Suplementasi vitamin A dan asupan zat gizi dengan serum retinol dan morbiditas anak 1-3 tahun

https://doi.org/10.22146/ijcn.17938

Milliyantri Elvandari(1*), Dodik Briawan(2), Ikeu Tanziha(3)

(1) Magister Gizi Masyarakat, Fakultas Ekologi Manusia Institut Pertanian Bogor
(2) Departemen Gizi Masyarakat, Fakultas Ekologi Manusia Institut Pertanian Bogor
(3) Departemen Gizi Masyarakat, Fakultas Ekologi Manusia Institut Pertanian Bogor
(*) Corresponding Author

Abstract


Background: Morbidity of infectious diseases in developing countries is a public health concern because the prevalence is still high, particularly for children under five years. Vitamin A  intake was one of factors that may affect morbidity.

Objective: The objective of this study was to analyze  relation between vitamin A supplementation, nutrition intake with vitamin A status and relation between vitamin A supllementation, nutrition intake, vitamin A status with morbidity.

Method: The study was an cross-sectional study. This research was conductedin February-March 2016 in Kudus and Grobogan Central Java. Subjectsin this study were children aged 1-3 years(n=140). Retinol serum was collected by taking blood sample through the vein then was analyzed using HPLC, nutrients intake with food recall 2x24jam, and structured interviews with mother children. Data were analyzed with Chi-Square test.

Results: The study found that 68 subjects (48.6%) were not took vitamin A supplemantation capsule. Prevalence of childrens had nutrient deficiency (<90% RDA) were relatively high 68.6% energy; 47.1% protein; 70.7% fat; and the prevalence of vitamin A defeciency (<77% RDA)  were relatively high 60%. A number of 24.2% subjects had low retinol serum (<20μg/dl). Supplementation vitamin A, fat and vitamin A intake correlated with retinol serum (p<0.05). Supplementation vitamin A, intake of vitamin A, vitamin C, zinc and retinol serum correlated with morbidity (p<0.05).

Conclusion: Childrens who were not took vitamin A supplemantation capsule, deficiency intake of vitamin A, vitamin C, zinc and low retinol serum had higher morbidity.


