ANALYZING ANTIULCER RATIO PROTECTION OF PEPINO DULCE FRUIT JUICE (Solanum muricatum Aiton) USING MICE AS AN ANIMAL EXPERIMENTAL MODEL
Nyi Mekar Saptarini(1*), Dadan Suryasaputra(2), Atep Misbah Saepulhak(3)
(1) Faculty of Pharmacy, Universitas Padjajaran
(2) Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Al Ghifari
(3) Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Al Ghifari
(*) Corresponding Author
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Ahumada, M. and Cantwell, M. 1996. Postharvest Studies on Pepino Dulce (Solanum muricatum Ait.): Maturity at Harvest and Storage Behavior. Elsevier. Postharvest Biology and Technology 7: 129-136
Alarcon de la Lastra A.C., Martin M.J., and Motilva, V. 1995. Gastroprotection induced by silymarin, the hepatoprotective principle of Silybum marianum in ischemia-reperfusion mucosal injury: role of neutrophils. Planta Med 61 (20): 116-119
Annamalai, A.R. and Manavalan, R. 1990. Effects of Trikatu and its individual components and piperine on gastrointestinal tract: Trikatu - a bioavailable enhancer. Indian Drugs 27, 595-604
Bagchi, D., Ray, S.D., Bagchi, M., Preuss, H.G., and Stohs, S.J. 2002. Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. Indian J Exp Biol 40(6): 717-726
Bai, Y.F. and Xu, H. 2000. Protective action of piperine against experimental gastric ulser. Acta Pharmacol.Sin. 21, 357-359
Bandyopadhyay, D., Biswas, K., Bhattacharyya, M., Reiter, R.J., and Banerjee, R.K. 2001. Gastric Toxicity and Mucosal Ulseration Induced by Oxygen-Derived Reactive Species: Protection by Melatonin.Curr. Mol. Med. 1: 501-513
Cho, C.H. and Wang J.Y. 2002. Gastointestinal Mucosal Repair and Experimental Therapeutics. Frontiers of Gastrointestinal Res, Basel. Karger, 25, p 251
Cho, C.H. and Wang J.Y. 2002. Gastointestinal mucosal repair and experimental therapeutics. Frontiers of Gastrointestinal Res, Basel. Karger, p 251
Dennis, D.J., Burge, G.K. and Lill, R. 1985. Pepinos:Cultural Techniques. Information Services, Ministry of Agriculture, Wellington, N.Z., p. 2
Esaki N., Kato M., Takizawa N., Morimoyo S., Nonaka G., and Nishioca I. 1986. Pharmacological studies on Linderae umbellate Ramus. IV. Effects of condensed tannin related compounds on pepitic acitivity and stressinduced gastric lesions in mice. Planta Med 1: 34-38
Fallone, C.A. and Morris, G.P. 1995. Topical nicotine protects rat gastric mucosa against ASA-induced damage. A role for mucosal fluid secretion in cytoprotection. Digest. Dis. Sci. 40, 936-942
Goel R.K., Chakraborti A., and Sanyal A.K. 1985. The effect of biological variable on the anti ulcerogenic effect of vegetable planta in banana. Planta Med. 2: 85-88
Harman, J.E., Hogg, M. and Horne, S.F. 1986. Maturity and Quality Indices for Pepino Fruit. HortScience, 21(3): 129 (abstract)
Kaunitz, J.D. and Akiba, Y. 2004. Gastroduodenal Mucosal Defense: Role of Endogenous Mediators. Curr.Opin. Gastroenterol. 20, 526-532
Kim S.C., Byun S.H., and Yang C.H. 2004. Cytoprotective effects of Glycyrrhizae radix extract and its active component liquiritigenin against cadmium-induced toxicity (effects on bad translocation and cytochrome c-mediated PARP cleavage). Toxicology 197(3): 239-251
Konturek, P.C., Konturek, S.J., Majka, J., Zembala, M., and Hahn, E.G. 1997. Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects. Eur. J. Pharmacol. 322, 73-77
