Asupan zat besi, kadar hepsidin, dan kadar hemoglobin pada mahasiswi obesitas dan normal

https://doi.org/10.22146/ijcn.79076

Fonny Kurnia Putri(1), Desmawati Desmawati(2*), Defrin Defrin(3)

(1) Program Studi Kebidanan Program Magister, Fakultas Kedokteran, Universitas Andalas, Padang / Institut Kesehatan Mitra Bunda, Batam, Indonesia
(2) Departemen Ilmu Gizi Fakultas Kedokteran, Universitas Andalas, Padang, Indonesia
(3) Departemen Obstetri dan Ginekologi Fakultas Kedokteran, Universitas Andalas, Padang, Indonesia
(*) Corresponding Author

Abstract


Fe intake, hepcidin levels, and hemoglobin levels in obese and normal female students

Background: The most common anemia is related to problems with nutritional status. Obesity increases the risk of anemia because of the accumulation of fat in adipose tissue that triggers inflammation which can lead to anemia.

Objective: This study aims to determine differences in iron (Fe) intake, hepcidin levels, and hemoglobin (Hb) levels in obese and normal female students.

Methods: This research is an observational study with a comparative cross-sectional research design. Sampling was done by systematic random sampling. Data assessment of Fe intake, hepcidin levels, and Hb levels was carried out by SQ-FFQ interview, ELISA method, and cyanmethemoglobin method. Normality test and data analysis were performed using the Shapiro-Wilk test, independent t-test, Mann-Whitney, and Chi-Square.

Results: The mean intake of Fe in obesity was 14.39±6.87 mg higher than the normal female students' 14.14±7.50 mg (p=0.726). The median hepcidin level in obesity was 322.32 pg/mL higher than normal female students 315.67 pg/mL (p=0.677). The mean hemoglobin level in obesity was 11,2±1,1 g/dL lower than normal female students 12,1±1,09 g/dL (p=0.001).

Conclusions: There was no significant difference in Fe intake and hepcidin levels in the obese and normal female students. However, there was a significant difference in hemoglobin levels in obese and normal female students.


Keywords


anemia; Fe intake; hemoglobin levels; hepcidin levels; obesity

Full Text:

