* Corresponding Author
The rotavirus causing acute gastroenteritis in children of under 5-year of age in Indonesia 1972-2018: a review
https://doi.org/10.19106/JMedSci005301202105 Abu Tholib Aman(1*)
(1) Department of Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
infection that had been the major cause of severe diarrhea in children of under
5-years of age in Indonesia, despite numerous publications elaborating rotavirus
infection in some geographic areas of Indonesia. A review was conducted
towards 52 published articles covering rotavirus research in Indonesia during
period of 1972-2018.A thirty three selected articles were match with review
criteria which comprises rotavirus positive rate, clinical features, and severity
of rotavirus infection, as well as genotypes of the rotavirus. Rotavirus has been
known as the major cause of severe diarrhea among children under 5 years of
age world wide including in Indonesia. The rotavirus positive rates were range
from 31.1 to 90.9%, which variably to different subject’s population, study
criteria and methods, and time. Rotavirus can cause severe diarrhea with
majority of infected children suffered from dehydration, vomiting, and fever.
The first genotyping conducted in Indonesia in the early 1980s revealed the
predominant genotypes were G3 and G4, followed by G2, and small proportion
of G1 and mixed genotypes. However the following decades G1 and G2 were on
the raise with G3 predominantly re-appeared on 2015. G9 was first identified in
2004, and occasionally detected until 2015. The P genotyping revealed P[4], P[6],
and P[8] were the common genotypes detected. Mixed and untyped genotypes
were also detected in various proportion. Rotavirus diarrhea is a vaccination
preventable disease, after natural infection, the immune system will produce
protective antibodies that will protect from infection of both homotypic and
heterotypic, however homotypic infection will protect stronger. Therefore this
review recommends continuous rotavirus genotypes surveillance in Indonesia.
Keywords
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Tate, J. E., Burton, A. H., Boschi-Pinto, C., Parashar, U. D. & World Health Organization-Coordinated Global Rotavirus Surveillance, N. Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000-2013. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 62 Suppl 2, S96-S105, doi:10.1093/cid/civ1013 (2016).
Ana, E. F. et al. Identification of rotavirus infection during diarrhoea outbreaks among children under five years of age in Lampung, Indonesia. Paediatr Croat.
, 100-104 (2019).
Utsumi, T. et al. G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 2018. J Infect Public Health, doi:10.1016/j.jiph.2020.05.002 (2020).
Roczo-Farkas, S. et al. The Impact of Rotavirus Vaccines on Genotype Diversity: A Comprehensive Analysis of 2 Decades of Australian Surveillance Data. The Journal of infectious diseases 218, 546-554, doi:10.1093/infdis/jiy197 (2018).
Utsumi, T. et al. Equine-like G3 rotavirus strains as predominant strains among children in Indonesia in 2015-2016. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 61, 224-228, doi:10.1016/j.meegid.2018.03.027 (2018).
Bishop, R. F. et al. Rotavirus serotypes causing acute diarrhoea in hospitalized children in Yogyakarta, Indonesia during 1978-1979. Archives of virology 107, 207-213, doi:10.1007/BF01317917 (1989).
Urasawa, S. et al. A survey of rotavirus infection in the topics. Jpn J Med Sci Biol 34, 293-298, doi:10.7883/yoken1952.34.293 (1981).
Soenarto, Y. et al. Acute diarrhea and rotavirus infection in newborn babies and children in Yogyakarta, Indonesia, from June 1978 to June 1979. Journal of clinical microbiology 14, 123-129, doi:10.1128/JCM.14.2.123-129.1981 (1981).
Morinet, F., Ferchal, F., Colimon, R. & Perol, Y. Comparison of six methods for detecting human rotavirus in stools. Eur J Clin Microbiol 3, 136-140, doi:10.1007/BF02014331 (1984).
Rubenstein, A. S. & Miller, M. F. Comparison of an enzyme immunoassay with electron microscopic procedures for detecting rotavirus. Journal of clinical microbiology 15, 938-944, doi:10.1128/JCM.15.5.938-944.1982 (1982).
