A Novel Spectrophotometric Method for Determination of Histamine Based on Its Complex Reaction with Ni(II) and Alizarin Red S

https://doi.org/10.22146/ijc.23621

Miftakhul Jannatin(1), Ganden Supriyanto(2*), Pratiwi Pudjiastuti(3)

(1) Department of Chemistry, Faculty of Science and Technology, Airlangga University, Jl. Mulyorejo Kampus C UNAIR Surabaya 60115
(2) Department of Chemistry, Faculty of Science and Technology, Airlangga University, Jl. Mulyorejo Kampus C UNAIR Surabaya 60115 Laboratory of Sensor and Biosensor, Institute of Tropical Disease, Airlangga University, Jl. Mulyorejo Kampus C UNAIR Surabaya 60115
(3) Department of Chemistry, Faculty of Science and Technology, Airlangga University, Jl. Mulyorejo Kampus C UNAIR Surabaya 60115
(*) Corresponding Author

Abstract


The development of analytical methods of histamine using Ni (II) and alizarin red S reagents by UV-Vis spectrophotometry has been done. The objective of this research is to determine the ability of Ni(II) and alizarin red S to form color complex compound with histamine and it will be used to detect the presence of histamine qualitatively and quantitatively as well. Absorbance was measured at a maximum wavelength of 604 nm. In this method, it has been carried out optimization of analytical parameters such as the concentration of Ni(II), the concentration of alizarin red S, pH, and respond time. Analytical parameter optimization showed concentration of Ni(II) is 20 ppm, alizarin red S 75 ppm, pH 8, and a respond time of 15 minutes. Method validation indicated that the coefficient of variation, detection limit, and the limit of quantitation are 0.245%; 9.49 ppm; and 31.62 ppm respectively with a sensitivity of 0.0063/ppm and linearity of 0.99. Accuracy to histamine with a concentration of 50, 75, and 125 ppm are 105.87%, 101.06%, 97.21%, respectively.

Keywords


histamine; Ni(II); alizarin red S; spectrophotometry

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References

[1] Chimalakonda, K.C., Pang, E., Weaver, J.L., Howard, K.E., Patel, V., and Boyne, M.T.II., 2015, Development and validation of a liquid-chromatography tandem mass spectrometry method to determine in vitro and in vivo histamine release, J. Pharm. Biomed. Anal., 102, 494–499.

[2] Tjay, T.H., and Rahardja, K., 2007, Obat-obat penting khasiat, penggunaan, dan efek-efek sampingnya, 6th ed., Elex Media Komputindo, Jakarta – Indonesia, 193.

[3] Evangelista, W.P., Silva, T.M., Guidi, L.R., Tette, P.A.S., Byrro, R.M.D., Silva, P.S., Fernandes, C., and Gloria, M.B.A., 2016, Quality assurance of histamine analysis in fresh and canned fish, Food Chem., 211, 100–106.

[4] Haas, H.L., Sergeeva, O.A., and Selbach, O., 2008, Histamine in the nervous system, Physiol. Rev., 88 (3), 1183–1241.

[5] Golan, T.A., Armstong, E.J., and Armstong, A.J., 2011, Principles of Pharmacology, 3rd ed., Lippincott Williams & Wilkins.

[6] Ayesh, A.M., Ibraheim, M.N., El-Hakim, A.E., and Mostafa, E.A.H., 2012, Exploring the contamination level by biogenic amines in fish samples collected from markets in Thuel – Saudi Arabia, Afr. J. Microbiol. Res., 6 (6), 1158–1164.

[7] Fernandez, M., Linares, D.M., del Rio, B., Ladero, V., and Alvarez, M.A., 2007, HPLC quantification of biogenic amines in cheeses: Correlation with PCR-detection of tyramine-producing microorganisms, J. Dairy Res., 74 (3), 276–282.

[8] Akbari-adergani, B., Norouzi, P., Ganjali, M.R., and Dinarvand, R., 2010, Ultrasensitive flow-injection electrochemical method for determination of histamine in tuna fish sample, Food Res. Int., 43 (4), 1116–1122.

[9] Degefu, H., Amare, M., Tessema, M., and Admassie, S., 2014, Lignin modified glassy carbon electrode for the electrochemical determination of histamine in human urine and wine samples, Electrochim. Acta, 121, 307–314.

[10] Tao, Z., Sato, M., Han, Y., Tan, Z., Yamaguchi, T., and Nakano, T., 2011, A simply and rapid method for histamine analysis in fish and fishery products by TLC determination, Food Control, 22 (8), 1154–1577.

[11] Wang, Z., Wu, J., Wu, S., and Bao, A., 2013, High performance liquid chromatographic determination of histamine in biological samples: The cerebrospinal fluid challenge – A review, Anal. Chim. Acta, 724, 1–10.

[12] Henry, B., Gizzi, P., and Delpuech, J.J., 2015, Magnetic non-equivalence and dynamic NMR of N-methylene protons in a Histamine-containing pseudopeptide: Alanyl-Glycyl-Histamine, Tetrahedron, 71 (36), 6227–6244.

[13] An, D., Chen, Z., Zheng, J., Chen, S., Wang, L., and Su, W., 2016, Polyoxomatelate functionalized tris(2,2-bipyridyl)dichlororuthenium(II) as the probe for electrochemiluminescence sensing of histamine, Food Chem., 194, 966–971.

[14] Diaz, M., Ladero, V., Redruello, B., Sanchez, E., Rio, B., Fernandez, M., Martin, M.C., and Alvarez, M.A., 2016, A PCR-DGGE method for the identification of histamine-producing bacteria in cheese, Food Control, 63, 216–223.

[15] Tyagi, S., Singh, S.M., Gencaslan, S., Sheldrick, W.S., and Singh, U.P., 2002, Metal-5-fluorouracil-histamine complexes: solution, structural, and antitumour studies, Met.-Based Drugs, 8, 337–345.

[16] Fain, V.Y., Zaitsev, B.E., and Ryabov, M.A., 2004, Metal complexes with alizarin and alizarin red S: Electronic absorption spectra and structure of ligands, Russ. J. Coord. Chem., 30 (5), 365–370.

[17] Day, R.A., and Underwood, A.L., 2002, Analisis Kimia Kuantitatif, 6th ed., Penerbit Erlangga, Jakarta.

[18] Gahlan, A.A., El-Mottaleb, M.A., Badawy, N.A., Kamale, F.H., and Ali, Sh.H., 2014, Spectrophotometeric studies on binary and ternary complexes of some metal ions with alizarin red S and cysteine, Int. J. Adv. Res., 2 (10), 570–584.



DOI: https://doi.org/10.22146/ijc.23621

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