MUCOLYTIC IN VITRO ACTIVITY OF ETHANOLIC EXTRACT OF Hibiscus rosa-sinensis L. RED STRAIGHT CROWN

https://doi.org/10.22146/tradmedj.7749

Dinar Hesti Permatasari(1), Mimiek Murrukmihadi(2*)

(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Ethanolic extract of red shoe flower (Hibiscus rosa-sinensis L.) has been known to decrease mucus viscosity by in vitro. The aim of this study is to evaluate the effect of various concentration of the extract in syrup for decreasing mucus viscosity and to evaluate the extract concentration which is equal with asetilsistein syrup 2.00%. Ethanolic extract was produced by maseration and made into five different concentration of syrup formula (1.00; 1.25; 1.50; 1.75 and 2.00%). The result showed that there is not any mucolytic activity from all of the formulas by decreasing mucus viscosity and there is not any formula as effective as mucolytic activity of asetilsistein 2.00%.


Keywords


mucolytic, syrup, ethanolic extract, red shoe flower



References

Anonim. 1985. Tanaman Obat Indonesia, Jilid I, Departemen Kesehatan Republik Indonesia, Jakarta

Anonim. 2009. Getting Started with v8 of Design-Expert® Software, http://www.statease.com/, diakses tanggal 9 Mei 2011

Fitria, A. 2009. Isolasi dan Identifikasi Senyawa Alkaloid Ekstrak Etanolik Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.), Skripsi, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta

Heyne, K. 1950. Tumbuhan Berguna Indonesia, diterjemahkan oleh Badan Litbang Kehutanan, Jilid Ketiga, Cetakan Pertama, Yayasan Sarana Wana Jaya, Jakarta. pp 1309

Hidayati, R. 2010. Optimasi Formulasi Sirup Fraksi Alkaloid Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.) Warna Merah, Skripsi, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta

Lande, S.Y. 2009. Aktivitas Mukolitik Ekstrak Etanolik Bunga Kembang Sepatu (Hibiscus rosa-sinensis L.) pada Mukus Usus Sapi secara In Vitro dengan Viskometer Ostwald, Skripsi, Fakultas Farmasi Universitas Gadjah Mada Yogyakarta



DOI: https://doi.org/10.22146/tradmedj.7749

Article Metrics

Abstract views : 1669 | views : 6626

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2015 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada