Angiotensin Converting Enzyme (ACE) Inhibitory Activity of Peptide Fraction of Germinated Pigeon Pea (Cajanus cajan (L.) Millsp.)
Ketut Ratnayani(1*), I Ketut Suter(2), Nyoman Semadi Antara(3), I Nengah Kencana Putra(4)
(1) Department of Chemistry, Faculty of Natural Sciences, Udayana University, Denpasar 80361, Indonesia
(2) Department of Food Science and Technology, Faculty of Agricultural Technology, Udayana University, Denpasar 80361, Indonesia
(3) Department of Agroindustrial Technology, Faculty of Agricultural Technology, Udayana University, Denpasar 80361, Indonesia
(4) Department of Food Science and Technology, Faculty of Agricultural Technology, Udayana University, Denpasar 80361, Indonesia
(*) Corresponding Author
Abstract
Keywords
Full Text:
Full Text PDFReferences
[1] de Castro, R.J.S., and Sato, H.H., 2015, Biologically active peptides: Processes for their generation, purification and identification, and applications as natural additives in the food and pharmaceutical industries, Food Res. Int., 74, 185–198.
[2] Malaguti, M., Dinelli, G., Leoncini, E., Bregola, V., Bosi, S., Cicero, A.F.G., and Hrelia, S., 2014, Bioactive peptides in cereals and legumes: Agronomical, biochemical and clinical aspects, Int. J. Mol. Sci., 15, 21120–21135.
[3] Sangronis, E., and Machado, C.J., 2007, Influence of germination on the nutritional quality of Phaseolus vulgaris and Cajanus cajan, LWT Food Sci. Technol., 40 (1), 116–120.
[4] Sefatie, R.S., Fatoumata, T., Eric, K., Shi, Y.H., and Le, G., 2013, In vitro antioxidant activities of protein hydrolysate from germinated black soybean (Glycine max L.), Adv. J. Food Sci. Technol., 5(4), 453–459.
[5] Singh, U., and Jambunathan, R., 1982, Distribution of seed protein fractions and amino acids in different anatomical parts of chickpea (Cicer arietinum L.) and pigeon pea (Cajanus cajan L.), Plant Foods Hum. Nutr., 31 (4), 347–354.
[6] Mandal, P., Misra, T.K., Sarkar, A., Ghosh, A., and Sircar, P.K., 2008, Dynamic peptide profiles of germinating mungbean: In relation to their nature and separation pattern, Indian J. Plant Physiol., 13 (2), 111–117.
[7] Bamdad, F., Dokhani, S., Keramat, J., and Zareie, R., 2009, The impact of germination and in vitro digestion on the formation of Angiotensin Converting Enzyme (ACE) inhibitory peptides from lentil proteins compared to whey proteins, Int. J. Nutr. Food Eng., 3 (1), 109–119.
[8] Layne, E., 1957, Spectrophotometric and turbidimetric methods for measuring proteins, Methods Enzymol., 3, 447–455.
[9] Cushman, D.W., and Cheung, H.S., 1971, Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung, Biochem. Pharmacol., 20 (7), 1637–1648.
[10] Siow, H.L., and Gan, C.Y., 2013, Extraction of antioxidative and antihypertensive bioactive peptide from Parkia speciosa seeds, Food Chem., 141 (4), 3435–3442.
[11] Waters, 1993, ACCQ-Fluor Reagent Kit, http://www.waters.com/webassets/cms/support/docs/wat0052881.pdf.
[12] Waters, 2005, Masslynx 4.1. Getting Starting Guide, Waters Corporation, USA.
[13] Xiao, J.F., Zhou, B., and Ressom, H.W., 2012, Metabolite identification and quantitation in LC-MS/MS-based metabolomics, Trends Anal. Chem., 32, 1–14.
[14] Sangronis, E., Rodriguez, M., Cava, R., and Torres, A., 2006, Protein quality of germinating Phaseolus vulgaris, Eur. Food Res. Technol., 222 (1-2), 144-148.
[15] Chinq-Mars, C.D., 2006, Angiotensin converting enzyme inhibitory peptide from the hydrolysis of Pacific Hake fillet by commercial protease, Thesis, British Columbia University.
[16] Ryan, J.T., Ross, R.P., Bolton, D., Fitzgerald, G.F., Stanton, C., 2011, Bioactive peptide from muscle sources: Meat and fish, Nutrients, 3 (9), 765–791.
[17] Natesh, R., Schwager, S.I.U., Sturrock, E.D., and Achraya, K.R., 2003, Crystal structure of the human angiotensin-converting enzyme-lisinopril complex, Nature, 421 (6922), 551–554.
[18] Cheung, H.S., Wang, F.L., Ondetti, M.A., Sabo, E.F., and Cushman, D.W., 1980, Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence, J. Biol. Chem., 255 (2), 401-407.
DOI: https://doi.org/10.22146/ijc.37513
Article Metrics
Abstract views : 2909 | views : 2452Copyright (c) 2019 Indonesian Journal of Chemistry
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Indonesian Journal of Chemistry (ISSN 1411-9420 /e-ISSN 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.
View The Statistics of Indones. J. Chem.