PDF


References

  1. World Health Organization. World health statistics 2021: monitoring health for the SDGs sustainable development global. [series online] 2021 [cited 2022 Juni]. Available from: URL: https://www.who.int/publications/i/item/9789240027053
  2. Badan Penelitian dan Pengembangan Kesehatan RI. Riset Kesehatan Dasar (Riskesdas) tahun 2018. [series online] 2018 [cited 2022 Juni]. Available from: URL: https://layanandata.kemkes.go.id/katalog-data/riskesdas/ketersediaan-data/riskesdas-2018
  3. Kementrian Kesehatan RI. Profil kesehatan Indonesia 2017. [series online] 2018 [cited 2022 Juni]. Available from: URL: https://www.kemkes.go.id/id/profil-kesehatan-indonesia-2017
  4. Dinas Kesehatan Kota Padang. Profil kesehatan tahun 2019. Padang: Dinas Kesehatan Kota Padang; 2019.
  5. Dieny FF, Rahadiyanti A, Kurniawati DM. Gizi prakonsepsi. Jakarta: Bumi Medika; 2019.
  6. Dieny FF, Widyastuti N, Fitranti DY, Nissa C, Tsani AFA, Jauharany FF. Defisiensi besi pada wanita usia subur pranikah obesitas. Media Gizi Mikro Indonesia. 2019;10(2):101-10. doi: 10.22435/mgmi.v10i2.599
  7. Fasrini UU, Audina W, Defrin, Desmawati, Karmia HR, Abdiana. Hubungan asupan besi heme dan non heme kadar ferritin pada calon pengantin perempuan di Kota Padang. Jurnal Sehat Mandiri. 2021;16(1):115-30. doi: 10.33761/jsm.v16i1.363
  8. Cepeda-Lopez AC, Baye K. Obesity, iron deficiency and anaemia: a complex relationship. Public Health Nutr. 2020;23(10):1703-4. doi: 10.1017/S1368980019004981
  9. Al-Attar Z, Jassim S, Hashim I. Prevalence of anemia types among overweight and obese patients attending the obesity research and therapy unit at AL-Kindy College of Medicine. International Medical Journal. 2020;24(3):435-8.
  10. Sandy YD, Tamtomo DG, Indarto D. Hubungan berat badan dengan kejadian anemia remaja putri di Kabupaten Boyolali. Jurnal Dunia Gizi. 2020;3(2):94-8. doi: 10.33085/jdg.v3i2.4744
  11. Pasalina PE, Jurnalis DE, Ariadi. Hubungan indeks masa tubuh dengan kejadian anemia pada wanita usia subur pra nikah. Jurnal Ilmu Keperawatan dan Kebidanan. 2019;10(1):12–20.
  12. Wirth JP, Woodruff BA, Engle-Stone R, Namaste SM, Temple VJ, Aaron GJ, et al. Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. Am J Clin Nutr. 2017;106(Suppl 1):416S-427S. doi: 10.3945/ajcn.116.143073
  13. Nisa AK, Nisa C, Probosari E. Perbedaan asupan gizi dan kadar hemoglobin pada remaja perempuan obesitas dan tidak obesitas. Journal of Nutriotion College. 2019;8(1):21–8. doi: https://doi.org/10.14710/jnc.v8i1.23809
  14. Kementerian Pendidikan RI. Statistik pendidikan tinggi tahun 2020. Jakarta: Direktorat Jendral Pendidikan Tinggi Kementerian Pendidikan dan Kebudayaan Indonesia; 2020.
  15. Sumarmi S, Puspitasari N, Handajani R, Wirjatmadi B. Underweight as a risk factor for iron depletion and iron-deficient erythropoiesis among young women in rural areas of East Java, Indonesia. Mal J Nutr. 2016;22(2):219-32.
  16. Santrock JW. Life span development: perkembangan masa hidup jilid I. (Alih bahasa: B. Widyasinta). Jakarta: Penerbit Erlangga; 2012.
  17. Fryar CD, Carroll MD, Afful J. Prevalence of overweight, obesity, and severe obesity among adults aged 20 and over: United States, 1960–1962 through 2017–2018. [series online] 2018 [cited 2022 Juni]. Available from: URL: https://www.cdc.gov/nchs/data/hestat/obesity_adult_15_16/obesity_adult_15_16.pdf
  18. Nugroho PS. Jenis kelamin dan umur berisiko terhadap obesitas pada remaja di Indonesia. An-Nadaa: Jurnal Kesehatan Masyarakat. 2020;7(2):110–4. doi: 10.31602/ann.v7i2.3581
  19. Tijerina-Sáenz A, Martínez-Garza NE, Ramírez-López E, Solís-Pérez E, Martínez-Báez AZ. Iron status and dietary intakes of iron in normal-weight and obese young Mexican women. Nutr Hosp. 2015;31(6):2412-8. doi: 10.3305/nh.2015.31.6.8687
  20. Lestari IP, Ronitawati P, Melani V. Perbedaan densitas energi konsumsi dan densitas asupan zat gizi berdasarkan status gizi pada guru di Jakarta Barat. Darussalam Nutrition Journal. 2020;4(2):72–81. doi: 10.21111/dnj.v4i2.3981
  21. Rasyid I, Bahrun U, Kurniawan L. Analisis kadar hepcidin pada obesitas sentral dan non obesitas sentral. Jurnal Sains Keolahragaan dan Kesehatan. 2021;6(1):70–81. doi: 10.5614/jskk.2021.6.1.8
  22. Wisnusanti SU, Lestari LA, Helmyati S. Iron status and hepcidin level of normal and obese adolescents. Jurnal Gizi dan Dietetik Indonesia. 2021;9(2):85–93. doi: 10.21927/ijnd.2021.9(2).85-93
  23. Peraturan Menteri Kesehatan Republik Indonesia Nomor 37 Tahun 2012 tentang Pedoman Penyelenggaraan Penyelenggaraan Laboratorium Pusat Kesehatan.
  24. Elmugabil A, Rayis DA, Abdelmageed RE, Adam I, Gasim GI. High level of hemoglobin, white blood cells and obesity among Sudanese women in early pregnancy: a cross-sectional study. Future Sci OA. 2017;3(2):FSO182. doi: 10.4155/fsoa-2016-0096
  25. Hoffbrand AV, Moss PAH. Kapita selekta hematologi (6th ed.). Jakarta: EGC; 2013.
  26. Natasya VSA, Afirin MZ, Aini I. Analisis kadar hemoglobin pada masa menstruasi (literature review). Jurnal Kebidanan. 2022;12(1):9-15.



DOI: https://doi.org/10.22146/ijcn.79076

Article Metrics

Abstract views : 2430 | views : 3692

Refbacks

  • There are currently no refbacks.




Copyright (c) 2023 Jurnal Gizi Klinik Indonesia

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Jurnal Gizi Klinik Indonesia (JGKI) Indexed by:
 
  

  free
web stats View My Stats