The Isolation of Xanthones from Trunk Latex of Garcinia mangostana Linn. and Their Antimicrobial Activities

https://doi.org/10.22146/ijc.21213

Vivi Anggia(1), Amri Bakhtiar(2), Dayar Arbain(3*)

(1) Faculty of Pharmacy/Sumatran Biota Laboratory, Andalas University, Kampus Limau Manis, Padang, 25163, West Sumatera
(2) Faculty of Pharmacy/Sumatran Biota Laboratory, Andalas University, Kampus Limau Manis, Padang, 25163, West Sumatera
(3) Faculty of Pharmacy/Sumatran Biota Laboratory, Andalas University, Kampus Limau Manis, Padang, 25163, West Sumatera
(*) Corresponding Author

Abstract


ɑ-Mangostin (1), β-mangostin (2) and gartanin (3) have been isolated from the trunk latex of Garcinia mangostana Linn. and investigated for their antimicrobial activities against Bacillus subtilis, Enterococcus faecalis, Micrococcus luteus, Salmonella typhosa, Staphylococcus epidermidis, Streptococcus mutans and Vibrio cholerae. The significant antibacterial activity showed by α-mangostin (1) against Bacillus subtilis, Enterococcus faecalis. Staphylococcus epidermidis and Vibrio cholerae, but all compounds showed no activity to inhibit the growth of Micrococcus luteus and Streptococcus mutans.

Keywords


Garcinia mangostana Linn.; trunk latex; ɑ-mangostin; β-mangostin; gartanin

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DOI: https://doi.org/10.22146/ijc.21213

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