Measurement of Medication Adherence Behavior in Type 2 Diabetes Mellitus Patients Using Probabilistic Medication Adherence Scale (ProMAS)

https://doi.org/10.22146/jmpf.84431

Dini Ayu Rahmawati(1), Anna Wahyuni Widayanti(2*), Susi Ari Kristina(3)

(1) Magister Management Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada
(2) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada
(3) Departement of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Diabetes mellitus is a chronic disease that requires long-term treatment, which affects medication adherence. Adherence measurement can be done using a questionnaire like the Probabilistic Medication Adherence Scale (ProMAS). This study aims to determine the relationship between demographic factors and medication adherence scores in patients with diabetes mellitus. The research uses a quantitative research approach with a cross-sectional design. The convenience sampling method was used to select 112 respondents between January and April 2023 at various primary healthcare facilities in the Special Region of Yogyakarta. The ProMAS scoring results were based on the highest rankings, with 42.8% of respondents having a moderate-to-high adherence level, 41.1% of respondents having a high adherence level, 15.2% of respondents having a moderate-low adherence level, and 0.9% of respondents having a low adherence level. Diabetes mellitus patients in Yogyakarta show a high level of medication adherence. The most frequent non-adherent behavior was found in 4 questions: respondents forgot to take or inject medication (61.61%); respondents took or injected medication (one of them) slower than usual schedule (55.36%); respondents did not always take or inject medication at the same time every day (62.5%); and respondents forgot to take or inject medication at least once in the past month (58.04%). The statistical analysis indicates no relationship between demographic characteristics, the total number of medications, and the total frequency of medication with adherence levels. This indicates that diabetes mellitus patients with low or high adherence levels are unaffected by the above factors.


Keywords


Diabetes Mellitus; Medication Adherence; Probabilistic Medication Adherence Scale

