.png)
.png)
* Corresponding Author
Phytochemical Quantification and Efficacy of Persea Americana Extracts on some Selected Pathogens
https://doi.org/10.22146/mot.74687 Sunday Olusegun Oladoye(1), Victoria Adeola Falade(2*), Adewusi John Adepoju(3), Geshin John Ibikunle(4)
(1) Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, P.M.B. 4000
(2) Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, P.M.B. 4000
(3) Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, P.M.B. 4000
(4) Department of Science Laboratory Technology, Ladoke Akintola University of Technology, P.M.B. 4000. Ogbomoso
(*) Corresponding Author
Abstract
Medicinal and aromatic plants are increasingly becoming the focus of many researchers in the search for alternative antimicrobial agents due to their large number of diverse bioactive compounds called phytochemicals. Persea americana (Avocado) is an evergreen tree plant known for its healthy fruit and has been used in the management of disease and infections. The stem bark of P. americana was investigated for its phyto-constituents and antimicrobial activity using standard methods. The stem bark was preponderant in polyphenolic compounds of which flavonoid was found to be abundant (480.01), the antimicrobial activity study of the extracts also showed good inhibitory activity on all the tested strains with K. oxytoca (27.50 ± 0.67 mm) and A. flavus (88.89%) mostly susceptible in a concentration-dependent manner. The study revealed that P. americana extracts could be explored in the search for alternative antimicrobial agents.
Keywords
Full Text:
PDFReferences
Arpita Roy, 2017. A Review on the Alkaloids an Important Therapeutic Compound from Plants. International Journal of Plant Biotechnology, 3 (2), 1–9.
Bertin, J., Zoa, A., Ngono, R., and Abondo, M., 2020. Micrography, phyto-chemical screening and physico-chemical properties of Bridelia micrantha (Hochst.) Baill. and Persea americana L. stem bark. Journal of Pharmacognosy and Phytochemistry, 9 (3), 32–36.
Ejiofor, N. C., Ezeagu, I. E., Ayoola, M. B., and Umera, E. A., 2018. Determination of the Chemical Composition of Avocado (Persea americana) Seed. Advances in Food Technology and Nutritional Sciences - Open Journal, SE (2), S51–S55. DOI: 10.17140/aftnsoj-se-2-107
Falodun, A., Iyamabo, H., Odion, E., and Engel-Lutz, N., 2013. Antiproliferative and Pro-apoptotic activities of the stem bark of Persea americana (lauraceae) mill in Human Breast Adenocarcinoma Cell Line. Journal of Applied Sciences and Environmental Management, 17 (3), 433–438. DOI: 10.4314/jasem.v17i3.13
Guclu-Ustundag, Ö., and Mazza, G., 2007. Saponins: Properties, applications, and processing. Critical Reviews in Food Science and Nutrition, 47 (3), 231–258. DOI: 10.1080/10408390600698197
Harborne, J. B., 1998. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. Phytochemical Methods. London New York: Chapman and Hall Ltd. DOI: 10.1007/978-94-009-5921-7
Karak, P., 2019. Biological Activities of Flavonoids: An Overview. International Journal of Pharmaceutical Sciences and Research, 10 (4), 1567–1574. DOI: 10.13040/IJPSR.0975-8232.10(4).1567-74
Kumar, S., and Pandey, A. K., 2013. Chemistry and biological activities of flavonoids: An overview. The Scientific World Journal, 2013 (162750), 1–16. DOI: 10.1155/2013/162750
Lateef, A., Akande, M. A., Ojo, S. A., Folarin, B. I., Gueguim-Kana, E. B., and Beukes, L. S., 2016. Paper wasp nest-mediated biosynthesis of silver nanoparticles for antimicrobial, catalytic, anticoagulant, and thrombolytic applications. 3 Biotech, 6 (140), 1–10. Springer Berlin Heidelberg. DOI: 10.1007/s13205-016-0459-x
Mallaiah, P., Sudhakara, G., Srinivasulu, N., Sasi Bhusana Rao, B., Vijayabharathi, G., and Saralakumari, D., 2015. Assessment of in vitro antioxidant potential and quantification of total phenols and flavonoids of aqueous extract of Phyllanthus amarus. International Journal of Pharmacy and Pharmaceutical Sciences, 7 (9), 439–445.
Minatel, I. O., Borges, C. V., Ferreira, M. I., Gomez, H. A. G., Chen, C. O., and Lima, G. P. P., 2017. Phenolic Compounds: Functional Properties, Impact of Processing, and Bioavailability. In M. Soto-Hernandez, M. Palma-Tenango, and M. D. R. Garcia-Mateos (Eds.), Phenolic Compounds - Biological Activity (pp. 1–25). IntechOpen. DOI: 10.5772/66368
Moldoveanu, S. C., and David, V., 2013. Mobile Phases and Their Properties. In S. C. Moldoveanu and V. David (Eds.), Essentials in Modern HPLC Separations (pp. 363–447). Elsevier Inc. DOI: 10.1016/b978-0-12-385013-3.00007-0
Nguyen, V. T., Pham, H. N. T., Bowyer, M. C., Van Altena, I. A., and Scarlett, C. J., 2016. Influence of solvents and novel extraction methods on bioactive compounds and antioxidant capacity of Phyllanthus amarus. Chemical Papers, 70 (5), 556–566. DOI: 10.1515/chempap-2015-0240
Obadoni, B. O., and Ochuko, P. O., 2002. Phytochemical Studies And Comparative Efficacy of The Crude Extracts of Some Haemostatic Plants In Edo And Delta States of Nigeria. Global Journal of Pure and Applied Sciences, 8 (2), 203–208. DOI: 10.4314/gjpas.v8i2.16033
Osuntokun, T. O., Akinola, M., Aladejana, O., and Ogunlade, A., 2017. Efficacy of Essential Oils from Persea americana Stem Bark and Seed Extracts. Journal of Applied Microbiology and Biochemistry, 2 (8), 1–6. DOI: 10.21767/2576-1412.100012
Park, S. J., Nam, Y. H., Rodriguez, I., Park, J. H., Kwak, H. J., Oh, Y., Oh, M., et al., 2019. Chemical constituents of leaves of Persea americana (avocado) and their protective effects against neomycin-induced hair cell damage. Revista Brasileira de Farmacognosia, 29 (6), 739–743. Sociedade Brasileira de Farmacognosia. DOI: 10.1016/j.bjp.2019.08.004
Soniya, M., Kuberan, T., Anitha, S., and Sankareswari, P., 2013. In vitro antibacterial activity of plant extracts against Gram-positive and Gram-negative pathogenic bacteria. International Journal of Microbiology and Immunology Research, 2 (1), 1–5.
Tambe, V. D., and Bhambar, R. S., 2014. Estimation of Total Phenol, Tannin, Alkaloid, and Flavonoid in Hibiscus tiliaceus Linn. Wood Extracts. Research and Reviews: Journal of Pharmacognosy and Phytochemistry, 2 (4), 41–47.
Zain, S. N. D. M., and Omar, W. A. W., 2018. Antioxidant activity, total phenolic content, and total flavonoid content of water and methanol extracts of Phyllanthus species from Malaysia. Pharmacognosy Journal, 10 (4), 677–681. DOI: 10.5530/pj.2018.4.111
DOI: https://doi.org/10.22146/mot.74687
Article Metrics
Abstract views : 1465
| 
views : 1058
Refbacks
- There are currently no refbacks.
Copyright (c) 2022 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada