IRON CHELATING AND ANTIRADICAL ACTIVITY OF KAYU MANIK LEAVES ( Trema orientalis )

Salprima Yudha S.; Eka Angasa; Sri Ningsih; Syalfinaf Manaf; Suli Anggria Murni; Fatan Umbara

doi:10.22146/ijc.21410

IRON CHELATING AND ANTIRADICAL ACTIVITY OF KAYU MANIK LEAVES (Trema orientalis)

https://doi.org/10.22146/ijc.21410

Salprima Yudha S.^(1*), Eka Angasa⁽²⁾, Sri Ningsih⁽³⁾, Syalfinaf Manaf⁽⁴⁾, Suli Anggria Murni⁽⁵⁾, Fatan Umbara⁽⁶⁾

(1) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(2) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(3) Agency for the Assessment and Application of Technology, Gedung BPPT, Jl. MH. Thamrin 8, Jakarta 10340
(4) Department of Biology, University of Bengkulu, Jl. Raya Kandang Limun Bengkulu 38371A
(5) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(6) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(*) Corresponding Author

Abstract

A methanol soluble fraction extracted from Kayu Manik leaves (Trema orientalis) from Seluma, Bengkulu, exhibited an antiradical activity 69.73% (scavenging activity of the stable 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical) that was almost similar to that of 1 mM ascorbic acid. On the other hand, the iron chelating activity was 40.74%. We believe that it would be useful to take the results as an alternative for processing industries and can be observed as a good source of new agent for iron chelator.

Keywords

Antiradical; Flavonoid; Iron chelating; Kayu Manik Leaves; Thalasemia

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DOI: https://doi.org/10.22146/ijc.21410