Healthcare Professionals’ Attitudes towards Adverse Drug Reactions Reporting in Primary Healthcare Settings: A Cross-sectional Survey
Cindra Tri Yuniar(1*), Rizka Zu Fadhilah(2), Kusnandar Anggadiredja(3), Lia Amalia(4)
(1) Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Jl. Ganesha 10, Bandung, West Java
(2) Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Jl. Ganesha 10, Bandung, West Java
(3) Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Jl. Ganesha 10, Bandung, West Java
(4) Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Jl. Ganesha 10, Bandung, West Java
(*) Corresponding Author
Abstract
Background: Spontaneous Adverse Drug Reactions (ADRs) reporting is a key to improving the post-marketing safety of medicines. The important factor of under-reporting is lack of awareness for the purpose of ADRs monitoring and reporting. Spontaneous reporting is performed by the patients or consumer to the healthcare professionals and/or industry, then the healthcare facilities and industry should report the suspected ADRs to the National Agency of Drugs and Food Control (NADFC). To date, there is a lack information and study about attitudes on ADRs reporting by healthcare professionals (HCPs), especially in primary healthcare settings.
Objectives: The aim of this study was to identify the attitudes towards ADRs reporting by healthcare professionals (HCP).
Methods: This research was survey study with cross-sectional design, from November 2022-March 2023. The questionnaire, that have been validated and reliable, was distributed to 3 primary healthcare facilities. demographic data questions (6 items), experiences (3 items), knowledge (4 items), and motives for reporting (1 item).
Results: Total 39 HCPs completed the survey, including 14 nurses, 9 midwifes, 3 general physicians, 3 pharmacists, and 10 other professions. Most of respondents were women (84.6%), and mostly the HCPs have been working for ≥5 years (74.3%). Among 39 respondents, only 1 pharmacist have a good attitude about ADRs reporting. The other HCPs had a lack of knowledge and safety awareness. The dominant motives for reporting the ADRs was serious or severe ADRs (39.4%) and the assurance of causality assessment by suspected drugs (15.4%).
Conclusion: In conclusion, the HCPs in primary healthcare settings had poor attitudes towards ADRs reporting.
Keywords
Full Text:
PDFReferences
- Edwards. I Ralph, Aronson JK. ADR definition. The Lancet. 2000;356:1255-1259. doi:https://doi.org/10.1016/S0140-6736(00)02799-9
- Sultana J, Cutroneo P, Trifirò G. Clinical and economic burden of adverse drug reactions. J Pharmacol Pharmacother. 2013;4(SUPPL.1). doi:10.4103/0976-500X.120957
- Dubrall D, Just KS, Schmid M, Stingl JC, Sachs B. Adverse drug reactions in older adults: A retrospective comparative analysis of spontaneous reports to the German Federal Institute for Drugs and Medical Devices. BMC Pharmacol Toxicol. 2020;21(1). doi:10.1186/s40360-020-0392-9
- Kennedy D, Goldman S, Lillie R. Spontaneous reporting in the United States. In: Pharmacoepidemiology. 3rd ed. John WIley&Sons; 2000:151-174.
- Paudyal V, Al-Hamid A, Bowen M, et al. Interventions to improve spontaneous adverse drug reaction reporting by healthcare professionals and patients: systematic review and meta-analysis. Expert Opin Drug Saf. 2020;19(9):1173-1191. doi:10.1080/14740338.2020.1807003
- Hazell L, Shakir SAW. Under-Reporting of Adverse Drug Reactions A Systematic Review. Vol 29.; 2006.
- BPOM RI. Pedoman Monitoring Efek Samping Obat (Meso) Bagi Tenaga Kesehatan.; 2012.
