Traditional Medicinal Plants for the Prevention and Treatment of Hypertension: A Literature Review
Athika Reza Febyanesti(1*), Bagoes Widjanarko(2), Zahroh Shaluhiyah(3)
(1) Master of Health Promotion, Faculty of Public Health, Diponegoro University, Semarang
(2) Faculty of Public Health, Diponegoro University, Semarang
(3) Faculty of Public Health, Diponegoro University, Semarang
(*) Corresponding Author
Abstract
Background: Hypertension is described as a disease that has a high prevalence in Indonesia. If it is not appropriately treated, it will cause advanced diseases such as stroke, heart failure, and kidney damage. Therefore, it is necessary to prevent and give early treatment, one of which is through alternative routine consumption of herbal medicines.
Objectives: This study aims to find out the benefits of herbal medicine for people with hypertension.
Methods: The method used in this research is a literature review. It is carried out in several stages by analyzing relevant previous pieces of literature using the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) flowchart that illustrates the flow of information through the different phases of a systematic review.
Results: A total of 11 reviewed articles show that various herbal plants were obtained with multiple uses to reduce hypertension, and these plants were easy to get and use. It shows that the boiled leaves were the most frequently used part of the plant. Herbal treatment for hypertension aims to enrich antioxidants, block calcium channels, strengthen the endothelium, inhibit ACE, increase without production, and release and decrease biogenic amines. Herbal plants like lemongrass leaves, ginger, gotu kola leaves, and cat's whiskers are useful for lowering blood pressure levels in routine and intensive use without any side effect intervention by boiling.
Conclusion: Education regarding herbal plants for hypertension is also beneficial because the increased insight and knowledge they have reduced the possibility of hypertension occurring in the community
Keywords
Full Text:
PDFReferences
Verma T, Sinha M, Bansal N, Yadav SR, Shah K, Chauhan NS. Plants Used as Antihypertensive. Nat Products Bioprospect. 2021;11(2):155-184. doi:10.1007/s13659-020-00281-x
Ouedraogo WRC, Belemnaba L, Nitiéma M, et al. Phytochemical study, antioxidant and vasodilatation activities of leafy stem extracts of Flemingia faginea Guill. & Perr. (Barker), a medicinal plant used for the traditional treatment of arterial hypertension. Pharmacol Res - Mod Chinese Med. 2023;7(100231). doi:10.1016/j.prmcm.2023.100231
Health Ministry of Indonesia. Hipertensi Penyakit Paling Banyak Diidap Masyarakat. Published 2019. Accessed August 11, 2023. https://sehatnegeriku.kemkes.go.id/baca/umum/20190517/5130282/hipertensi-penyakit-paling-banyak-diidap-masyarakat/
Kementerian Kesehatan RI Badan Penelitian dan Pengembangan. Hasil Utama Riset Kesehatan Dasar. Kementrian Kesehat Republik Indones. Published online 2018:1-100. https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/1/Laporan%20Riskesdas%202018%20Nasional.pdf
Kementerian Kesehatan Republik Indonesia. Sepuluh Obat Anti Hipertensi. Published 2022. Accessed August 11, 2023. https://yankes.kemkes.go.id/view_artikel/1994/sepuluh-obat-anti-hipertensi
Singh MP, Gohil KJ. Therapeuticefficacy andcost effectiveness ofherbal drugs–A reasonable approach. Pharmacol Res - Nat Prod. 2024;2(December 2023):100009. doi:10.1016/j.prenap.2023.100009
Kamyab R, Namdar H, Torbati M, Ghojazadeh M, Araj-Khodaei M, Fazljou SMB. Medicinal plants in the treatment of hypertension: A review. Adv Pharm Bull. 2021;11(4):601-617. doi:10.34172/APB.2021.090
Laristra T, Farida Y. Penggunaan Obat Herbal pada Pasien Hipertensi di Puskesmas Sibela Surakarta. Pros APC (Annual Pharm Conf. 2019;(March 2019):79-91. https://jurnal.uns.ac.id/Apc/Article/View/35613/23145
Laouali N, Shah S, Macdonald CJ, et al. BMI in the Associations of Plant-Based Diets with Type 2 Diabetes and Hypertension Risks in Women: The E3N Prospective Cohort Study. J Nutr. 2021;151(9):2731-2740. doi:10.1093/jn/nxab158