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References

  1. Nathan, M.D. DM, Barrett- Connor, M.D. E, Crandall, M.D. JP, et al. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study. The Lancet Diabetes & Endocrinology. 2015;3(11):866-875. doi:10.1016/S2213-8587(15)00291-0
  2. Kementrian Kesehatan RI. Hasil Utama Riskesdas 2018. Published online 2018. https://www.kemkes.go.id/resources/download/info-terkini/hasil-riskesdas-2018.pdf25
  3. Krska J, Morecroft CW, Rowe PH, Poole H. Measuring the impact of long-term medicines use from the patient perspective. Published online 2014:4.
  4. Alfian SD, Sukandar H, Lestari K, Abdulah R. Medication Adherence Contributes to an Improved Quality of Life in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study. Diabetes Ther. 2016;7(4):755-764. doi:10.1007/s13300-016-0203-x
  5. Alfian S, Sukandar H, Arisanti N, Abdulah R. Complementary and Alternative Medicine Use Decreases Adherence to Prescribed Medication in Diabetes Patients. Ann Trop Med Public Health. 2016;9(3):174. doi:10.4103/1755-6783.179108
  6. Ratnasari PMD, Yani KLPA, Arini HD. Analysis Between the Number of Antihypertensive with Medication Adherence in End Stage Renal Disease. JFSP. Published online April 29, 2022:78-89. doi:10.31603/pharmacy.v8i1.5611
  7. Widayanti AW, Norris P, Heydon S, Green JA. Medicine Taking Behaviours of People with Type 2 Diabetes in Indonesia: A Qualitative Study. Int J Clin Pharm. 2020;42(1):31-39. doi:10.1007/s11096-019-00933-0
  8. Srikartika VM, Cahya AD, Hardiati RSW. Analisis Faktor Yang Memengaruhi Kepatuhan Penggunaan Obat Pasien Diabetes Melitus Tipe 2. 2016;6.
  9. Chan AHY, Horne R, Hankins M, Chisari C. The Medication Adherence Report Scale: A measurement tool for eliciting patients’ reports of nonadherence. Brit J Clinical Pharma. 2020;86(7):1281-1288. doi:10.1111/bcp.14193
  10. Tandon S, Chew M, Eklu-Gadegbeku CK, Shermock KM, Morisky DE. Validation and psychometric properties of the 8-item Morisky Medication Adherence Scale (MMAS-8) in Type 2 diabetes patients in sub-Saharan Africa. Diabetes Research and Clinical Practice. 2015;110(2):129-136. doi:10.1016/j.diabres.2015.10.001
  11. Kripalani S, Risser J, Gatti ME, Jacobson TA. Development and Evaluation of the Adherence to Refills and Medications Scale (ARMS) among Low-Literacy Patients with Chronic Disease. Value in Health. 2009;12(1):118-123. doi:10.1111/j.1524-4733.2008.00400.x
  12. Lam WY, Fresco P. Medication Adherence Measures: An Overview. BioMed Research International. 2015;2015:1-12. doi:10.1155/2015/217047
  13. Vluggen S, Hoving C, Schaper NC, De Vries H. Psychological predictors of adherence to oral hypoglycaemic agents: an application of the ProMAS questionnaire. Psychology & Health. 2020;35(4):387-404. doi:10.1080/08870446.2019.1672873
  14. Ratnasari PMD, Ardeliani IGAI, Yuliawati AN, Kurnianta PDM. Association Between Antidiabetic Pattern with Medication Adherence in Type 2 Diabetes Patients at Buleleng Hospital: Hubungan Antara Pola Penggunaan Antidiabetik dengan Kepatuhan Pengobatan Pada Pasien Diabetes Melitus Tipe 2 Di Salah Satu Rumah Sakit Swasta Buleleng Bali. JFG. Published online May 16, 2023. doi:10.22487/j24428744..v.i.15908
  15. Kleppe M, Lacroix J, Ham J, Midden C. The Development of the Promas: A Probabilistic Medication Adherence Scale. PPA. Published online March 2015:355. doi:10.2147/PPA.S76749
  16. Widayanti AW, Heydon S, Green JA, Norris P. Effectiveness of an Intensive Community-Based Intervention for People with Type 2 Diabetes in Indonesia: A Pilot Study. Diabetes Research and Clinical Practice. 2021;181. doi:10.1016/j.diabres.2021.109087
  17. Malina R, Yasin NM, Wiedyaningsih C. The Effect of Based Services Medication Therapy Management on Treatment Adherence and Quality of Life of Diabetes Mellitus Patients. J Manaj dan Pelayanan Farm. 2020;10(3):204. doi:10.22146/jmpf.58052
  18. Pahlawati A, Nugroho PS. Hubungan Tingkat Pendidikan dan Usia dengan Kejadian Diabetes Melitus di Wilayah Kerja Puskesmas Palaran Kota Samarinda Tahun 2019. Published online 2014.
  19. Hasina R. Hubungan Tingkat Kepatuhan, Kepuasan Terapi Dengan Kualitas Hidup Pasien Usia Lanjut Diabetes Melitus Tipe 2. 2014;4.
  20. Shakya P, Shrestha A, Karmacharya BM, Morisky DE, Kulseng BE. Factors Associated with Medication Adherence among Patients with Type 2 Diabetes Mellitus: A Hospital-Based Cross-Sectional Study in Nepal. IJERPH. 2023;20(2):1537. doi:10.3390/ijerph20021537
  21. Paraidathathu T, Azuana, Islahudin F, Ahmad. Medication adherence in patients with type 2 diabetes mellitus treated at primary health clinics in Malaysia. PPA. Published online June 2013:525. doi:10.2147/PPA.S44698
  22. Akrom A, Sari OM, Urbayatun S, Saputri Z. Analisis Determinan Faktor-Faktor yang Berhubungan dengan Kepatuhan Minum Obat Pasien Diabetes Tipe 2 di Pelayanan Kesehatan Primer. J Sains Farm Klin. 2019;6(1):54. doi:10.25077/jsfk.6.1.54-62.2019



DOI: https://doi.org/10.22146/jmpf.84431

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