* Corresponding Author
Gambaran Kualitas Hidup pada Pasien Diabetik Retinopati Berdasarkan Tingkat Keparahan Visus
https://doi.org/10.22146/jmpf.44456 Novita Dhewi Ikakusumawati(1*), Dewi Magistasari(2), Novena Adi Yuhara(3), Tri Murti Andayani(4), Supanji Supanji(5), Susi Ari Kristina(6)
(1) Graduate Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada
(2) Graduate Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada
(3) Graduate Program of Pharmacy Management, Faculty of Pharmacy, Universitas Gadjah Mada
(4) Faculty of Pharmacy, Universitas Gadjah Mada
(5) RSUP dr. Sardjito, Yogyakarta
(6) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author
Abstract
Diabetic retinopathy (DR) is one of the microvascular complications of diabetes mellitus (DM) which incidence increases with the high prevalence of DM. The presence of these complications will affect quality of life, especially vision-related. The purpose of this study was to determine the quality of life in RD patients assessed using the VFQ-25 and EQ-5D questionnaires, and to determine the of quality of life based on the visual acuity (VA) severity. This study was an observational study in outpatient with diabetic retinopathy during October 2018 – Januari 2019 period, in RSUP dr. Sardjito and RS Mata Dr. YAP, Yogyakarta. The design of this study was cross sectional which observed quality of life and vision. Quality of life was measured by specific for vision instrument (NEI-VFQ-25) and generic instrument (EQ-5D-5L). The number of patients in this study were 100 patients with an average age of 55 years, the most frequent type of RD was 84% proliferative RD. The average quality of life scores in RD patients measured using the VFQ-25 and EQ-5D utility questionnaires were 64.1 ± 16.2 and 0.61 ± 0.24, respectively. Based on VFQ-25, the most affected subscales were driving, dependence, and role difficulties subscale. Meanwhile, domains that have the most problems with the EQ-5D were pain / discomfort and anxiety / depression (78%). The total VFQ-25 score decreased with increasing visual severity, i.e. normal / mild (n = 19) 73.50 ± 15.08; moderate (n = 15) 68.14 ± 15.33; and severe (n = 66) 60.48 ± 15.64. The EQ-5D utility score showed a similar pattern, with scores of 0.66 ± 0.27 (normal / mild); 0.65 ± 0.22 (medium); and 0.59 ± 0.24 (severe); respectively. The higher severity of visual acuity so the quality of life become lower.
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1. Ogurtsova K, da Rocha Fernandes JD, Huang Y, et al. IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res Clin Pract. 2017;128:40-50.
2. Soewondo P, Ferrario A, Tahapary DL. Challenges in diabetes management in Indonesia: a literature review. Global Health. 2013;9:63.
3. Assosiation AD. Standards of Medical Care in Diabetes. Diabetes Care. 2018;41:S1-159.
4. Kim JH, Kim DJ, Jang HC, Choi SH. Epidemiology of Micro- and Macrovascular Complications of Type 2 Diabetes in Korea. Diabetes Metab J. 2011;35(6):571-577.
5. Infodatin. Situasi dan Analisis Diabetes. January 2014.
6. Association AD. Diabetic Retinopathy. Diabetes Care. 2002;25(suppl 1):s90-s93.
7. Khan S, Wong S, Deane J, Lawrence I. Fundamentals in diabetes. Part 2: Diabetic retinopathy. J Diabetes Nurs. 2011;15:298-307.
8. Alcubierre N, Rubinat E, Traveset A, et al. A prospective cross-sectional study on quality of life and treatment satisfaction in type 2 diabetic patients with retinopathy without other major late diabetic complications. Health Qual Life Outcomes. 2014;12:131.
9. Davidov E, Breitscheidel L, Clouth J, Reips M, Happich M. Diabetic retinopathy and health-related quality of life. Graefes Arch Clin Exp Ophthalmol. 2009;247(2):267-272.
10. Fenwick EK, Pesudovs K, Khadka J, et al. The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project. Qual Life Res. 2012;21(10):1771-1782.
11. Park Y, Shin JA, Yang SW, et al. The Relationship between Visual Impairment and Health-Related Quality of Life in Korean Adults: The Korea National Health and Nutrition Examination Survey (2008–2012). PLoS One. 2015;10(7):e0132779.
12. Pereira DM, Shah A, D’Souza M, et al. Quality of Life in People with Diabetic Retinopathy: Indian Study. J Clin Diagn Res. 2017;11(4):NC01-NC06.
13. Mazhar K, Varma R, Choudhury F, et al. Severity of diabetic retinopathy and health-related quality of life: the Los Angeles Latino Eye Study. Ophthalmology. 2011;118(4):649-655.
14. Herdman M, Gudex C, Lloyd A, et al. Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Qual Life Res An Int J Qual Life Asp Treat Care Rehabil. 2011;20(10):1727-1736.
15. Çetin EN, Bulgu Y, Zencir M, Avunduk AM, Yaylali V, Yildirim C. Vision related quality of life in patients with diabetic retinopathy. Retina-Vitreus. 2012;20:213-217.
