Suplementasi ekstrak albumin ikan gabus terhadap status gizi dan imunitas pasien stroke

Vivien Novarina Kasim; Sri Manovita Pateda; Veni Hadju; Nurhaedar Jafar

doi:10.22146/ijcn.21964

Suplementasi ekstrak albumin ikan gabus terhadap status gizi dan imunitas pasien stroke

https://doi.org/10.22146/ijcn.21964

Vivien Novarina Kasim^(1*), Sri Manovita Pateda⁽²⁾, Veni Hadju⁽³⁾, Nurhaedar Jafar⁽⁴⁾

(1) Departeman Keperawatan, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo
(2) Departemen Kesehatan Masyarakat, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo
(3) Departeman Gizi, Fakultas Kesehatan Masyarakat Universitas Hasanuddin
(4) Departeman Gizi, Fakultas Kesehatan Masyarakat Universitas Hasanuddin
(*) Corresponding Author

Abstract

Background: Malnutrition and immunology change in stroke would affect the outcome of the stroke patient. The supplement of the extract of snakehead fish as an alternative is expected could reduce the effect pasca stroke.

Objective: This study aims to assess the effect of snakehead fish supplementation on nutritional status, levels of albumin, TLC and TNF-α in stroke patients.

Method: This type of study is a quasi-experimental, pre-test post-test group design, by providing treatment to the subject of research and treatment effects were measured and analyzed. Subjects were divided into two groups; a first group which receives 3 x 2 capsule of snakehead fish supplementation as well as diet and nutrition education (intervention group) and the second group that received only diet and education (control group).

Results: From the results, it was found that nutritional status, which was obtained by measuring UAC in cases and controls are good (SG ≥ 85%) but no significant differences between them (p=0.914). There are significant differences between albumin levels before and after intervention (p=0.023) with an average increase of 0.2 g/dl, but not in the control group (p=0.931). For TLC values increased in the intervention group (990,5 sel/mm3) and a decrease in the control group (645,03 sel/mm3) with a significant difference in both groups (p=0.034). There was a decrease of TNFα in both group; for cases (mean=-2.91) and controls (mean=-2.58) with significant differences between the two groups (p=0.001).

Conclusion: The supplementation of an extract of snakehead fish could increase the albumin and TLC level and decrease the TNFα in stroke patients.

Keywords

nutritional status; snakehead fish extrac; stroke; TLC; TNFα

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References

Djoenaidi W. Klinis dan penatalaksanaan stroke dan kelainan neurovaskular lain. Pertemuan Ilmiah Nasional I Neuroimaging; 12-15 Mei 2003; Malang, Jawa Timur.
Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol 2007;6(2):182-7.
Sherin A, Khan A, Rehman S, Shah NH, Shabbier G, Zarif M. Comparibility and validity of siriraj stroke score and allen stroke score in differentiation of acute ischemic and haemmorhagic stroke. JPMI 2011;25(3):206-16.
Teasell R, Foley N, Salter K, Bhogal S, Jutay J, Speechley M. Nutritional interventions following stroke. Evidence-based review of stroke rehabilitation (EBRSR) executive summary (13^th edition). [series online] 2010 [2012 Jan]. Available from: URL: http://www.ebrsr.com
Alrasyid H. Immunonutrition, konsep, dan kontroversi (tinjauan pustaka). Majalah Kedokteran Nusantara 2007;40(4):285-90.
Calder PC. Immunonutrition (editorials). BMJ 2003;327(1):117-8.
Cunningham-Rundles S. Nutrition and the immune system of the gut. Nutrition 1998;14(7):573-9.
Arifin H. Peranan glutamin. Majalah Kedokteran Nusantara 2009;42(1):66-71.
Taslim NA, Tawali AB, Hadju V, Attamimi F. Laporan penelitian ikan Gabus. Makassar: Pusat Penelitian Pangan, Gizi dan Kesehatan Universitas Hasanuddin; 2005.
Mulyati S. Pengaruh suplementasi ekstrak ikan gabus pada pasien stroke terhadap skor NHHS [Tesis]. Makassar: Program Studi Ilmu Gizi Fakultas Kedokteran Universitas Hasanuddin; 2010
Musiana, Indri. Pengaruh pemberian kapsul albumin ikan gabus terhadap kadar albumin serum dan luaran penderita stroke iskemik akut [Tesis]. Makassar: Bagian Ilmu Penyakit Saraf Fakultas Kedokteran Universitas Hasanuddin; 2009.
Taslim, N.A. dkk, 2011 adalah Nurpuji Astuti Taslim, Abu Bakar Tawali, Faisal Attamimi, Veni Hadju.Produk Konsntrat Protein Ikan Gabus sebagai supplemen Makanan sumber albumin.(Protein-Concentrate Product from Snake Fish and the Use as Albumin-Source Food Supplement).ID P0027593 B. 16 Februari 2011;
Hartono A. Asuhan nutrisi rumah sakit. Jakarta: EGC; 2000.
FOOD Trial Collaboration. Poor nutritional status on admission predicts poor outcomes after stroke. Stroke 2003;34:1450-6.
Gabriballa SE, Parker SG, Taub N, Castleden CM. Influence on nutritional status on clinical outcome after acute stroke. Am J Clin Nutr 1998;68(2):275-81.
Davalos A, Ricart W, Gonzalez-Huix F, Soler S, Marrugat J, Genís D. Effec of malnutrition after acute stroke on clinical outcome. Stroke 1996;27(6):1028-32.
Evoy D, Lieberman MD, Fahey TJ 3rd, Daly JM. Immunonutrition: the role of arginine. Nutrition 1998;14(7-8):611-7.
Aliah A. Analisis dinamika kadar dan rasio sitokin IL-10/TNF-ά dalam serum dan likuor serebrospinal, serta variasi genetik pada penderita strok iskemik akut [Disertasi]. Makassar: Fakultas Kedokteran Universitas Hasanuddin; 2005.
Islam AA. Rasio TNF-α/IL-10 serum awal sebagai prediktor luaran pada operasi epidural hematom [Disertasi]. Makassar: Fakultas Kedokteran Universitas Hasanuddin; 2007.