Keywords


morbidity; retinol serum; vitamin A supplementation

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References

  1. Kementerian Kesehatan Republik Indonesia. Undang-undang Kesehatan No.36 Tahun 2009
  2. Haryono R. Keperawatan medikal bedah sistem pencernaan. Yogyakarta: Gosyen Publishing; 2012.
  3. Widoyono. Penyakit tropis epidemiologis, penularan, pencegahan, dan pemberantasannya. Jakarta: Erlangga Medical Series; 2008.
  4. World Health Organization (WHO). Pakistan: IDP hosting and crisis affected districts, Khyber, Pakhtunkhwa, week 21, 22-28 May 2010. WHO: Weekly Morbidity and Mortality Report; 2010.
  5. Kementerian Kesehatan Republik Indonesia. Buletin jendela data dan informasi kesehatan volume 2 triwulan 2. Jakarta: Kementerian Kesehatan RI; 2013.
  6. Kementerian Kesehatan Republik Indonesia. Laporan riset kesehatan dasar nasional tahun 2013. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kemenkes RI; 2013.
  7. Dinas Kesehatan Republik Indonesia. Buku profil kesehatan Provinsi Jawa Tengah tahun 2012. Semarang; Dinas Kesehatan RI; 2013.
  8. Haidar J, Tsegaye D, Mariam DH, Tibeb HN, Muroki NM. Vitamin A supplementation on child morbidity. East African Med J 2003;80(1):17-21.
  9. Anugraheni HS, Kartasurya MI. Faktor risiko kejadian stunting pada anak usia 12-36 bulan di Kecamatan Pati, Kabupaten Pati [Tesis]. Semarang: Universitas Diponegor; 2012.
  10. Almatsier S. Prinsip dasar ilmu gizi. Jakarta: Gramedia Pustaka Utama; 2004.
  11. Gibson RS. Principles of Nutritional Assesment. New York: Oxford University Press; 2005.
  12. Sommer A, West KP. Vitamin A deficiency : health, survival, and vision. New York: Oxford University Pr; 1996.
  13. Karyadi E, West CE, Schltink W, Nelwan R, Gross R, Meer J, et al. A doubleblind, placebo-cotrolled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effect on clinical response and nutritional status. Am J Clin Nutr 2002;75(4):720-7.
  14. Steel RGD, Torrie JH. Prinsip dan prosedur statistika suatu pendekatan biometrik. Jakarta: PT. Gramedia; 1991.
  15. Sandjaja, Sudikno, Jus’at I. Konsumsi minyak goreng dan vitamin A pada beberapa kelompok umur di dua kabupaten. Penelitian Gizi dan Makanan 2015;38(1):1-10.
  16. Food and Agriculture Organization (FAO). Interim summary of conclusions and dietary recommendations on total fat & fatty acids. Geneva: FAO/WHO Expert Consultation on Fats and Fatty Acids in Human Nutrition; 2008.
  17. Departemen Kesehatan. Deteksi dan tatalaksana kasus xeroftalmia, pedoman bagi tenaga kesehatan. Jakarta: Direktorat Jendral Pembinaan Kesehatan Masyarakat; 2003.
  18. Kementerian Kesehatan Republik Indonesia. Angka kecukupan gizi (AKG) 2013. Jakarta: Kementerian Kesehatan RI; 2013.
  19. Departemen Kesehatan. Buku pedoman akselerasi cakupan kapsul vitamin A. Jakarta: Departemen Kesehatan; 2000.
  20. Paiva A, Rondó PHC , Reinaldo LGC, Pedraza DF, Ruz M. The effect of vitamin A supplementation on retinol concentrations of children with anaemia. Nutria Hospitalaria 2012;27(6):2151-2.
  21. Ferraz IS, Daneluzzi, Vannucchi H, Jordao Jr.AA, Ricco RG, Flores H, et al. Detection of vitamin A deficiency in Brazilian preschool children using the serum 30-day dose-response test. Eur J Clin Nutr 2004;58(10):1372-7.
  22. Rosales FJ. Vitamin A supplementation of vitamin a deficient measles patients lowers the risk of measles-related pneumonia in Zambian children. J Nutr 2002;132(12):3700-3.
  23. Imdad A, Yacob MY, Sudfeld C, Haider BA, Black RE, Bhutta ZA. Impact of vitamin A supplementation on infant and childood mortality. BMC Public Health 2011;11(Suppl 3):S20.
  24. Saifuddin. Hubungan suplementasi vitamin A dengan status kesehatan balita di Kecamatan Jeumpa Kabupaten Bireun [Tesis]. Medan: Universitas Sumatera Utara Medan; 2009.
  25. Ridwan E. Kapsul vitamin A dan morbiditas anak balita: analisis data Riskesdas 2007. Gizi Indonesia 2012;35(1):64-72.
  26. Jalal F, Nesheim MC, Agus Z, Sanjur D, Habicht JP. Serum retinol concentrations in children are affected by food sources of β-carotene, fat intake, and antehelminthic drug treatment. Am J Clin Nutr 1998;68:623-9.
  27. Almatsier S. Prinsip dasar pangan dan gizi. Jakarta: Gramedia Pustaka Utama; 2011.
  28. Widoyono. Penyakit tropis epidemiologi penularan dan pemberantasannya. Jakarta (ID): Erlanggga; 2005.
  29. Maitatorum E, Zulaekah S. Status gizi, asupan protein, asupan seng dan kejadian ISPA anak balita di perkampungan kumuh Kota Surakarta. Jurnal Kesehatan 2011;4(1):21-30.
  30. Cresci G, Martindale R. Nutrition in critical illness. Dalam: Berdanier C, Dwyer J, Feldman E, penyunting. Handbook of nutrition and food. Edisi ke 2. London: CRC Press; 2008.
  31. Heys S, Schofield A, Wahle W. Immunonutrition in clinical practice: what is the current evidence. Nutr Hosp 2004;14(6):325-32.
  32. Almatsier S, Soetardjo S, Soekatri M. Gizi seimbang dalam daur kehidupan. Jakarta: Gramedia Pustaka Utama; 2011.
  33. Fawzi WW, Herrera MG, Willett WC, Nestel P, el Amin A, Mohamed KA. Dietary vitamin A intake and the incidence of diarrhea and respiratory infection amnong Sudanese children. J Nutr 1995;125(5):1211-21.
  34. Wintergerst ES, Maggini S, Hornig DH. Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab 2007;51(4):301-23.
  35. Winarsi H. Antioxidan alami dan radikal bebas. Jogyakarta: Kanisius; 2007.
  36. Fitriyah R and Mahmudiono T. Hubungan asupan dan pola konsumsi vitamin A, protein dan zinc dengan kejadian ISPA dan status gizi pad anak. Media Gizi Indonesia 2013;9:60-5.
  37. Fedriyansyah, Nazir HZ, Theodorus, Husin S. Hubungan kadar seng dan vitamin A dengan kejadian ISPA dan diare pada anak. Sari Pediatri 2010;12(4):241-6.
  38. Hotz C, Chileshe J, Siamusantu W, Palaniappan U, Kafwembe E. Vitamin A and infection are associated with plasma retinol among pre-school children in rural Zambia. Public Health Nutr 2012;15(9):1688-96.



DOI: https://doi.org/10.22146/ijcn.17938

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