- Musdar TA, Nadhafi MT, Lestiono L, Lichijati L, Athiyah U, Nita Y. Faktor yang Mempengaruhi Praktik Pelaporan Adverse Drug Reactions (ADRs) oleh Apoteker di Beberapa Rumah Sakit di Surabaya. JPSCR: Journal of Pharmaceutical Science and Clinical Research. 2021;6(2):96. doi:10.20961/jpscr.v6i2.49794
- Hussain R, Akram T, Hassali MA, et al. Barriers and facilitators to pharmacovigilance activities in Pakistan: A healthcare professionals-based survey. PLoS One. 2022;17(7 July). doi:10.1371/journal.pone.0271587
- Hussain R, Hassali MA, Hashmi F, Akram T. Exploring healthcare professionals’ knowledge, attitude, and practices towards pharmacovigilance: a cross-sectional survey. J Pharm Policy Pract. 2021;14(1). doi:10.1186/s40545-020-00287-3
- Gidey K, Seifu M, Hailu BY, Asgedom SW, Niriayo YL. Healthcare professionals knowledge, attitude and practice of adverse drug reactions reporting in Ethiopia: A cross-sectional study. BMJ Open. 2020;10(2). doi:10.1136/bmjopen-2019-034553
- Sendekie AK, Netere AK, Tesfaye S, Dagnew EM, Belachew EA. Incidence and patterns of adverse drug reactions among adult patients hospitalized in the University of Gondar comprehensive specialized hospital: A prospective observational follow-up study. PLoS One. 2023;18(2 February). doi:10.1371/journal.pone.0282096
- Tagne JF, Yakob RA, Dang TH, McDonald R, Wickramasinghe N. Reporting, Monitoring, and Handling of Adverse Drug Reactions in Australia: Scoping Review. JMIR Public Health Surveill. 2023;9. doi:10.2196/40080
- Thilini Madhushika M, Jayasinghe SS, Liyanage PGC, Dilan Malinda WA, Abeykoon P. Knowledge, Attitudes, and Practices of Adverse Drug Reaction Reporting Among Healthcare Professionals in Sri Lanka- A Cross Sectional Study. Hosp Pharm. Published online 2023. doi:10.1177/00185787231194988
- Srisuriyachanchai W, Cox AR, Jarernsiripornkul N. Exploring Healthcare Professionals’ Practices and Attitudes towards Monitoring and Reporting of Severe Adverse Drug Reactions. Healthcare (Switzerland). 2022;10(6). doi:10.3390/healthcare10061077
- John LJ, Arifulla M, Cheriathu JJ, Sreedharan J. Reporting of adverse drug reactions: An exploratory study among nurses in a teaching hospital, Ajman, United Arab Emirates. DARU, Journal of Pharmaceutical Sciences. 2012;20(1). doi:10.1186/2008-2231-20-44
- Adisa R, Omitogun TI. Awareness, knowledge, attitude and practice of adverse drug reaction reporting among health workers and patients in selected primary healthcare centres in Ibadan, southwestern Nigeria. BMC Health Serv Res. 2019;19(1). doi:10.1186/s12913-019-4775-9
- Al-worafi YM. Knowledge, Attitude and Practice of Yemeni Physicians Toward Pharmacovigilance: A Mixed Method Study. Int J Pharm Pharm Sci. 2018;10(10):74. doi:10.22159/ijpps.2018v10i10.27407
- Güner MD, Ekmekci PE. Healthcare professionals’ pharmacovigilance knowledge and adverse drug reaction reporting behavior and factors determining the reporting rates. J Drug Assess. 2019;8(1):13-20. doi:10.1080/21556660.2019.1566137
- Kc S, Tragulpiankit P, Gorsanan S, Edwards IR. Attitudes among healthcare professionals to the reporting of adverse drug reactions in Nepal. BMC Pharmacol Toxicol. 2013;14. doi:10.1186/2050-6511-14-16
- Almandil NB. Healthcare professionals’ awareness and knowledge of adverse drug reactions and pharmacovigilance. Saudi Med J. 2016;37(12):1350-1355. doi:10.15537/smj.2016.12.17059
DOI: https://doi.org/10.22146/jmpf.87108
Article Metrics
Abstract views : 797 | views : 807Refbacks
- There are currently no refbacks.
Copyright (c) 2024 JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.