Antibacterial activity of Laja Gowah (Alpinia malaccensis (Brum.f) Roscoe) oil in Reducing the Number of Staphylococcus aureus Colonies in Hospital Wards

https://doi.org/10.22146/mot.68323

Khoirun Nisyak(1*)

(1) STIKES Rumah Sakit Anwar Medika, Sidoarjo, Jawa Timur
(*) Corresponding Author

Abstract


Staphylococcus aureus is one of the pathogenic bacteria that cause nosocomial infections in hospitals. The use of essential oil-based antibacterials for hospital wards was developed to prevent nosocomial infections. Laja gowah oil is an essential oil isolated from the Alpinia malaccensis plant, which belongs to the Zingiberaceae plant group. The purpose of this study was to determine the antibacterial activity of laja gowah oil in reducing the number of S. aureus colonies in hospital inpatient rooms through the air diffusion method. The compound content in laja gowah oil was analyzed with GC-MS. The study of antibacterial activity using the total plant counts continued with the colony count test, Gram staining, catalase test, and coagulase test. Laja gowah oil contains methyl cinnamate and 1,8-cineole. The installation time of the diffuser containing laja gowah oil affects the number of colonies of S. aureus bacteria in hospital wards. The antibacterial activity of laja gowah oil was influenced by the synergistic effect of methyl cinnamate and 1,8-cineole compounds.


Keywords


laja gowah; Staphylococcus aureus; nosocomial infection; hospital wards; diffuser essential oil

Full Text:

PDF


References

Bazargani, M. M., & Rohloff, J. (2016). Antibiofilm activity of essential oils and plant extracts against Staphylococcus aureus and Escherichia coli biofilms. Food Control, 61, 156–164. https://doi.org/10.1016/j.foodcont.2015.09.036

Clausen, P. A., Frederiksen, M., Sejbæk, C. S., Sørli, J. B., Hougaard, K. S., Frydendall, K. B., Wolkoff, P. (2020). Chemicals inhaled from spray cleaning and disinfection products and their respiratory effects. A comprehensive review. International Journal of Hygiene and Environmental Health, 229. https://doi.org/10.1016/j.ijheh.2020.113592

Coté, H., Boucher, M. A., Pichette, A., Roger, B., & Legault, J. (2016). New antibacterial hydrophobic assay reveals Abies balsamea oleoresin activity against Staphylococcus aureus and MRSA. Journal of Ethnopharmacology, 194(February), 684–689. https://doi.org/10.1016/j.jep.2016.10.035

Ebani, V., Nardoni, S., Bertelloni, F., Najar, B., Pistelli, L., & Mancianti, F. (2017). Antibacterial and Antifungal Activity of Essential Oils against Pathogens Responsible for Otitis Externa in Dogs and Cats. Medicines, 4(2), 21. https://doi.org/10.3390/medicines4020021

Ernawati, T., Budiana, A., & Ernawati, T. (2016). Bioaktivitas Turunan Metil Sinamat Terhadap Pertumbuhan Bakteri Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aureugenosa dan Jamur Candida albicans. Jurnal Kimia VALENSI, 1(1), 60–64. https://doi.org/10.15408/jkv.v0i0.3154

Guo, J., & Li, C. (2019). Molecular epidemiology and decreased susceptibility to disinfectants in carbapenem-resistant Acinetobacter baumannii isolated from intensive care unit patients in central China. Journal of Infection and Public Health, 12(6), 890–896. https://doi.org/10.1016/j.jiph.2019.06.007

Hendry, E. R., Worthington, T., Conway, B. R., & Lambert, P. A. (2009). Antimicrobial efficacy of eucalyptus oil and 1,8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and biofilm cultures. Journal of Antimicrobial Chemotherapy, 64(6), 1219–1225. https://doi.org/10.1093/jac/dkp362

Hidayati, L., Hadi, U. K., & Soviana, S. (2017). Kejadian Demam Berdarah Dengue di Kota Sukabumi Berdasarkan Kondisi Iklim. 5(1), 22–28.