Faoziyah AR, Rahmah NN, Febriani L, et al. Pemanfaatan Tanaman Obat Sebagai Obat Tradisional sebagai Al ternatif Pengobatan Herbal Pasien Hipertensi dan Diabetes Mellitus. J Pengabdi Masy Al-Irsyad. 2019;I(2):63-71. Available online from: https://jpma.stikesalirsyadclp.ac.id/index.php/alirsyad/about/editorialTeam
Ajeigbe OF, Oboh G, Ademosun AO. Ficus plants in the Co-management of Hypertension and Erectile dysfunction. Phytomedicine Plus. 2021;1(100096):100096. doi:10.1016/j.phyplu.2021.100096
Aumeeruddy MZ, Mahomoodally MF. Traditional herbal therapies for hypertension: A systematic review of global ethnobotanical field studies. South African J Bot. 2020;135:451-464. doi:10.1016/j.sajb.2020.09.008
Nurhidayati LG, Rejeki DS, Pramiastuti O, Murti FK. SOSIALISASI RAMUAN TANAMAN HERBAL UNTUK PENGOBATAN HIPERTENSI PADA MASYARAKAT DESA BLUBUK KECAMATAN DUKUHWARU KABUPATEN TEGAL. J-Abdi J Pengabdi Kpd Masy. 2023;2(10):6689-6694. doi:https://doi.org/10.53625/jabdi.v2i10.5194
Mphuthi DD, Husaini DC. Traditional medicinal plants used by hypertensive patients in Belize: a qualitative evaluation of beliefs and practices. Bull Natl Res Cent. 2022;46(107). doi:10.1186/s42269-022-00789-x
Septianingrum NMAN, Nurpalupi NR, Astuti ND, Hanafi MT, Setiawan SA. Pemanfaatan Terapi Herbal dan Pijat Akupresur Sebagai Pilihan Terapi Hipertensi pada Kelompok Lanjut Usia. Community Empower. 2020;5(3):129-137. doi:10.31603/ce.4351
Al-anbaki M, Cavin A laure, Nogueira RC, et al. Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention. Plants. 2021;10(1018):1-12. doi:https://doi.org/10.3390/plants10051018
Magalhães PKA, Araujo EN, Santos AM, et al. Ethnobotanical and ethnopharmacological study of medicinal plants used by a traditional community in Brazil’s northeastern. Brazilian J Biol. 2022;82:1-12. doi:10.1590/1519-6984.237642
Handayani S, Malik A, Mufidah NI, et al. Ethnopharmacy Study of Herbal Medicine as Antihypertension in Simbang District. J Fitofarmaka Indones. 2022;9(3):7-12. doi:10.33096/jffi.v9i3.914
Xue Z, Li Y, Zhou M, et al. Traditional Herbal Medicine Discovery for the Treatment and Prevention of Pulmonary Arterial Hypertension. Front Pharmacol. 2021;12(November):1-27. doi:10.3389/fphar.2021.720873
Setiawati A, Immanuel H, Utami MT. The inhibition of Typhonium flagelliforme Lodd. Blume leaf extract on COX-2 expression of WiDr colon cancer cells. Asian Pac J Trop Biomed. 2016;6(3):251-255. doi:https://doi.org/10.1016/j.apjtb.2015.12.012
Goit LN, Yang S. Treatment of Hypertension: A Review. Yangtze Med. 2019;03(02):101-123. doi:10.4236/ym.2019.32011
Aatif M, Raza MA, El Oirdi M, et al. Bioassay-Guided Alkaloids Isolation from Camellia sinensis and Colchicum luteum: In Silico and In Vitro Evaluations for Protease Inhibition. Molecules. 2023;28(6). doi:10.3390/molecules28062459
Bhattacharjee S, Elancheran R, Dutta K, Deb PK, Devi R. Cardioprotective potential of the antioxidant-rich bioactive fraction of Garcinia pedunculata Roxb. ex Buch.-Ham. against isoproterenol-induced myocardial infarction in Wistar rats. Front Pharmacol. 2022;13(October):1-21. doi:10.3389/fphar.2022.1009023
Eff ARY, Rahayu ST, Mahayasih PG, Januarko MU. Standardization of Indonesian traditional antihypertensive medicines (JAMU) through the ACE inhibitor mechanism. Pharmacogn J. 2020;12(3):422-429. doi:10.5530/pj.2020.12.65
Zuhrotun A, Hasanah AN, Sulistiyaningsih R. Edukasi Pemanfaatan Tumbuhan Berkhasiat Obat menjadi Sediaan Herbal. Media Karya Kesehat. 2020;3(2). doi:10.24198/mkk.v3i2.24887
Nursiswati, Harun H, Andhika D. Social Media Campaign tentang Aktivitas Produksi dan Konsumsi Healthy Veggie Juice dalam Pencegahan Penyakit Kronis. Media Karya Kesehat. 2023;6(1):20-29. doi:10.24198/mkk.v6i1.42765
DOI: https://doi.org/10.22146/jmpf.89076
Article Metrics
Abstract views : 163 | views : 123Refbacks
- There are currently no refbacks.
Copyright (c) 2024 JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.