Kyogoku, K., Hatayama, K., and Yokomori, S. 1979. Anti-ulser effect of isoprenyl flavonoids. II. Synthesis and anti-ulser activity of new chalcones related to sophoradin. Chem Pharm Bull 1979; 27: 2943-2952
Liu, C.F., Lin, C.C., Lin, M.H., Lin, Y.S., and Lin, S.C. 2002. Cytoprotection by propolis ethanol extract of acute absolute ethanol-induced gastric mucosal lesions. Am J Chin Med 30(2-3): 245-254
Mills, S. and Bone, K. 2000. Principles and Practice of Phytotherapy Modern Herbal Medicine, Churchill: Livingstone, p. 161-176, 396
Omoto, T., Shinho, Y., Nakajima, K., Ishiwatari, H., and Ito, H. 1990. Antiulser alkaloids from Picrasma ailanthus. Jpn Kokai Tokyo Koho 02004790
Pastrada-Bonilla, E., Akoh, C.C., Sellappan, S., and Krewer, G. 2003. Phenolic content and antioxidant capacity of muscadine grapes. J Agric Food Chem 51(18): 5497-5503
Prohens, J., Ruiz, J.J. and Nuez, F. 2000. Growing Cycles for a New Crop, the Pepino, in the Spanish Mediterranean. Acta Horticulturae 523: 53–60
Redgwell, R.J. and Turner, N.A., 1986. Pepino (Solanum muricatum): Chemical Composition of Ripe Fruit. J. Sci. Food Agric., 37: 1217-1222
Tan, P.V., Nyasse, B., Dimo, T., Wafo, P., and Akahkuh, B.T. 2002. Synergistic and potentiating effects of ranitidine and two new anti-ulser compounds from Enantia chlorantha and Voacanga africana in experimental animal models. Pharmazie 57, 409-412
Tan, P.V.; Nyasse, B.; Enow-Orock, G.E.; Wafo, P.; Forcha, E.A. 2000. Prophylactic and healing properties of a new anti-ulser compound from Enantia chlorantha in rats. Phytomedicine 7, 291-296
Tani, S. 1976. Effect of tannic acid and taic acid atarch on the experimental gastric ulser in rats. J. Pharm. Soc. Jpn 96: 648-652
Tarnawski, A.S. 2005. Cellular and Molecular Mechanisms of Gastrointestinal Ulser Healing. Digest. Dis.Sci., 50, 24-33
Wan, Y.J. 1993. Effect of anisodamine on gastric ulser induced by restraint water-immersion in rats. Clin. Gastroenterol. 3, 154-158
Wang, J.L. 2000. Effect of anisodamine on the reserpine-induced gastric mucosal lesion in rats. Zhongguo Bingli Shengli Zazhi 16, 237-242
Weinges, K., 1967. Carbohydrate Content and Sucrose Metabolism (Phytochemistry in Developing Solanum muricatum Aiton Fruits), Tetrahedrun Letter, 737-740
Weiss, R.F. and Fintelmann, V. 2000. Herbal Medicine, Thiene Stugart: NY, 65-70
Yamahara, J., Mohizuki, M., Huang Qi Roang H., and Fuzimura. 1988. The Antiulser Effect in Rats of Ginger Constituent. Journal of Ethopharmacology, 7: 299-304
Yamazaki, M. and Shirota, H. 1981. Application of experimental stress ulser test in mice for the survey of neurotropic naturally occurring drug materials. Shoyakugaku Zasshi 35, 96-102
Yong, D.G., Geng, B.Q., Gu, G.G., Zhong, F.M., and Yu, W.H. 1991. Anti-ulser effect of anisodamine in rats. Acta Pharmacol. Sin. 12, 522-525
Zhang, J.F., Yan, C.D., Zhang, Y.Q., Gao, W.Z., and Zhai, X.M. 1990. Effect of scopolia drugs on the gastric mucosal lesion in rats. Acta Pharmacol. Sin. 25, 90-94
Zhu, Z.P., Zhang, M.F., and Shen, Y.Q. 1993. Antiulser components of Sophora viciifolia alkaloids. Tianran Chanwu Yanjiu Yu Kaifa 5, 26-29
DOI: https://doi.org/10.22146/tradmedj.8343
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