Effect of crude palm oil consumption on the levels of plasma ß-carotene, malondialdehyde and xanthine oxidase activity of healthy housewives

https://doi.org/10.19106/JMedSci005201202005

Yunita Filia Assah(1*), Shinta Wahyu Apriyani(2), Alim Mahawan Nuryadi(3), Ardi Kurniawan Makalalag(4)

(1) Industrial Research and Standardization Center of Manado, The Ministry of Industry of Republic of Indonesia
(2) Industrial Research and Standardization Center of Manado, The Ministry of Industry of Republic of Indonesia
(3) Industrial Research and Standardization Center of Manado, The Ministry of Industry of Republic of Indonesia
(4) Industrial Research and Standardization Center of Manado, The Ministry of Industry of Republic of Indonesia
(*) Corresponding Author

Abstract


Crude palm oil that contains high ß-carotenecan be obtained from mesocarp extraction of Elaesisguneensis Jacq.In the body, the ß-caroteneis converted to vitamin A that has antioxidant activity. Antioxidantscan inhibit lipid peroxidation induced by free radicals or singlet oxygen. It also inhibits the increase of reactive oxygen species (ROS) in the form of anion superoxide and hydrogen peroxide through the xanthine oxidase mechanism.This study aimed to evaluate the effect of crude palm oil consumption on the plasma ß-carotene and malondialdehyde (MDA) levels as well as xanthine oxidase activityof healthy housewives. Twenty-two healthy housewives who met the inclusion and exclusion criteria were involved in this study. Blood plasma samples were taken before and after consuming crude palm oil for two months as much as± 3.58 mL daily.The results showed that consumption of crude palm oil increased the plasma ß-carotene levels of 16 people (72%),and decreased the plasma MDAlevels of 13 people (59%).Meanwhile, thexantin oxidase enzyme activity showed no significantly different (p>0.05). Crude palm oil can increase plasma ß-carotene levels. It can be an alternative natural food source of provitamin A due to the high β-carotene content.


Keywords


Beta carotene; Crude Palm Oil; Malondialdehyde; Xanthine Oxidase; antioxidant;

