EFFECT OF NARROW BAND ULTRA VIOLET B (NBUVB) PHOTOTHERAPY TO DECREASE SERUM FERRITIN LEVELS IN URAEMIC PRURITUS PATIENTS WHOSE UNDERGOING REGULAR HEMODIALYSIS IN DR. SARDJITO HOSPITAL YOGYAKARTA

Muhammad Himawan Nugroho; Muhammad Robikhul Ikhsan; Iri Kuswadi

doi:10.22146/actainterna.35842

EFFECT OF NARROW BAND ULTRA VIOLET B (NBUVB) PHOTOTHERAPY TO DECREASE SERUM FERRITIN LEVELS IN URAEMIC PRURITUS PATIENTS WHOSE UNDERGOING REGULAR HEMODIALYSIS IN DR. SARDJITO HOSPITAL YOGYAKARTA

https://doi.org/10.22146/actainterna.35842

Muhammad Himawan Nugroho^(1*), Muhammad Robikhul Ikhsan⁽²⁾, Iri Kuswadi⁽³⁾

(1) Specialty of training program, Department of Internal Medicine, Faculty of Medicine, Universitas Gadjah Mada
(2) Endocrine Metabolic and Diabetes Division, Department of Internal Medicine, Faculty of Medicine, Universitas Gadjah Mada
(3) Nephrology and Hypertension Division, Department of Internal Medicine, Faculty of Medicine, Universitas Gadjah Mada
(*) Corresponding Author

Abstract

ABSTRACT
Background. Uraemic pruritus is the complaint most often found in patients with terminal renal failure (15-49 %) and hemodialysis patients (50-90%). Mikroinflamasi role as ferritin be one cause. Phototherapy NBUVB theoretically can lower serum ferritin, thereby reducing the intensity of pruritus in patients .
Objective. The main objective to determine the effect of phototherapy NBUVB to decrease serum ferritin levels of uremic pruritus patients undergoing regular hemodialysis. The next goal NBUVB know the influence of phototherapy to decrease the intensity of itch (VAS).
Methods. Quasi experimental with pre-post comparison design, comparing the reduction in serum ferritin levels before and after phototherapy NBUVB, here p < 0.05 is said to be significant.
Results. A total of 29 subjects who underwent the study protocol, 18 were male, the average age was 55.7 years, the largest cause of kidney disease is hypertension (48.3%), average 4.2 years old undergoing hemodialysis. There was a decrease which signifkan where median serum ferritin levels before phototherapy 1693 ng/mL (12.05 to 6000) and after phototherapy 275 ng/mL (12.55-6000) with p 0.001. The degree of intensity of pruritus also decreased significantly where the median VAS before phototherapy 7 (4-10) and after phototherapy 4 (2-8) with p 0.001.
Conclusions. Phototherapy NBUVB lowering serum ferritin levels and degrees of intensity of pruritus (VAS) of uraemic pruritus in patients undergoing regular hemodialysis.
Keywords : CRF (Chronic Renal Failure), Hemodialysis, Uraemia pruritus, Serum Ferritin, Phototherapy NBUVB

Keywords

CRF (Chronic Renal Failure), Hemodialysis, Uraemia pruritus; Serum Ferritin; Phototherapy NBUVB

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DOI: https://doi.org/10.22146/actainterna.35842