Pemberian minuman secang (Caesalpinia sappan l.) terhadap kadar malondialdehid plasma dan kebugaran jasmani pada pegawai penderita prehipertensi

https://doi.org/10.22146/ijcn.33242

Farida Fitriyanti(1*), Susetyowati Susetyowati(2), Mae Sri Hartati Wahyuningsih(3)

(1) Minat Gizi dan Kesehatan, Program Studi Magister Ilmu Kesehatan Masyarakat, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada
(2) Departemen Gizi dan Kesehatan, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada
(3) Departemen Farmakologi, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada / Pusat Kedokteran Herbal, Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Effect of Secang (Caesalpinia sappan L.) drink toward plasma-malondialdehyde level and physical fitness in prehypertensive government office worker

Background: Prehypertension is associated with a higher risk of hypertension and cardiovascular disease. A government office worker has lower physical activity, thus increasing the risk of hypertension, low physical fitness, and a higher level of oxidative stress. Free radical which is the product of oxidative stress can be reduced by antioxidants. Secang (Caesalpinia sappan L.) is one of the ingredients in a traditional herbal drink (jamu) and a natural source of antioxidants in the form of polyphenol.

Objective: The purpose of this study is to discover the effect of secang drink supplementation, and efficacy towards plasma MDA level and physical fitness on a government office worker.

Methods: This study conducted with true experimental by pre and post-test control group design. The subject is 35 prehypertensive government office workers aged between 25-45 years old in Yogyakarta, divided into treatment and control groups. Secang is given in 3.8g teabag which brewed in 200cc hot water, consumed for 4 weeks. Plasma MDA level is measured using TBARS, and physical fitness is measured using the Harvard step test. Results are analyzed using student paired t-test, Pearson and Spearman correlation test, regression test, and ANOVA.

Results: There’s insignificant decrease of plasma MDA level between intervention group (from 4,28±3,16 to 3,66±1,21) and control group (4,85±2,35 to 3,65±1,33). There’s difference on Harvard step test results, intervention group increase from 35,54±20,18 to 48,09±21,86 in male, while 11,56±4,94 to 13,87±6,25 in female. In control group, male subject increase 29,20±10,06 to 38,18±23,62, but decrease 13,30±7,12 to 13,26±2,92 in female.

Conclusions: 4 weeks drinks of 3.8 g Secang drink brewed in 200ml hot water, shows no evidence of lowering oxidative stress (MDA) in plasma, but it may increase physical fitness.


Keywords


Caesalpinia sappan L.; MDA; physical fitness; prehypertension

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DOI: https://doi.org/10.22146/ijcn.33242

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