Kadar timbal dalam darah pada petugas stasiun pengisian bahan bakar

https://doi.org/10.22146/bkm.12927

Brian Klopfleisch(1*), Adi Heru Sutomo(2), Susi Iravati(3)

(1) Departemen Perilaku Kesehatan, Lingkungan, dan Kedokteran Sosial Fakultas Kedokteran Universitas Gadjah Mada
(2) Departemen Kedokteran Keluarga, Komunitas dan Bioetika Fakultas Kedokteran, Universitas Gadjah Mada
(3) Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Blood lead level among workers in gas station

Purpose

This study aimed to determine the effect of lead levels with oxidative stress in gas station officers in the Sleman region through measurement of malondialdehyde levels (MDA).

Methods

This research was an observational analytic study involving 43 gas station workers. Blood lead levels were measured by atomic absorption spectrophotometer (SSA) methods. Serum MDA levels were measured by the TBRs methods.

Results

This study found the average lead concentration in blood of SPBU officers was 62.174 μg/L while the serum MDA level obtained mean 5.86 μmol/L. The result of statistical tests using Pearson correlation showed that there was a significant influence between blood lead level and MDA level (p = 0.000) with very strong correlation strength (r = 0.8432).

Conclusion

Gas station officers are susceptible to exposure to lead, so it is necessary to prevent the deterioration of health conditions by the use of personal protective equipment (PPE), healthy lifestyle, and routine medical check-ups


Keywords


blood lead levels; malondialdehid; gas station workers



References

  1. Al-Fartosy AJ, Awad NA, Shanan SK. Biochemical correlation between some heavy metals, malondialdehyde and total antioxidant capacity in blood of gasoline station workers. International Research Journal of Environmental Sciences. 2014;3(9):56-60.
  2. Lubis B, Rosdiana N, Nafianti S, Rasyianti O, Panjaitan FM. Hubungan keracunan timbal dengan anemia defisiensi besi pada anak. CDK-200. 2013;40(1):17-21
  3. Kim J, Lee Y, Yang M. Environmental exposure to lead (Pb) and variations in its susceptibility. Journal of Environmental Science and Health, Part C. 2014 Apr 3;32(2):159-85
  4. Ati PW, Murbawani EA. Hubungan kecukupan asupan zat besi dan kadar timbal darah dengan kadar hemoglobin anak jalanan usia kurang dari 8 tahun di kawasan Pasar Johar Semarang (Doctoral dissertation, Diponegoro University).
  5. Gusnita D. Pencemaran logam berat timbal (Pb) di udara dan upaya penghapusan bensin bertimbal. Berita Dirgantara. 2012;13(3).
  6. Kawatu P. Analisis Kadar Timbal Darah dan Penyakit Hipertensi pada Petugas Stasiun Pengisian Bahan Bakar Umum di Kota Manado. Chemistry Progress. 2009;2(2).
  7. Muliyadi M. Paparan timbal udara terhadap timbal darah, hemoglobin, cystatin c serum pekerja pengecatan mobil. Jurnal Kesehatan Masyarakat. 2015 Sep 11;11(1):87-95.
  8. Tayrab E, Abdelrahman N, Tirba AK. Blood lead level among fuel station workers at Khartoum city. American Journal of Research Communication. 2014;2(6).
  9. Laila NN, Shofwati I. Kadar timbal darah dan keluhan kesehatan pada operator wanita SPBU. Jurnal Kesehatan Reproduksi. 2013;4(1 Apr):41-9
  10. Rosyidah H, Djannah SN. Hubungan antara kadar pb dalam darah dengan kejadian hipertensi pada operator SPBU di kota Yogyakarta. Jurnal Kesehatan Masyarakat (Journal of Public Health). 2013 Apr 13;4(2).
  11. Ercal N, Gurer-Orhan H, Aykin-Burns N. Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage. Current topics in medicinal chemistry. 2001 Dec 1;1(6):529-39.
  12. Farmand F, Ehdaie A, Roberts CK, Sindhu RK. Lead-induced dysregulation of superoxide dismutases, catalase, glutathione peroxidase, and guanylate cyclase. Environmental Research. 2005 May 1;98(1):33-9.
  13. Miyamoto, S., Alves, A., Noguire, L., Helen ,M., Di Mascio, P. Evaluation of Malondialdehyde Levels. Oxidative Stress in Aquatic Ecosystems. Blackwell Publishing Ltd. United Kingdom. 2012.
  14. Valko M, Rhodes C, Moncol J, Izakovic MM, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-
  15. Ściskalska M, Zalewska M, Grzelak A, Milnerowicz H. The influence of the occupational exposure to heavy metals and tobacco smoke on the selected oxidative stress markers in smelters. Biological trace element research. 2014 Jun 1;159(1-3):59-68.
  16. Flora SJ, Mittal M, Mehta A. Heavy metal induced oxidative stress & its possible reversal by chelation therapy. Indian Journal of Medical Research. 2008 Oct 1;128(4):501.
  17. Awad, N.A., Sanaa, K.S., Adnan, J.M.A. Effect of Lead Exposure on Malondialdehyde (MDA) Level and Some Biochemical Parameter in Workers of Gasoline Stations. Research Journal of Pharmaceutical, Biological and Chemical Sciences.Vol 5(6). 2015.
  18. Mutlu-Türkoğlu Ü, İlhan E, Öztezcan S, Kuru A, Aykaç-Toker G, Uysal M. Age-related increases in plasma malondialdehyde and protein carbonyl levels and lymphocyte DNA damage in elderly subjects. Clinical biochemistry. 2003 Jul 1;36(5):397-400.
  19. Poljšak B, Dahmane R. Free radicals and extrinsic skin aging. Dermatology research and practice. 2012;2012.
  20. Mouhamed DH, Ezzaher A, Neffati F, Douki W, Gaha L, Najjar MF. Study of a marker of oxidative stress in smokers: The malondialdehyde. Immuno-Analyse & Biologie Specialisee. 2012 Aug 1;27(4):153-8.
  21. Kusumawardhani AD. Faktor risiko yang berhubungan dengan kadar hemoglobin dan malondialdehid pada petugas parkir yang terpapar karbon monoksida di swalayan Surakarta. Jurnal Kesehatan Masyarakat (e-Journal). 2015 Mar 2;3(1):305-17.
  22. Kumari Suchetha N.,Damodara Gowda K.M., Sukesh. N., Madhu L.N., Kathyayani.Effect of yoga therapy on body mass index and oxidative status. Nitte University Journal of Health Science. Vol . No. 1- 3. 2011.
  23. Yesilbursa D, Serdar Z, Serdar A, Sarac M, Coskun S, Jale C. Lipid peroxides in obese patients and effects of weight loss with orlistat on lipid peroxides levels. International journal of obesity. 2005 Jan;29(1):142.
  24. Higashi Y, Sasaki S, Nakagawa K, Kimura M, Noma K, Sasaki S, Hara K, Matsuura H, Goto C, Oshima T, Chayama K. Low body mass index is a risk factor forimpaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress. Journal of the American College of Cardiology. 2003 Jul 16;42(2):256-63.
  25. Khajehnasiri F, Mortazavi SB, Allameh A, Akhondzadeh S, Hashemi H. Total antioxidant capacity and malondialdehyde in depressive rotational shift workers. Journal of environmental and public health. 2013;2013.
  26. Al-Attar AM. Antioxidant effect of vitamin E treatment on some heavy metals-induced renal and testicular injuries in male mice. Saudi journal of biological sciences. 2011 Jan 1;18(1):63-72.



DOI: https://doi.org/10.22146/bkm.12927

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