Ketahanan hidup 5 tahun pada pasien kanker payudara

Evi Susanti Sinaga; Riris Andono Ahmad; Susanna Hilda Hutajulu

doi:10.22146/bkm.10543

Ketahanan hidup 5 tahun pada pasien kanker payudara

https://doi.org/10.22146/bkm.10543

Evi Susanti Sinaga^(1*), Riris Andono Ahmad⁽²⁾, Susanna Hilda Hutajulu⁽³⁾

(1) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi Fakultas Kedokteran Universitas Gadjah Mada
(2) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi Fakultas Kedokteran Universitas Gadjah Mada
(3) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author

Abstract

Analysis of 5-year survival of patients treated for breast cancer at Sardjito Hospital in Yogyakarta province, Indonesia

Purpose

This study aimed to assess the length of life of breast cancer patients as well as factors related to the prognosis of survival of patients.

Methods

This research was a retrospective study. Samples in this study were patients with breast cancer who were first diagnosed with breast cancer from January 1, 2009 until December 31, 2009 at the Dr. Sardjito Hospital, Yogyakarta. The Kaplan Meier method was used for the data analysis, and final factors were reviewed and those that showed significant association were entered in a Cox regression model. Calculations were performed in Stata 12.0.

Results

Results showed the 5 year survival rate was 51.07%. In bivariate analysis, there was a correlation between the age of diagnosis, education, clinical stage, tumor size and tumor location on 5-year survival in patients with breast cancer. For multivariate analysis, age of diagnosis had the most powerful correlation (HR = 3.73; 95% CI = 1.0 to 13.6) on survival (p = 0.046).

Conclusion

Survival rates of women with breast cancer aged less than 50 years were lower. Young women with breast cancer tended to have more aggressive breast cancer growth and recurrence risks were greater. Efforts are needed for early detection of breast cancer to improve survival in breast cancer patients.

Keywords

breast cancer; survival analysis; Dr. Sardjito hospital; Yogyakarta

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References

Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. Cancer Incedence and Mortality Worldwide: IARC CancerBase No.11 [Internet]. GLOBOCAN 2012. Lyin, France; 2012. Available from: http://globocan.iarc.fr.
International Agency for Research on Cancer. Latest world cancer statistics Global cancer burden rises to 14 . 1 million new cases in 2012 : Marked increase in breast cancers must be addressed Latest world cancer statistics Global cancer burden rises to 14 . 1 million new cases in 2012 : Marked incr. Lyon/Geneva; 2012 p. 1–3.
Wahyuni AS. Analisis Ketahanan Hidup 5 Tahun Pada Penderita Kanker Payudara di Rumah Sakit Kanker Dharmais. Universitas Indonesia; 2002.
Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. RISKESDAS 2013. Jakarta; 2013 p. 86–7.
HOM-Tulip Cancer Registry. Cancer Registry Sardjito. Yogyakarta: Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine Gadjah Mada University/ Dr Sardjito Academic Hospital, Yogyakarta; 2015.
Depkes RI. Pedoman Teknis Pengendalian Kanker Payudara & Kanker Leher Rahim. Jakarta: Departemen Kesehatan RI; 2010.
Bewick V, Cheek L, Ball J. Statistics review 12: survival analysis. Crit Care [Internet]. 2004 Oct [cited 2014 Dec 1];8(5):389–94. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1065034&tool=pmcentrez&rendertype=abstract
National Cancer Institute. SEER Stat Fact Sheets: Female Breast Cancer. Surveillance, Epidemiol End Results Progr [Internet]. 2012; Available from: http://seer.cancer.gov/statfacts/html/breast.html
Brandt J, Garne JP, Tengrup I, Manjer J. Age at Diagnosis in Relation to Survival Following Breast Cancer: A Cohort Study. World J Surg Oncol [Internet]. 2015;13:33. Available from: http://www.wjso.com/content/13/1/33
Notoadmodjo S. Metodologi Penelitian Kesehatan. Jakarta: Rineka Cipta; 2012.
Karimi A, Delpisheh A, Sayehmiri K, Saboori H, Rahimi E. Predictive Factors of Survival Time of Breast Cancer in Kurdistan Province of Iran between 2006-2014: A Cox Regression Approach. Asian Pacific J Cancer Prev [Internet]. 2014 Oct 23;15(19):8483–8. Available from: http://koreascience.or.kr/journal/view.jsp?kj=POCPA9&py=2014&vnc=v15n19&sp=8483.
Canadian Cancer Society. Prognosis and Survival for Breast Cancer. 2016; Available from: http://www.cancer.ca/en/cancer-information/cancer-type/breast/prognosis-and-survival/?region=on.