Horváth, G., Farkas, Á., Papp, N., Bencsik, T., Ács, K., Gyergyák, K., & Kocsis, B. (2016). Natural Substances from Higher Plants as Potential Anti-MRSA Agents. In Studies in Natural Products Chemistry (Vol. 47). https://doi.org/10.1016/B978-0-444-63603-4.00003-6

Huang, Q. S., Zhu, Y. J., Li, H. L., Zhuang, J. X., Zhang, C. Le, Zhou, J. J., … Chen, Q. X. (2009). Inhibitory effects of methyl trans-cinnamate on mushroom tyrosinase and its antimicrobial activities. Journal of Agricultural and Food Chemistry, 57(6), 2565–2569. https://doi.org/10.1021/jf8036227

Hugentober, W. (2018). HUMIDITY HUMIDITY AND HEALTH Respiratory infections – a problem of our own making.

Imaniar, E., Apriliana, E., & Prambudi, R. (2011). Kualitas Mikrobiologi Udara di Inkubator Unit Perinatologi Rumah Sakit Umum Daerah Dr. Abdul Moeloek Bandar Lampung. Medical Journal of Lampung University, (ISSN 2337-3776), 51–60.

Kemenkes. (2016). Persyaratan Teknik Bangunan dan Prasarana Rumah Sakit. 1–211.

Khan, H. A., Baig, F. K., & Mehboob, R. (2017). Nosocomial infections: Epidemiology, prevention, control, and surveillance. Asian Pacific Journal of Tropical Biomedicine, 7(5), 478–482. https://doi.org/10.1016/j.apjtb.2017.01.019

Li, L., Li, Z. W., Yin, Z. Q., Wei, Q., Jia, R. Y., Zhou, L. J., … Yu, W. (2014). Antibacterial activity of leaf essential oil and its constituents from Cinnamomum longepaniculatum. International Journal of Clinical and Experimental Medicine, 7(7), 1721–1727.

Nisyak, K., & Hartiningsih, S. (2020). Aktivitas Antibakteri Minyak Serai Dapur Dan Minyak Adas Pada Staphylococcus aureus Di Ruang Rawat Inap Rumah Sakit. Jurnal Tumbuhan Obat Indonesia. 13(2), 61–69.

Padalia, R. C., Verma, R. S., Chauhan, A., Goswami, P., Singh, V. R., Verma, S. K.,Chanotiya, C. S. (2017). Essential oil composition and antimicrobial activity of methyl cinnamate-linalool chemovariant of Ocimum basilicum L. from India. Records of Natural Products, 11(2), 193–204.

Riyanto, A., Yunilawati, R., & Nuraeni, C. (2012). Isolasi Metil Sinamat dari Minyak Atsiri Laja Gowah (Alpinia malaccensis (Burm.f.)). Jurnal Kimia Dan Kemasan, 34(2), 237. https://doi.org/10.24817/jkk.v34i2.1859

Sitorus, P., & Satria, D. (2016). Antibacterial activity of ethanol extract and volatile oil of Laja Gowah rhizome (Alpinia malaccensis Burm.F.) roscoe) against Staphylococcus Aureus and Escherichia coli. Asian Journal of Pharmaceutical and Clinical Research, 9(2), 342–344.

Suyono. (2015). Analisis Regresi Untuk Penelitian (1st ed.). Yogyakarta: Deepublish.

Tselebonis, A., Nena, E., Panopoulou, M., Kontogiorgis, C., Bezirtzoglou, E., & Constantinidis, T. (2020). Air contamination in different departments of a tertiary hospital. Assessment of microbial load and antimicrobial susceptibility. Biomedicines, 8(6), 1–9. https://doi.org/10.3390/BIOMEDICINES8060163

Wikansari, N. (2012). Pemeriksaan Total Kuman Udara Dan Staphylococcus aureus Di Ruang Rawat Inap Rumah Sakit X Kota Semarang. Jurnal Kesehatan Masyarakat Universitas Diponegoro, 1(2), 18795.



DOI: https://doi.org/10.22146/mot.68323

Article Metrics

Abstract views : 2034 | views : 2630

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2021 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada