IDENTIFICATION OF THE ISOLATED COMPOUNDS FROM Zingiber amaricans BL. RHIZOME
Sugeng Riyanto(1*)
(1) Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia 55281
(*) Corresponding Author
Abstract
Five extracts were obtained from extraction of rhizomes of Zingiber amaricans. Hexane, dichloromethane and methanol extracts were obtained by maceration, while dichloromethane and acetone extracts the resulted of soxhlet extraction. By column chromatography technique 2,6,9-humulantrien-9-one (zerumbone) was isolated as the major constituent of the hexane, dichloromethane and methanol extracts. The minor constituents were phytosterol mixtures isolated from hexane and dichloromethane extracts. The mixtures consisted cholesterol, campesterol, stigmasterol and b-sitosterol. The structure elucidations of zerumbone was confirmed by spectroscopic method, whereas the phytosterol mixtures was identified by gas chromatography-mass.
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[1] Heyne,K. 1987, Tumbuhan Berguna Indonesia, Jilid I, Badan Litbang Kehutanan, Jakarta.
[2] Matthes, H.W.D., Luu, B. and Ourisson, G., 1980, Phytochem., 19, 2643-2650.
[3] Asmawi, M.Z., Sadikun, A., Jiu, L.L., and Rahman, A.A. 1987, The Bronchodilator and Antiinflamatory effects of Zingiber zerumbet (Lo.) Sm Rhizome, eds. Mohd. Shohimi Mustapha, Proceeding, of Seventh Annual Scientific Meeting of Maspet, 12-13 June 1987
[4] Asmawi, M.Z. and Pauzi, M.A. 1989. Antifertility effect of Lempuyang Gajah (Zingiber zerumbet Lo.), Eight Scientific Meeting of the Malaysian Society of Pharmacology and Physiology 21-22th July 1989,p 26. Kualalumpur.
[5] Masuda, T., Jitoe, A., Kato, S. and Nakatani, N. 1991, Phytochem. 30(7), 2391-2392.
[6] Murakami, A., Takahashi, M., Jiwajinda, S., Koshimizu, K., and Ohigashi, H. 1999, Biosci. Biotechnol. Biochem, 63 (10), 1811-1812.
DOI: https://doi.org/10.22146/ijc.21720
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