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References

  1. Prasanth Kumar PK, Gopala Krishna AG. Physico-chemical characteristics and nutraceutical distribution of crude palm oil and its fractions. Grasas Y Aceites 2014; 65(652):18-35. https://doi.org/10.3989/gya.097413
  2. 2. Gunstone FD. Vegetable oils in food technology: composition, properties and uses, Second Ed.New York: Blackwell Publishing Ltd., 2011. https://doi.org/10.1002/9781444339925
  3. 3. Badan Pusat Statistik. Statistik Indonesia 2017. Jakarta: Badan Pusat Statistik, 2017.
  4. Oguntibeju OO, Esterhuyse AJ, Truter EJ. Red palm oil: nutritional, physiological and therapeutic roles in improving human wellbeing and quality of life. Br J Biomed Sci 2009; 66(4):216-22. https://doi.org/10.1080/09674845.2009.11730279
  5. Nagao A. Absorption and function of dietary carotenoids. Biofactors 2011; 37(2):83-7. https://doi.org/10.1002/biof.151
  6. Eszy MS, Sastri S, Masri M. Pengaruh pemberian diet tinggi minyak sawit terhadap kadar malondialdehid darah tikus wistar. J Kesehat Andalas 2014; 3(3):409-14.
  7. Haidari F, Keshavarz SA, Rashidi MR, Shahi MM. Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity. J Clin Biochem Nutr 2009; 45(3):285-91. https://doi.org/10.3164/jcbn.09-15
  8. Mohd Fahami NA, Ibrahim IA, Kamisah Y, Ismail NM. Palm vitamin E reduces catecholamines, xanthine oxidase activity and gastric lesions in rats exposed to water-immersion restraint stress. BMC Gastroenterol 2012; 12:54. https://doi.org/10.1186/1471-230X-12-54
  9. McIntosh WA,Zey M. Women as gatekeepers of food consumption: a sociological critique. Food Foodways 2010;3(4):317-32. https://doi.org/10.1080/07409710.1989.9961959
  10. Neeld JB Jr, Pearson WN. Macro- and micromethods for the determination serum vitamin A using trifluoroacetic acid. J Nutr 1963:454-62. https://doi.org/10.1093/jn/79.4.454
  11. Tahira R, Rehman A, Nagra SA. Comparison of serum β-carotene and retinol in smokers and non-smokers. International Journal Of Agriculture & Biology 2003; 5(4):452-4.
  12. Conti M, Morand PC, Levillain P, Lemonnier A. Improved fluorometric determination of malonaldehyde. Clin Chem 1991; 37(7):1273-5. https://doi.org/10.1093/clinchem/37.7.1273
  13. Raghuvanshi R, Kaul A, Bhakuni P, Mishra A, Misra MK. Xanthine oxidase as a marker of myocardial infarction. Indian J Clin Biochem 2007; 22(2):90-2. https://doi.org/10.1007/BF02913321
  14. Anggraeni M. Konsumsi minyak sawit merah terhadap jumlah sel natural killer dan kadar enzim siklooksigenase 2 pada limfosit ibu rumah tangga di kecamatan Dramaga Bogor [Tesis]. Bogor: Fakultas Teknologi Pertanian Institut Pertanian Bogor; 2012.
  15. Trumbo P, Yates AA, Schlicker S, Poos M. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J Am Diet Assoc 2001; 101(3):294-301. https://doi.org/10.1016/S0002-8223(01)00078-5
  16. Haskell MJ. The challenge to reach nutritional adequacy for vitamin A: β-carotene bioavailability and conversion--evidence in humans. Am J Clin Nutr 2012; 96(5):1193-1203. https://doi.org/10.3945/ajcn.112.034850
  17. 17. Novotny JA, Harrison DJ, Pawlosky R, Flanagan VP, Harrison EH, Kurilich AC. β-carotene conversion to vitamin A decreases as the dietary dose increases in humans. J Nutr 2010; 140(5):915-8. https://10.3945/jn.109.116947
  18. Perdani CG, Zakaria FR, Prangdimurti E. Pemanfaatan minyak sawit mentah sebagai hepatoprotektor pada ibu rumah tangga di Dramaga Bogor. J Teknol Pertanian 2016; 17(2):119-28. https://doi.org/10.21776/ub.jtp.2016.017.02.5
  19. Nursalim. Crude palm oil consumption was accepted and improved lipid profile and reduced c-reactive protein content in plasma of childbearing age women in sub district Dramaga Bogor [Tesis]. Bogor: Fakultas Teknologi Pertanian, Institut Pertanian Bogor. 2012.
  20. Weber D, Grune T. The contribution of β-carotene to vitamin A supply of humans. Mol Nutr Food Res 2012; 56(2):251-8. http://doi.org/10.1002/mnfr.201100230
  21. 21. Mukherjee S, Mitra A. Health effects of palm oil. J Hum Ecol 2009; 26(3):197-203. https://doi.org/10.1080/09709274.2009.11906182
  22. Budin SB, Yusof KM, Idris MHM, Hamid ZA, Mohamed J. Tocotrienol-rich fraction of palm oil reduced pancreatic damage and oxidative stress in streptozotocin-induced diabetic rats. Aust J Basic Appl Sci 2011; 5(12):2367-74.
  23. Eidangbe GO, Ojieh GC, Idonije BO, Oluba OM. Palm oil and egusi melon oil lower serum and liver lipid profile and improve antioxidant activity in rats fed a high fat diet. J Food Technol 2010; 8(4):154-8. https://doi.org/10.3923/jftech.2010.154.158
  24. Torun AN, Kulaksizoglu S, Kulaksizoglu M, Pamuk BO, Isbilen E, Tutuncu NB. Serum total antioxidant status and lipid peroxidation marker malondialdehyde levels in overt and subclinical hypothyroidism. Clin Endocrinol (Oxf) 2009; 70(3):469-74. https://doi.org/10.1111/j.1365-2265.2008.03348.x
  25. Fiedor J, Burda K. Potential role of carotenoids as antioxidants in human health and disease. Nutrients 2014; 6(2):466-88. https://doi.org/10.3390/nu6020466
  26. Zhang JW, Lv GC, Zhao Y. The significance of the measurement of serum xanthine oxidase and oxidation markers in patients with acute organophosphorus pesticide poisoning. J Int Med Res 2010; 38(2):458-65. https://doi.org/10.1177/147323001003800209
  27. Weidinger A, Kozlov AV. Biological activities of reactive oxygen and nitrogen species: oxidative stress versus signal transduction. Biomolecules 2015;5(2):472-84. https://doi.org/10.3390/biom5020472
  28. Newaz MA, Adeeb NN. Detection of xanthine oxidase in human plasma. Med J Malaysia 1998; 53(1):70-5.



DOI: https://doi.org/10.19106/JMedSci005201202005

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