Suplementasi multi mikronutrien dibandingkan Fe-asam folat terhadap kadar hemoglobin dan berat badan ibu hamil anemia
Herta Masthalina(1*), Mohammad Hakimi(2), Siti Helmyati(3)
(1) Jurusan Gizi Poltekkes Kemenkes Mataram
(2) Bagian Obstetri dan Ginekologi, Fakultas Kedokteran Universtas Gadjah Mada
(3) Program Studi Gizi Kesehatan, Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author
Abstract
Background: As a part of global strategy to prevent micronutrient deficiency in pregnant mothers, UNICEF recommends the use of multi-micronutrients supplements as an initial program in developing countries. Therefore, it is necessary to investigate the effect of multi-micronutrient supplementation on Hb level and weight gain of anemic pregnant women in Lombok Tengah District.
Objective: To investigate the effect of multi-micronutrient compared to Fe – folic acid supplementation on Hb level and weight gain of anemic pregnant mothers.
Method: This was a quasi-experimental study with non equivalent control group design. Subjects in the intervention group were given multi-micronutrient supplements provided by UNICEF, whereas subjects in the control group were given Fe – folic acid supplements. The supplements were given daily to the two groups for 91 days. Hb level and weight were measured before and after intervention.
Results: Statistical analysis showed no significant differences (p=0.96) in Hb level and weight gain (p=0.454) between the two groups. The increase of Hb level and weight in the intervention group vs control group were 0,53±0,95 g/dL vs 0,89±1,15 g/dL and 4,89±2,71 kg vs 4,32±1,75 kg, respectively.
Conclusion: There were no significant differences in Hb level and weight gain between pregnant mothers consuming multi-micronutrient supplements compared to those consuming Fe – folic acid supplements.
Keywords
Full Text:
PDFReferences
Paath EF, Rumadasih Y, Heryati. Gizi dalam kesehatan reproduksi. Jakarta: Penerbit Buku Kedokteran EGC; 2005.
Lubis Z. Gizi ibu hamil, makalah pengantar falsafah sains program pascasarjana. Bogor: Institut Pertanian Bogor; 2003.
De Maeyer EM. Pencegahan dan pengawasan anemia defisiensi besi. Ronardy, editor. Jakarta: Widya Medika; 1995.
Vijayaraghavan K. Anemia karena defisiensi zat besi. Dalam: Gibney MJ, Margetts BM, Kearney JM, Arab L, editor. Gizi kesehatan masyarakat. Jakarta: EGC; 2009.
Zagre NM, Desplats G, Adou P, Mamadoultaibou A, Aguayo VM. Prenatal multiple micronutrient supplementation has greater impact on birthweight than supplementation with iron and folic acid – a cluster randomized, double blind, controlled programmatic study in rural Niger. Food Nutr Bull 2007;28(3):317–27.
Gupta P, Ray M, Dua T, Radhakrisman G, Kumar R, Sachdev. Multimicronutrient supplementation for undernourished pregnant women and birth size of their offspring – a double blid, randomized, placebo – controlled trial. Arch Pediatr Adolesc Med [serial online] 2007 Jan [cited 2009 Jun 1];161(1):58-64. Available from: URL: http.//www.archpediatrics.com
Vaidya A, Savilla N, Shrestha BM, Costello AM, Manandhar D, Oarin D. Effect of antenatal multiple micronutrient supplementation on children’s weight and size at 2 years of age in Nepal: follow-up of a double blind randomised controlled trial. Lancet 2008;371(9611):492-9.
Zeng L, Cheng Y, Dang S, Yan H, Dibley MJ, Chang S, Kong L. Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China – double blind cluster randomised controlled trial. BMJ 2008;337:1-11.
Lemeshow S, Hosmer Jr DW, Klar J, Lwanga SK. Besar sampel dalam penelitian kesehatan. Pramono D. 1997 (Alih bahasa). Yogyakarta: UGM Press; 1997.
Almatsier S. Prinsip dasar ilmu gizi. Jakarta: PT. Gramedia Pustaka Utama; 2001.
Institute of Medicine. Nutrition during pregnancy, weight gain and nutrient supplement. Washington: National Academi Press; 1990.
Husaini MA. Study nutritional anemia an assesment of information compilation for supporting and formulating national policy and program. Jakarta: Direktorat Bina Gizi Masyarakat Depkes dan Pusat Penelitian dan Pengembangan Gizi Depkes; 1989.
Gillespie S. Major Issues in the control of iron deficiency, the micronutrient initiative. Canada: UNICEF; 1998.
Winichagoon P. Prevention and control of anemia: Thailand experiences. J Nutr 2002;132(4):862S-6S.
Ulinuha. Pengaruh pemberian vitamin C terhadap peningkatan kadar hemoglobin ibu hamil yang mendapat suplementasi kapsul besi. Yogyakarta: Fakultas Kedokteran Universitas Gadjah Mada; 2003.
Umniyati. Pengaruh suplemen multi gizi mikro terhadap penambahan berat badan hamil: sebuah studi prospektif di Lombok. [serial online] 2007 [cited 2009 March 20]. Available from: URL: http.//www.klikdokter.com
Price SA, Mc Carthy LW. Patofisiologi proses-proses penyakit. Jakarta: EGC; 1994.
Allen LH, Peerson JM. Maternal micronutrient suplementation study group (MMSG). Impact of multi micronutrient versus iron-folic acid supplements on maternal anemia and micronutrient status in pregnancy. Food Nutr Bull 2009;3(4):S527-32.
DOI: https://doi.org/10.22146/ijcn.15375
Article Metrics
Abstract views : 4694 | views : 7861Refbacks
- There are currently no refbacks.
Copyright (c) 2016 Jurnal Gizi Klinik Indonesia (The Indonesian Journal of Clinical Nutrition)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.