Usia menarche sebagai faktor risiko kejadian preeklamsia dan eklamsia

https://doi.org/10.22146/bkm.26341

Astrid Kizy Primadani(1*), Elisabeth S Herini(2), Djaswadi Dasuki(3)

(1) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi Fakultas Kedokteran Universitas Gadjah Mada
(2) Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada
(3) Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Age of menarche as a risk factor for preeclampsia and eclampsia

Purpose

The purpose of this study is to determine the effect of menarche age on the incidence of preeclampsia and eclampsia.

Method

The observational study with the case-control design was conducted involving 90 pregnant and postpartum women. The bivariable analysis used T-test and McNemar test, while multivariable analysis using conditional logistic regression.

Results 

The average age of menarche in the preeclampsia group was one year younger than the non-preeclampsia group. Any increase in one year of age of menarche lowers the risk of preeclampsia and eclampsia by 78%. Risk factors for preeclampsia are increased in pregnant women at age> 35 years and have body mass index before pregnancy> 25 kg/m2.

Conclusion

There is a significant relationship between age of menarche and the incidence of preeclampsia and eclampsia. Body mass index before pregnancy is a confounding factor of the association between age of menarche and the incidence of preeclampsia and eclampsia.


Keywords


preeclampsia; eclampsia; age of menarche; case-control; body mass index



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DOI: https://doi.org/10.22146/bkm.26341

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