* Corresponding Author
The role of virulence factors inCandida albicanspathogenicity
https://doi.org/10.19106/JMedSci004801201606 Tri Wibawa(1*)
(1) Department of Microbiology, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia
(*) Corresponding Author
Abstract
Candida albicans is a classical example of causative agent for opportunistic fungal
infection. Normally, it colonizes skin, gastrointestinal tract, genital, and mucosal
membranes, but in certain condition it may responsible for diseases. This phenomenon
was mainly associated with immunological status of the host. However, there were
findings that showed the possibility of putative virulence factors work on the transition
of commensally to pathogenic role of the yeast. In this review, some virulence factors
were discussed. Indeed, there were factors that may be considered as putative virulence
factors of C. albicans.
infection. Normally, it colonizes skin, gastrointestinal tract, genital, and mucosal
membranes, but in certain condition it may responsible for diseases. This phenomenon
was mainly associated with immunological status of the host. However, there were
findings that showed the possibility of putative virulence factors work on the transition
of commensally to pathogenic role of the yeast. In this review, some virulence factors
were discussed. Indeed, there were factors that may be considered as putative virulence
factors of C. albicans.
Keywords
Candida albicans – opportunistic infection – fungal – pathogenicity - virulence
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PDF DOI: https://doi.org/10.19106/JMedSci004801201606
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