Razali, A., Jufri, A., Karo-Karo, M., Sutanto, A. H. & Siregar, H. Rotavirus gastroenteritis in Medan (Part four). Paediatr Indones 24, 145-152 (1984).
Wasito, E. B. et al. Isolation Frequency of Enteropathogens from Pediatric Diarrheal Stool in Surabaya, Indonesia: A Five Year Hospital Based Study. Japan. J. Trop. Med. Hyg. 27, 433-436 (1999).
Subekti, D. et al. Incidence of Norwalk-like viruses, rotavirus and adenovirus infection in patients with acute gastroenteritis in Jakarta, Indonesia. FEMS Immunol Med Microbiol 33, 27-33, doi:10.1111/j.1574-695X.2002.tb00568.x (2002).
Bresee, J. et al. First report from the Asian Rotavirus Surveillance Network. Emerging infectious diseases 10, 988-995, doi:10.3201/eid1006.030519 (2004).
Tjitrasari, T., Firmansyah, A. & Chair, I. Clinical manifestations of rotavirus diarrhea in the outpatient clinic of Cipto Mangunkusumo Hospital, Jakarta. Paediatrica Indonesiana 45, 69-73 (2005).
Salim, H., Karyana, I. P., Sanjaya-Putra, I. G., Budiarsa, S. & Soenarto, Y. Risk factors of rotavirus diarrhea in hospitalized children in Sanglah Hospital, Denpasar: a prospective cohort study. BMC Gastroenterol 14, 54, doi:10.1186/1471-230X-14-54 (2014).
Prasetyo, D., Sabaroedin, I. M., Ermaya, Y. S. & Soenarto, Y. Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. J Trop Med 2015, 862578, doi:10.1155/2015/862578 (2015).
Prasetyo, D., Ermaya, Y., Martiza, I. & Yati, S. Correlation between climate variations and rotavirus diarrhea in under- five children in Bandung. Asian Pac J Trop Dis 5, 908-911 (2015).
Ermaya, Y. S., Prasetyo, D., Sabaroedin, I. M. & Soenarto, Y. A Correlational study between Nutritional Status and Severity of Rotavirus Diarrhea in children under ve years in Bandung, Indonesia. Journal of GHR 6, 2490-2494 (2017).
Soenarto, Y. et al. Burden of severe rotavirus diarrhea in indonesia. The Journal of infectious diseases 200 Suppl 1, S188-194, doi:10.1086/605338 (2009).
Nelson, E. A. et al. Rotavirus epidemiology: the Asian Rotavirus Surveillance Network. Vaccine 26, 3192-3196, doi:10.1016/j.vaccine.2008.03.073 (2008).
Wilopo, S. A. et al. Rotavirus surveillance to determine disease burden and epidemiology in Java, Indonesia, August 2001 through April 2004. Vaccine 27 Suppl 5, F61-66, doi:10.1016/j.vaccine.2009.09.004 (2009).
Widowati, T., Bakrie, A., Nirwati, H. & Soenarto, Y. Surveillance of rotavirus diarrhea. Paediatrica Indonesiana 52, 22-27, doi:https://doi.org/10.14238/pi52.1.2012.22-27 (2012).
Radji, M., Putman, S. D., Malik, A., Husrima, R. & Listyaningsih, E. Molecular characterization of human group A rotavirus from stool samples in young children with diarrhea in Indonesia. The Southeast Asian journal of tropical medicine and public health 41, 341-346 (2010).
Kadim, M., Soenarto, Y., Hegar, B. & Firmansyah, A. Epidemiology of Rotavirus diarrhea in children under five: A hospital-based surveillance in Jakarta. Paediatrica Indonesiana 51, 138-143, doi:https://doi.org/10.14238/pi51.3.2011.138-43 (2011).
Parwata, W. S. S., Sukardi, W., Wahab, A. & Soenarto, Y. Prevalence and clinical characteristics of rotavirus diarrhea in Mataram, Lombok, Indonesia. Paediatrica Indonesiana 56, 118-123 (2016).
Djojosugito, F. A., Savira, M., Anggraini, D. & Putra, A. E. Identification of the P Genotypes of rotavirus in children with acute diarrhea in Pekanbaru, Indonesia. Malaysian Journal of Microbiology 13, 67-72 (2017).
