MUCOLYTIC IN VITRO ACTIVITY OF ETHANOLIC EXTRACT OF Hibiscus rosa-sinensis L. RED STRAIGHT CROWN
Dinar Hesti Permatasari(1), Mimiek Murrukmihadi(2*)
(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author
Abstract
Ethanolic extract of red shoe flower (Hibiscus rosa-sinensis L.) has been known to decrease mucus viscosity by in vitro. The aim of this study is to evaluate the effect of various concentration of the extract in syrup for decreasing mucus viscosity and to evaluate the extract concentration which is equal with asetilsistein syrup 2.00%. Ethanolic extract was produced by maseration and made into five different concentration of syrup formula (1.00; 1.25; 1.50; 1.75 and 2.00%). The result showed that there is not any mucolytic activity from all of the formulas by decreasing mucus viscosity and there is not any formula as effective as mucolytic activity of asetilsistein 2.00%.
Keywords
Full Text:
pdf (Bahasa Indonesia)References
Anonim. 1985. Tanaman Obat Indonesia, Jilid I, Departemen Kesehatan Republik Indonesia, Jakarta
Anonim. 2009. Getting Started with v8 of Design-Expert® Software, http://www.statease.com/, diakses tanggal 9 Mei 2011
Fitria, A. 2009. Isolasi dan Identifikasi Senyawa Alkaloid Ekstrak Etanolik Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.), Skripsi, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta
Heyne, K. 1950. Tumbuhan Berguna Indonesia, diterjemahkan oleh Badan Litbang Kehutanan, Jilid Ketiga, Cetakan Pertama, Yayasan Sarana Wana Jaya, Jakarta. pp 1309
Hidayati, R. 2010. Optimasi Formulasi Sirup Fraksi Alkaloid Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.) Warna Merah, Skripsi, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta
Lande, S.Y. 2009. Aktivitas Mukolitik Ekstrak Etanolik Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.) pada Mukus Usus Sapi secara In Vitro dengan Viskometer Ostwald, Skripsi, Fakultas Farmasi Universitas Gadjah Mada Yogyakarta
DOI: https://doi.org/10.22146/tradmedj.7749
Article Metrics
Abstract views : 1628 | views : 6570Refbacks
- There are currently no refbacks.
Copyright (c) 2015 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada