Pengaruh diet rendah protein modifikasi terhadap keseimbangan nitrogen pada pasien penyakit ginjal kronik predialisis di RSU Dr. Soeradji Tirtonegoro

Agus Sunaryo; Ahmad Husein Asdie; Susetyowati Susetyowati

doi:10.22146/ijcn.17560

Pengaruh diet rendah protein modifikasi terhadap keseimbangan nitrogen pada pasien penyakit ginjal kronik predialisis di RSU Dr. Soeradji Tirtonegoro

https://doi.org/10.22146/ijcn.17560

Agus Sunaryo^(1*), Ahmad Husein Asdie⁽²⁾, Susetyowati Susetyowati⁽³⁾

(1) Dinas Kesehatan Daerah Militer Iskandar Muda, Banda Aceh
(2) Bagian Penyakit Dalam RSUP Dr. Sardjito Yogyakarta/Fakultas Kedokteran Universitas Gadjah Mada
(3) Program Studi Ilmu Gizi Kesehatan Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author

Abstract

Background: Chronic kidney disease (CKD) is a decreasing function of kidney chronically, progressive, and irreversible. In this condition, one of the symptom found is uremia where gastrointestinal disturbance such as vomiting and anorexia occurred. This causes less nutrition intake, therefore careful diet is needed in attention. One of important aspect of diet procedures for CKD patients is eating management.

Objective: To find out the influence of the modification of low protein diet intake towards nitrogen balance in predialysed CKD patients.

Method: This was an experimental research using randomized controlled trial design.The subjects were predialysed CKD patients treated who fulfilled the following criteria: adult patients, obtained a low protein diet therapy, treated for at least two days, and willing to be examined. The treatments were a modification of low protein diet compare with a hospital standard of low protein diet.The twenty patients were devided into two groups namely a-ten-people treatment group and a-ten-people control.

Result: The statistical test showed that there were no significant difference (p>0.05) in energy and protein intake, urea nitrogen appearance, and nitrogen balance between modification of low protein diet and the hospital standard of low protein diet in predialysed CKD patients.

Conclusion: There were no significant difference in nitrogen balance between modification of low protein diet and the hospital standard of low protein diet in predialysed CKD patients.

Keywords

complementary breastfeeding; infant growth; infant feeding

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References

Roesli R. Gangguan Metabolisme dan Dasar Pengelolaan Nutrisi pada Penyakit Ginjal Kronik. Dalam: Asosiasi Dietesien Indonesia, editor. Prosiding Pertemuan Ilmiah Nasional Dietetik II; 18–19 Februari 2005; Bandung, Indonesia; 2005. h. 181–90.

Kresnawan T. Penatalaksanaan Diet pada Penyakit Ginjal Kronik. Dalam: Asosiasi Dietesien Indonesia, editor. Prosiding Pertemuan Ilmiah Nasional Dietetik II; 18–19 Februari 2005; Bandung, Indonesia; 2005. h.192–9.

Wells C. Optimizing Nutrition in Patients with Chronic Kidney Disease. Nephrol Nurs J 2003;30(6):637–42.

Lestiani L. Terapi Nutrisi pada Insufisiensi Ginjal:Penatalaksanaan Nutrisi Secara Paripurna pada Berbagai Penyakit Ditinjau dari Aspek Kedokteran Molekuler dan Aplikasi Klinis Praktis. Dalam: Perhimpunan Dokter Gizi Medik Indonesia, editor. Kongres Nasional III Perhimpunan Dokter Gizi Medik Indonesia; 11–13 Februari 2004; Bandung, Indonesia; 2004. h. 62-4.

Gibson RS. Principles of Nutritional Assessment. New York: Oxford University Press; 1990. p. 326–32.

Crim CM, Munro HN. Proteins and Amino Acid. In: Shils ME, Olson JA, et al., editors. Modern Nutrition in Health and Disease. Philadelphia: Lea and Febriger; 1994. p. 3–31.

Moehyi S. Pengaturan Makanan dan Diet untuk Penyembuhan Penyakit. Jakarta: PT Gramedia; 1999.

Maroni BJ, Staffeld C, Young VR, Manatunga A, Tom K. Mechanism Permitting Nephrotic Patients to Achieve Nitrogen Equillibrium with a Protein-Restricted Diet. J Clin Invest 1997;99(10):2479–87.

Sacher RA, McPherson RA. Tinjauan Klinis Hasil Pemeriksaan Laboratorium. (Terjemahan) Pendit BU, Wulandari H. Jakarta: Buku Kedokteran EGC; 2002. h. 291–5.

Tumbelaka AR, Riono P, Sastroasmaro S, Wirjodiardjo M, Pudjiastuti P. Pemilihan Uji Hipotesis. Dalam: Sastroasmoro S, Ismael S, editor. Dasar-Dasar Metodologi Penelitian Klinis.

Jakarta: Binarupa Aksara; 2002. h. 250-1.

Brenner BM, Lazarus M. Chronik Renal Failure. In: Isselbacher KJ, Braunwald E, Wilson DJ, Martin JB, editors. Harrison’s Principles of Internal Medicine. New York: McGraw–Hill Inc; 1994. p.1274–81.

Kanazawa Y, Nakao T, Ohya Y, Shimomitsu T. Association of Socio-Psychological Factors with The Effects of Low Protein Diet for the Prevention of the Progression of Chronic Renal Failure. Intern Med 2005;45(12):199–206.

Lim VS, Flanigan MJ. Protein Intake in Patients with Renal Failure: Comments on the Current NKF- DOQI Guidelines for Nutrition in Chronic Renal Failure. Semin Dial 2001;14(3):150–2.

Akner G, Cederholm. Treatment of Protein Energy Malnutrition in Chronic Nonmalignant Disorders 2001. Am J Clin Nutr;74(1):6–24.

Avesani MC, Draibe SA, Kamimura MA. Decreased Resting Energy Expenditure in Non Dialysed Chronic Kidney Disease Patients. Nephrol Dial Transplant 2004;19(12):3091–7.

Sja’bani M, Widiana IGR, Suhardi. Diet Protein Rendah Jangka Panjang pada Gagal Ginjal Kronik Manfaat dan Resikonya. Jurnal Kedokteran dan Farmasi 1998;9(24):600–4.

Druml W. Nutritional Support in Acute Renal Failure. In: Mitch WE, Klahr S, editors. Handbook of Nutrition and Kidney. 3rd ed. New York: Lippincot Raven; 1998. p. 227-9.

Kopple JD. Nutritional Management of Non Dialysed Patients with Chronic Renal Failure. In: Kopple DJ, Massry SG, editors. Nutritional Management of Renal Disease. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2004. p.379-92.

Tzamaloukas AH, Murata GH, Servila KS, Glew RH. Normalization of Protein Nitrogen Appearance by Various Size Indicators in Patients on Continuous Peritoneal Dialysis. Adv Perit Dial 2003;19:207–11.

Bernhard J, Beaufrere B, Laville M, Fouque D. Adaptive Response to Low Protein Diet in Predialysis Chronic Renal Failure Patients. J Am Soc Nephrol 2001;12:1249-54.

DOI: https://doi.org/10.22146/ijcn.17560