Widowati, T., Mulyani, N. S., Nirwati, H. & Soenarto, Y. Diare Rotavirus pada Anak Usia Balita. Sari Pediatri 13, 340-345, doi:https://dx.doi.org/10.14238/sp13.5.2012.340-5 (2012).
Nirwati, H., Wibawa, T., Aman, A. T., Wahab, A. & Soenarto, Y. Detection of group A rotavirus strains circulating among children with acute diarrhea in Indonesia. Springerplus 5, 97, doi:10.1186/s40064-016-1724-5 (2016).
Nirwati, H. et al. Norovirus and rotavirus infections in children less than five years of age hospitalized with acute gastroenteritis in Indonesia. Archives of virology 164, 1515-1525, doi:10.1007/s00705-019-04215-y (2019).
Athiyyah, A. F. et al. Molecular Epidemiology and Clinical Features of Rotavirus Infection Among Pediatric Patients in East Java, Indonesia During 2015-2018: Dynamic Changes in Rotavirus Genotypes From Equine-Like G3 to Typical Human G1/G3. Front Microbiol 10, 940, doi:10.3389/fmicb.2019.00940 (2019).
Putnam, S. D. et al. Group A rotavirus-associated diarrhea in children seeking treatment in Indonesia. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 40, 289-294, doi:10.1016/j.jcv.2007.09.005 (2007).
Sudarmo, S. M. et al. Genotyping and clinical factors in pediatric diarrhea caused by rotaviruses: one-year surveillance in Surabaya, Indonesia. Gut Pathog 7, 3, doi:10.1186/s13099-015-0048-2 (2015).
Gdara, F. O., At Thobari, J. & Soenarto, Y. Severity and treatment level of acute gastroenteritis with rotavirus in children under 5 years in Indonesia. J Med Sci. 50, 103-112 (2018).
Mulyani, N. S. et al. Diarrhea among hospitalized children under five: A call for inclusion of rotavirus vaccine to the national immunization program in Indonesia. Vaccine 36, 7826-7831, doi:10.1016/j.vaccine.2018.05.031 (2018).
Pratiwi, E., Setiawaty, V. & Putranto, R. H. Molecular characteristics of rotavirus isolated from a diarrhea outbreak in october 2008 in bintuni bay, papua, indonesia. Virology (Auckl) 5, 11-14, doi:10.4137/VRT.S13555 (2014).
Mwenda, J. M. et al. Burden and epidemiology of rotavirus diarrhea in selected African countries: preliminary results from the African Rotavirus Surveillance Network. The Journal of infectious diseases 202 Suppl, S5-S11, doi:10.1086/653557 (2010).
Kang, G. et al. Multicenter, hospital-based surveillance of rotavirus disease and strains among indian children aged <5 years. The Journal of infectious diseases 200 Suppl 1, S147-153, doi:10.1086/605031 (2009).
Fischer, T. K. et al. Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003. The Journal of infectious diseases 195, 1117-1125, doi:10.1086/512863 (2007).
Chen, K. T. et al. Sentinel hospital surveillance for rotavirus diarrhea in Taiwan, 2001-2003. The Journal of infectious diseases 192 Suppl 1, S44-48, doi:10.1086/431495 (2005).
Bhan, M. K. et al. Protection conferred by neonatal rotavirus infection against subsequent rotavirus diarrhea. The Journal of infectious diseases 168, 282-287, doi:10.1093/infdis/168.2.282 (1993).
Bernstein, D. I., Sander, D. S., Smith, V. E., Schiff, G. M. & Ward, R. L. Protection from rotavirus reinfection: 2-year prospective study. The Journal of infectious diseases 164, 277-283, doi:10.1093/infdis/164.2.277 (1991).
Velazquez, F. R. et al. Rotavirus infection in infants as protection against subsequent infections. The New England journal of medicine 335, 1022-1028, doi:10.1056/NEJM199610033351404 (1996).
Bishop, R. Discovery of rotavirus: Implications for child health. Journal of gastroenterology and hepatology 24 Suppl 3, S81-85, doi:10.1111/j.1440-1746.2009.06076.x (2009).
