol. 4.).Academic Press, San Diego, California. Hughes, D.T. & V. Sperandio. 2008. Inter-kingdom Signalling: Communication between Bacteria and their Hosts. Nature Reviews Microbiology 6: 111– 120.
Janssens, J.C., S.C. de Keersmaecker, D.E. de Vos, & J. Vanderleyden. 2008. Small Molecules for Interference with Cell-cell-communication Systems in Gram-negative Bacteria. Current Medicinal Chemistry 15: 2144–2156.
Koutsoudis, M.D., D., Tsaltas, T.D. Minogue, & S.B. von Bodman. 2006. Quorum-sensing Regulation Governs Bacterial Adhesion, Biofilm Development, and Host Colonization in Pantoea stewartii subspecies stewartii. PNAS 103: 5983–5988.
Lazazzera, B.A. 2001. The Intracellular Function of Extracellular Signaling Peptides. Peptides 22: 1519–1527.
Li, P. L. & S. K. Farrand. 2000. The Replicator of the Nopaline-type Ti Plasmid pTiC58 is a Member of the repABC Family and is Influenced by the TraR-dependent Quorum-sensing Regulatory System. Journal of Bacteriology 182: 179–188.
Mathesius, U., S. Mulders, M. Gao, M. Teplitski, G.B. Caetano-Anolles, B.G. Rolfe, & W.D. Bauer. 2003. Extensive and Specific Responses of a Eukaryote to Bacterial Quorum Sensing Signals. PNAS 100: 1444–1449.
Molina, L., C. Florica, M. Laurent, R. Cornelia, D. Brion, & D. Genevieve. 2003. Degradation of Pathogen Quorum-sensing Molecules by Soil Bacteria: a Preventive and Curative Biological Control Mechanism. FEMS Microbiology Ecology 45: 71–81.
Nasser,W. & S. Reverchon. 2007. New Insights into the Regulatory Mechanisms of the LuxR Family of Quorum Sensing Regulators. Analytical and Bioanalytical Chemistry 387: 381–390.
Nealson, K.H. & J.W. Hastings. 1979. Bacterial Bioluminescence: its Control and Ecological Significance. Microbiological Reviews 43: 496–518.
Occhialini, A., S. Cunnac., N. Reymond, S. Genin, & C. Boucher. 2005. Genome-wide Analysis of Gene Expression in Ralstonia solanacearum Reveals that the hrpB Gene Acts as a Regulatory Switch Controlling Multiple Virulence Pathways. Molecular PlantMicrobe Interactions 18: 938–949.
Pappas, K.M. & S.C. Winans. 2003. A LuxR-type Regulator from Agrobacterium tumefaciens Elevates Ti Plasmid Copy Number by Activating Transcription of Plasmid Replication Genes. Molecular Microbiology 48: 1059–1073.
Persson, T., M. Givskov, & J. Nielsen. 2005. Quorum Sensing Inhibition: Targeting Chemical Communication in Gram-negative Bacteria. Current Medicinal Chemistry 12: 3103–3115.
Pesci, E.C., J.B.J. Milbank, J.P. Pearson, S. McKnight, A.S. Kende, E.P. Greenberg, & B.H. Iglewski. 1999. Quinolone Signaling in the Cell-tocell Communication System of Pseudomonas aeruginosa. PNAS 96: 11229–11234.
Quinones, B., G. Dulla. & S.E. Lindow. 2005. Quorum Sensing Regulates Exopolysaccharide Production, Motility, and Virulence in Pseudomonas syringae. Molecular Plant Microbe Interactions 18: 682–693.
Salanoubat,M., S. Genin, F.Artiguenave, J. Gouzy, S. Mangenot, M. Ariat, A. Billault, P. Brottier, J.P. Camus, L. Cattolico, M. Chandler, N. Choisene, S. Claudel-Renard, N. Cunnac, C. Gaspin, M. Lavie, A. Molsan, C. Robert, W. Saurin, T. Schlex, P. Siguier, P. Thebault, M. Whalen, P. Wincker, M. Levy, J. Weissenbach, & C.A. Boucher. 2002. Genome Sequence of the Plant Pathogen Ralstonia solanacearum. Nature 415: 497–502.
Schell, M.A. 2000. Control of Virulence and Pathogenicity Genes of Ralstonia solanacearum by an Elaborate Sensory Network. Annual Review of Phytopathology 38: 263–292.
