Perbedaan kadar seng serum dan kadar c-reactive protein pada anak balita dengan kadar serum retinol normal dan tidak normal
Kadek Tresna Adhi(1*), Bambang Wirjatmadi(2), Meriyana Adriani(3)
(1) PS, IKM Universitas Udayana Bali
(2) FKM, Universitas Airlangga Surabaya
(3) FKM, Universitas Airlangga Surabaya
(*) Corresponding Author
Abstract
Background: Vitamin A Defciency (VAD) is one of the major nutritional problem, and many occur in developing countries. VAD occurs when serum retinol concentration <20 tg / dl (0.07 μmol / L). Serum retinol levels will decrease during the acute phase response (elevated CRP) and also caused by zinc defciency. This interaction causes inhibition of linear growth.
Objective: The objective of this research is to study the differences in levels of serum zinc and CRP levels in infants and children with normal serum retinol (≥ 20 tg / dl) and abnormal (≥ 20 tg / dl) in the Village of Mojo, District Gubeng, Surabaya.
Method: Results of the analysis was divided into two categories: 1) normal serum retinol (≥ 20 tg / dl), and 2) abnormal levels of serum retinol (<20 tg / dl). For serum zinc levels, laboratory examination was performed by AAS method (Atomic Absorption Spectrophotometry). CRP level was done by agglutination test method (CRP latex) with results in the form of semi-quantitative analysis. The collection of data includes the frequency characteristic of children and the sick for a month with interviews conducted using a questionnaire. Consumption data using dietetic (2x24-hour recall). Analysis of data using two independent samples t test.
Results: The results showed that there was no difference in characteristics, levels of consumption and CRP levels of children under fve (p> 0.05). While there are differences in the frequency of pain and zinc (p <0.05).
Conclusion: No difference in zinc levels in both groups, whereas CRP levels did not show different results. It was recommended that further research on the interaction of research results with linear growth as well as environmental factors and personal hygiene to prevent infection that can affect serum retinol.
Keywords
Full Text:
PDFReferences
Hellen Keller International. Indonesia dalam masa transisi. Buletin Kesehatan dan Gizi Th. 6. Ed.1 Juni [serial online] 2004 [cited 2007 Des 14]. Avalaible from: http://www.hki-indo.org/vitamina.
Widya Karya Pangan dan Gizi. Prosiding Ketahanan Pangan dan Gizi di Era Otonomi aerah dan Globalisasi WKNPG VIII LIPI Jakarta; 2004. 183-96.
Depkes RI. Pedoman pemberian kapsul vitamin A dosis tinggi. Jakarta: Departemen Kesehatan RI; 2005.
Sommer, A. Defisiensi vitamin A dan akibatnya: panduan lapangan untuk deteksi dan pengawasan. Alih bahasa: Vivi Sadikin. Ed.3. EGC: Jakarta; 2004.
Gibson RS. Principles of nutitional assesment 2nd ed. New York: Oxford University Press; 2005.
Atmarita. Analisis situasi gizi dan kesehatan masyarakat. Prosiding Ketahanan Pangan dan Gizi di Era Otonomi Daerah dan Globalisasi WKNPG VIII Jkarta; 2004. 129-61.
Merchant. Water and sanitation associated with improved child growth. Eur J of Clin Nutr 2003; 57: 1562-68.
Mundiastuti, Wirjatmadi. Efek pemberian suplemen zinc terhadap status gizi anak SD di SDN Bendul Merisi dan di SD Islam An Najiyyah, Kelurahan Sidosermo, Kecamatan Wonocolo, Kota Surabaya. Surabaya: MGI 2005; (4): 301-3.
Arisman. Gizi dalam daur kehidupan: Buku Ajar Ilmu Gizi. Jakarta: EGC; 2004.
Stephensen CB. Burden of infection on growth failure. Symposium: “Cause and Etiology of Stunting”, April 1998. The Journal of Nutrition. Academic Research Library 1999. 534S-7S.
Lemeshow S, Hosmer D, Klar J, Lwanga SK. Adequacy of sample size in health studies. (terjemahan) Pramono D. Yogyakarta: Gadjah Mada University Press; 1997.
WHO. Manual of basic technique for a health laboratory. Ed 2 . 2003. 333-8.
Semba RD. Vitamin A dalam diet and human immune function. New Jersey: Human Press Inc 2004. 105- 20.
Cser MA. Majchrzak D, Rust P, Sziklai I, Kovocs I, Bocskai E, Elmadfa I. Serum carotenoid and retinol levels during childhood infections. Ann Nutr Metab 2004; 48: 156-162.
Hidayat A. Seng (Zinc) esensial bagi kesehatan. Jakarta: Majalah Ilmiah Fakultas Kedokteran Trisakti 1999; 18 (1) 2: 20.
Thane CW, Bates CJ, Prentice A. Zinc and vitamin A intake and status in a national sample of british young people aged 4-18 y. Eur J of Clin Nutr 2004; 58: 363- 75.
Ruz M, Codoceo J, Galgani J, Munoz L, dan Bosco C. Single and multiple selenium-zinc-iodine deficiency affect rat thyroid metabolism and ultrastructure. J. Nutr 1999; 29: 174. 177. 179.
Baum MK, Campa A. HIV infection dalam diet and human immune function. New Jersey: 2004. 308-9.
Thurham, Clewes N. Effects of infection on nutritional and immune status dalam diet and human immune function. New Jersey: Human Press Inc 2004. 35-47.
McLaren DS, Frigg M, Sight and life manual on vitamin a deficiency disorders (VADD). Ed 2. Task Force Sight and Life: Basel Switzerland; 2001. 21-144.
Kongsbak K, Wahed MA, Friis H, Thilsted SH. Acute phase protein levels, t.trichiura, and maternal education are predictors of serum zinc in a cross-sectional study in Bangladeshi Children. The Journal of Nutrition; 136 (8). Academic Research Library 2006. 2262.
Mulyati S, Julia M, Mursyid A. Pengaruh suplementasi besi-folat, vitamin A dan seng terhadap durasi dan frekuensi sakit ISPA pada anak sekolah dasar dengan status gizi kurang di Kabupaten Bantul. Jurnal Gizi Klinik Indonesia 2007; 4 (1): 11-8.
Gambir J, Julia M, Juffrie M. Pengaruh suplementasi zink (Zn) terhadap diare pada penderita umur 6-36 bulan yang dirawat di RSUD Dr. Soedarso Pontianak, Kalimantan Barat. Jurnal Gizi Klinik Indonesia 2005; 1 (3): 113-8.
Sandstead H. Zinc defciency , a public health problem. Department of preventive medicine and community health. University of Texas Medicine Branch Galveston 1991; 60-4. 25.
Gibson RS, Manger MS, Krittaphol W, Pongcharoen T, Gowachirapant S, Bailey KB, Winichagoon P. Does zinc defciency play a role in stunting among Primary School Childrenin NE Thailand?.British Journal of Nutrition (97) 2007: 167-75.
DOI: https://doi.org/10.22146/ijcn.17737
Article Metrics
Abstract views : 2488 | views : 2231Refbacks
- There are currently no refbacks.
Copyright (c) 2017 Jurnal Gizi Klinik Indonesia (The Indonesian Journal of Clinical Nutrition)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.