16. Mangione CM, Lee PP, Gutierrez PR, et al. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol (Chicago, Ill 1960). 2001;119(7):1050-1058.
17. Ria S. Pengaruh Karakteristik Pasien terhadap Kualitas Hidup dan Outcome Klinik Pasien Diabetes Retinopati di Rsup Dr. Sarjito. 2018.
18. Fajariyanti Y, Wildan A, Johan A. PERBEDAAN QUALITY OF LIFE PADA PENDERITA PROLIFERATIVE DIABETIC RETINOPATHY DENGAN DAN TANPA LASER PANRETINAL PHOTOCOAGULATION. J Kedokt DIPONEGORO. 2017;6(2):1410-1417.
19. Susetyo G. Perbedaan Kualitas Hidup yang Berhubungan dengan Gangguan Penglihatan pada Penderita Non Proliferative Diabetic Retinopathy dan Proliferative Diabetic Retinopathy. March 2013.
20. Rema M, Sujatha P, Pradeepa R. Visual outcomes of pan-retinal photocoagulation in diabetic retinopathy at one-year follow-up and associated risk factors. Indian J Ophthalmol. 2005;53(2):93-99.
21. Shrestha GS, Kaiti R. Visual functions and disability in diabetic retinopathy patients. J Optom. 2014;7(1):37-43.
22. Zhao Y, Singh RP. The role of anti-vascular endothelial growth factor (anti-VEGF) in the management of proliferative diabetic retinopathy. Drugs Context. 2018;7.
23. Kamran JS, Jafroudi S, Leili EKN, Chafjiri AS, Paryad E. Quality of Life in Patients with Diabetic Retinopathy. J Holist Nurs Midwifery. 2017;27(1):69-77.
24. Purba FD, Hunfeld JAM, Iskandarsyah A, et al. The Indonesian EQ-5D-5L Value Set. Pharmacoeconomics. 2017;35(11):1153-1165.
25. Ophtalmologi IC of. Visual Standards : Aspects and Ranges of Visual Loss with Emphasis on Population Survey. In: 29th International Congress of Ophthalmology. ; 2002.
26. Akinci F, Yildirim A, Gözü H, Sargın H, Orbay E, Sargın M. Assessment of health-related quality of life (HRQoL) of patients with type 2 diabetes in Turkey. Diabetes Res Clin Pract. 2008;79(1):117-123.
27. Aklima A, Kritpracha C, Thaniwattananon P. Dietary Behaviors among Patients with Type 2 Diabetes Mellitus in Indonesia. Nurse Media J Nurs. 2013;3(1):499-509.
28. Waspadji S. Diabetes Melitus: Mekanisme Dasar Dan Pengelolaannya Yang Rasional.; 2005.
29. Wild S, Roglic G, Green A, Sicree R, King H. Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047-1053.
30. McLeod S, Feder R, Olsen T, Al E. Diabetic Retinopathy PPP.; 2014.
31. Cheung N, Wang JJ, Klein R, Couper DJ, Sharrett AR, Wong TY. Diabetic Retinopathy and the Risk of Coronary Heart Disease: The Atherosclerosis Risk in Communities Study. Diabetes Care. 2007;30(7):1742-1746.
32. Nurchayati S. Fakultas Ilmu Keperawatan Program Pasca Sarjana Kekhususan Keperawatan Medikal Bedah Universitas Indonesia Depok.; 2010.
33. Gonder JR, Walker VM, Barbeau M, et al. Costs and Quality of Life in Diabetic Macular Edema: Canadian Burden of Diabetic Macular Edema Observational Study (C-REALITY). J Ophthalmol. 2014;2014:939315.
34. Warrian KJ, Lorenzana LL, Lankaranian D, Dugar J, Wizov SS, Spaeth GL. The assessment of disability related to vision performance-based measure in diabetic retinopathy. Am J Ophthalmol. 2010;149(5):852-860.e1.
35. Okamoto F, Okamoto Y, Fukuda S, Hiraoka T, Oshika T. Vision-Related Quality of Life and Visual Function Following Vitrectomy for Proliferative Diabetic Retinopathy. Am J Ophthalmol. 2008;145(6):1031-1036.e1.
36. Yu Y, Feng L, Shao Y, et al. Quality of life and emotional change for middle-aged and elderly patients with diabetic retinopathy. Int J Ophthalmol. 2013;6(1):71-74.
37. Pan C-W, Wang S, Wang P, Xu C-L, Song E. Diabetic retinopathy and health-related quality of life among Chinese with known type 2 diabetes mellitus. Qual Life Res. 2018;27(8):2087-2093.
38. Polack S, Alavi Y, Rachapalle Reddi S, Kulothungan V, Kuper H. Utility values associated with diabetic retinopathy in Chennai, India. Ophthalmic Epidemiol. 2015;22(1):20-27.
DOI: https://doi.org/10.22146/jmpf.44456
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