Asupan vitamin B3 (niasin), C, E, dan serat berhubungan dengan dislipidemia pada penyakit jantung koroner di RS DR. Mohammad Hoesin Palembang

Muzakar Muzakar; Kris Dinarti; Herni Astuti

doi:10.22146/ijcn.17719

Asupan vitamin B3 (niasin), C, E, dan serat berhubungan dengan dislipidemia pada penyakit jantung koroner di RS DR. Mohammad Hoesin Palembang

https://doi.org/10.22146/ijcn.17719

Muzakar Muzakar^(1*), Kris Dinarti⁽²⁾, Herni Astuti⁽³⁾

(1) Poltekkes Palembang, Sumatera Selatan
(2) Bagian Kardiologi dan Vaskular, Fakultas Kedokteran Universitas Gadjah Mada
(3) Instalasi Gizi RSUP Dr. Sardjito
(*) Corresponding Author

Abstract

Background: Coronary heart disease is a health problem both in developed and developing countries including Indonesia. The result of household health survey in 1992 and 1995 indicated that coronary heart disease was the first cause of death with the prevalence as much as 16.5% and 19% subsequently. Coronary heart disease is caused by many factors such as hypertension, hyperlipidemia, obesity, smoking and diabetes mellitus. High intake of unsaturated fat for a long time can increase blood lipid level. Efforts to lowering blood cholesterol can be made by managing macro nutrient intake as well as micro nutrient intake such as vitamin B₃, C, E, and fibers.

Objective: To find out the relationship between intake of vitamin B₃ (niacin), C, E and fibers and dyslipidemia in coronary heart disease at dr. Mohammad Hoesin Hospital of Palembang.

Method: The study was analytic observational which used cross sectional design. Subject of the study were dyslipidemia patients of coronary heart disease who were newly diagnosed. There were as many as 50 patients who fulfilled inclusion and exclusion criteria and were purposively chosen. The study was carried out at cardiology room from October 2007 to February 2008. Data of intake were obtained from questionnaires of quantitative food frequency and processed using computer. Chi square test was used to identify the relationship between intake and lipid profile; Spearman rho correlation was used to find out the level of relationship; and odds ratio was used to identify the risk.

Result: There was significant relationship between intake of vitamin B₃, C, E and fibers and total cholesterol (p < α). There was significant relationship between intake of vitamin E and triglyceride (p = 0.015). There was significant relationship between intake of vitamin B₃, E and fibers and high density lipoprotein cholesterol (p < α). There was significant relationship between intake of vitamin B₃, C, E and fibers and low density lipoprotein cholesterol (p < α).

Conclusion: There was relationship between low intake of vitamin B₃, C, E and fibers of dyslipidemia patients in coronary heart disease.

Keywords

coronary heart disease; vitamin B3; vitamin C; vitamin E; fibers

Full Text:

PDF

References

Sugiani PPS, Hadi H, Pramantara IDP. Asupan Gizi sebagai Faktor Risiko Penyakit Infark Miokard Akut di RS Sanglah Denpasar. Jurnal Gizi Klinik Indonesia 2004; I(2): 67-75 .

Rukmasari EA, Hadi H, Achdiono DNW. Pengaruh Suplemetasi Vitamin C dan Vitamin E terhadap Profil Lipid pada Pasien Penyakit Jantung Koroner di Poliklinik Kardiologi RSU dr. Slamet Garut. Sains Kesehatan 2006; 19(2): 185-95.

Waspadji S, Suyono S, Sukardji K, Hartati BSA. Pengkajian Status Gizi Epidemiologi. Jakarta: FKUI; 2003.

Khomsan A. Pangan dan Gizi untuk Kesehatan. Jakarta: Rajagrafndo Persada; 2003.

Lemeshow S, David WH. Janelle K. Sample Size Determination in Health Studies A Practical Manual. Geneva: WHO; 1997

Rab T. Penyakit Jantung Koroner Bukan Merupakan Masalah Asalkan… . Jakarta: Arcan; 1995.

Sulastri D. Rahayuningsih S, Purwantyastuti. Pola Asupan Lemak, Serat dan Antioksidan serta Hubungannya dengan Profil Lipid pada Laki-laki Etnik Minangkabau. Majalah Kedokteran Indonesia 2005; 55(2): 61-6.

Soeharto I. Serangan jantung dan Stroke Hubungannya dengan Lemak dan Kolesterol. Jakarta: Gramedia Pustaka Utama; 2004.

Gibson SR. Nutritional Assessment: A Laboratory Manual. New York: Oxford University Press; 1993.

Gibson SR. Principle of Nutritiion Assessment. New York, Oxford University Press; 2005.

Emmert DH, Kirchner JT. The Role of Vitamin E in the Prevention of Heart Disease. American Medical Association [serial online] 1999 [cited 2007 June 19]. Available from: www.englandmedicaljournal.com.

Djunaedi H. Manfaat Serat Untuk Kesehatan. Jakarta: Jurnal Ilmiah Kesehatan RSPAD Gatot Soebroto 2001; 2(1).

Almatsier S. Prinsip Dasar Ilmu Gizi. Jakarta: Gramedia Pustaka Utama; 2003.

Linder MC. Biokimia Nutrisi dan Metabolisme. UI Press; 2006

Schumm DE. Intisari Biokimia. Sadikin. Jakarta, Binarupa Aksara; 1993.

Mayes PA. Pengangkutan dan Penyimpanan Lipid dalam Biokimia Harper. Alih Bahasa: Andry Hartono. Jakarta: EGC; 2003.

Supardan. Metabolisme Lemak. Malang: FK Unibraw; 1999

Silalahi J. Makanan Fungsional. Yogyakarta: Kanisius; 2006

Wendra Ali. Penyakit Jantung Hipertensi dan Nutrisi. Jakarta: Bumi Aksara; 1993.

Nurbekti W, Yuliani S, Widyaningsih W. Pengaruh Perasan Segar Jeruk Nipis (Citrus aurantifolia Swingle) Terhadap Kadar Kolesterol Serum Tikus Putih Jantan Galur Wistar yang diberi Diet Lemak Tinggi. Jurnal tar yang diberi Diet Lemak Tinggi. Jurnal Jurnal Ilmu Farmasi 2006; 5(1): 43-5.

DOI: https://doi.org/10.22146/ijcn.17719