Bishop, R. F. Natural history of human rotavirus infection. Archives of virology. Supplementum 12, 119-128, doi:10.1007/978-3-7091-6553-9_14 (1996).
Crawford, S. E. et al. Rotavirus infection. Nature reviews. Disease primers 3, 17083, doi:10.1038/nrdp.2017.83 (2017).
Lan, W. T. et al. Concomitant rotavirus and Salmonella infections in children with acute diarrhea. Pediatr Neonatol 50, 8-12, doi:10.1016/S1875-9572(09)60023-1 (2009).
Nirwati, H. et al. Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesia. Malays J Med Sci 24, 68-77, doi:10.21315/mjms2017.24.2.9 (2017).
Bern, C. et al. Rotavirus diarrhea in Bangladeshi children: correlation of disease severity with serotypes. Journal of clinical microbiology 30, 3234-3238, doi:10.1128/JCM.30.12.3234-3238.1992 (1992).
Scheier, E. & Aviner, S. Septicemia following rotavirus gastroenteritis. Isr Med Assoc J 15, 166-169 (2013).
Glass, R. I. et al. Rotavirus vaccines: current prospects and future challenges. Lancet 368, 323-332, doi:10.1016/S0140-6736(06)68815-6 (2006).
Lynch, M. et al. Rotavirus and central nervous system symptoms: cause or contaminant? Case reports and review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 33, 932-938, doi:10.1086/322650 (2001).
Tate, J. E. et al. 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. The Lancet. Infectious diseases 12, 136-141, doi:10.1016/S1473-3099(11)70253-5 (2012).
Kawai, K., O'Brien, M. A., Goveia, M. G., Mast, T. C. & El Khoury, A. C. Burden of rotavirus gastroenteritis and distribution of rotavirus strains in Asia: a systematic review. Vaccine 30, 1244-1254, doi:10.1016/j.vaccine.2011.12.092 (2012).
Masendycz, P., Bogdanovic-Sakran, N., Kirkwood, C., Bishop, R. & Barnes, G. Report of the Australian Rotavirus Surveillance Program, 2000/2001. Communicable diseases intelligence quarterly report 25, 143-146 (2001).
Reidy, N., O'Halloran, F., Fanning, S., Cryan, B. & O'Shea, H. Emergence of G3 and G9 rotavirus and increased incidence of mixed infections in the southern region of Ireland 2001-2004. Journal of medical virology 77, 571-578, doi:10.1002/jmv.20494 (2005).
Banerjee, I. et al. Comparative study of the epidemiology of rotavirus in children from a community-based birth cohort and a hospital in South India. Journal of clinical microbiology 44, 2468-2474, doi:10.1128/JCM.01882-05 (2006).
Durmaz, R. et al. Prevalence of rotavirus genotypes in children younger than 5 years of age before the introduction of a universal rotavirus vaccination program: report of rotavirus surveillance in Turkey. PloS one 9, e113674, doi:10.1371/journal.pone.0113674 (2014).
Bennour, H. et al. Unexpected predominance of rotavirus G9P[8] strain in Tunisian adult diarrheal patients. J Med Microbiol 69, 280-289, doi:10.1099/jmm.0.001156 (2020).
Gentsch, J. R. et al. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. The Journal of infectious diseases 192 Suppl 1, S146-159, doi:10.1086/431499 (2005).
Albert, M. J., Soenarto, Y. & Bishop, R. F. Epidemiology of rotavirus diarrhea in Yogyakarta, Indonesia, as revealed by electrophoresis of genome RNA. Journal of clinical microbiology 16, 731-733 (1982).
Esona, M. D. et al. Determination of the G and P types of previously nontypeable rotavirus strains from the African Rotavirus Network, 1996-2004: Identification of unusual G types. The Journal of infectious diseases 202 Suppl, S49-54, doi:10.1086/653552 (2010).
Angel, J., Franco, M. A. & Greenberg, H. B. Rotavirus vaccines: recent developments and future considerations. Nat Rev Microbiol 5, 529-539, doi:10.1038/nrmicro1692 (2007).
DOI: https://doi.org/10.19106/JMedSci005301202105
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