SotoM.J., J. Sanjuan, & J. Olivares. 2006. Rhizobia and Plant-pathogenic Bacteria: Common Infection Weapons. Microbiology 152: 3167–3174.
Smith, D., J.H. Wang , J.E. Swatton, P. Davenport, B. Price, H.Mikkelsen, H. Stickland, K. Nishikawa, N. Gardiol, D.R. Spring, & M. Welch. 2006. Variations on a Theme: Diverse N-acyl Homoserine Lactone-mediated Quorum SensingMechanisms in Gram-negative Bacteria. Science Progress 89: 167–211.
Swift, S, J.A. Downie, N.A. Whitehead, A.M.Barnard, G.P. Salmond, & P. Williams. 2001. Quorum Sensing as a Population-density-dependent Determinant of Bacterial Physiology. Advances in Microbial Physiology 45: 199–270.
Turner, M., A. Jauneau, S. Genin, M.J. Tavella, F. Vailleau, L. Gentzbittel, & M.F. Jardinaud. 2009. Dissection of Bacterial Wilt on Medicago truncatula Revealed Two Type III Secretion System Effectors Acting on Root Infection Process and Disease Development. Plant Physiology 150: 1713–1722.
Uroz, S., P. Oger, S.R. Chhabra, M. Camara, P. Williams, & Y. Dessaux. 2007. N-acyl Homoserine Lactones are Degraded via an Amidolytic Activity in Comamonas sp. strain D1. Archives of Microbiology 187: 249–256.
von Bodman, S.B., W.D. Bauer, & D.L. Coplin. 2003. Quorumsensing in Plant-pathogenic Bacteria. Annual Review of Phytopathology 41: 455–482.
Wei, H.L. & L.Q. Zhang. 2006. Quorum-sensing System Influences Root Colonization and Biological Control Ability in Pseudomonas fluorescens 2P24. Antonie Van Leeuwenhoek 89: 267–280.
White, C.E. & S.C. Winans. 2007. Cell-cell Communication in the Plant Pathogen Agrobacterium tumefaciens. Philosophical Transactions of the Royal Society London. B. Biological Sciences 362: 1135–1148.
White, C.E., & T.M. Finan. 2009. Quorum Quenching in Agrobacterium tumefaciens: Chance or Necessity? Journal of Bacteriology 191: 1123–1125.
Whitehead, N.A, J.T. Byers, P. Commander, M.J.Corbett, S.J. Coulthurst, L. Everson, A.K.P. Harris, C.L. Pemberton, N.J.L. Simpson & H. Slater. 2002. The Regulation of Virulence in Phytopathogenic Erwinia species: Quorum Sensing, Antibiotics and Ecological Considerations. Antonie van Leeuwenhoek 81: 223–231.
Williams, P. 2007. Quorum sensing, Communication and Cross-kingdom Signalling in the Bacterial World. Microbiology 153: 3923–3938.
Williams, P., K.Winzer ,W.C. Chan, &M. Camara. 2007. Look Who’s Talking: Communication and Quorum Sensing in the Bacterial World. Philosophical Transactions of the Royal Society London. B. Biological Sciences 362: 1119–1134.
Winson, M.K., M. Camara, A. Latifi, M. Foglino, S.R. Chhabra,M. Daykin, V. Chapon, B.W. Bycroft, & G.P.C. Salmond. 1995.Multiple Quorum Sensing Modulons Interactively Regulate Virulence and Secondary Metabolism in Pseudomonas aeruginosa: Identification of the Signal Molecules N-butanoyl-Lhomoserine Lactone and N-hexanoyl-L-homoserine Lactone. PNAS 92: 9427–9431.
Yates, E.A., B. Philipp, C. Buckley, S. Atkinson, S.R. Chhabra, R.E. Sockett, M. Goldner, Y. Dessaux, M. Camara, H. Smith, & P. Williams. 2002. N-Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-dependentManner During Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infection and Immunity 70: 5635–5646.
Zhang, Z. & L.S. Pierson. 2008.ASecond Quorumsensing System Regulates Cell Surface Properties but not Phenazine Antibiotic Production in Pseudomonas aureofaciens. Chemical Society Reviews 37: 1432–1447.
DOI: https://doi.org/10.22146/jpti.11765
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