FORMULATION OF ANTIOXIDANT LOTION CONTAINING WATER EXTRACT OF GREEN TEA LEAF (Camellia sinensis L)

https://doi.org/10.22146/tradmedj.8134

Fahrauk Faramayuda(1*), Fikri Alatas(2), Yesi Desmiaty(3)

(1) Department of Pharmacy, University of Jenderal Ahmad Yani
(2) Department of Pharmacy, University of Jenderal Ahmad Yani
(3) Department of Pharmacy, University of Jenderal Ahmad Yani
(*) Corresponding Author

Abstract


The research about lotion dosage formulation that contain green tea leaf water extract with concentration 0.0002%, 0.002%, 0,02%, and 8.6% had been done. The basic of the EC50 value. Which calculated from linierity regression equation between tested solution concentration and scavenging percent. The lotion formulation began with lotion base orientation included organoleptic, homogeinity, pH, and viscosity. It showed that lotion base with glyceryl monostearate 5.5% have the best pH stability, viscosity, and consistency. Evaluation of lotion dosage include physical evaluation (organoleptic, homogeinity, viscosity and stability) and chemical evalution (pH and the stability of lotion antioxidant activity. Antioxidant activity stability evaluation of lotion with 1,1-diphenyl-2-picrylhidrazyl solution using spectrophotometri UV-Visible showed, that formula which contain 0.02% and 8.6% green tea leaf water extract gave the best radical scavenging activity and stable during storage. 


Keywords


extract, lotion, antioxidant



References

Agoes, G. dan Darijanto, S.T., 1993, Teknologi Farmasi Liquida dan Semi Solida, 73-78, 111-112, 125-127, Pusat Antar Universitas Bidang Hayati

Ansel, H.C., 1989, Pengantar Bentuk Sediaan Farmasi, edisi IV, terjemahan Farida ibrahim, UI Press, Jakarta

Dep. Kes. RI, 1979, Materia Medika Indonesia, jilid III, 159, Jakarta

Dep. Kes. RI, 1995, Farmakope Indonesia, edisi IV, 949-951, Jakarta

Dep. Kes. RI, 2001, Inventaris Tanaman Obat Indonesia (I), Badan Penelitian dan Pengembangan Kesehatan. Jilid 2

Ferdiansyah, 1999, Telaah Fitokimia dan Uji Aktivitas Antioksidan Secara In vitro Ekstrak Daging Buah Mangga (Mangifera indica Linn.), Skripsi, UNJANI, Bandung

Harper, 1995, Biokimia, 124-131, 630-641, 758-780, Penerbit Buku Kedokteran EGC, Jakarta

Jellenik, J.S., 1970, Formulation and Function of Cosmetic, 324-325, translated by G.L. Fenton, Willey, Interscience, New York

Marwali, H., 2002, Ilmu Penyakit Kulit, 1-3, Penerbit Hipokrates, Jakarta.

Mutchler, E., 1991, Dinamika Obat, Edisi V, 193-196, 577-580, terjemahan M.B Widianto dan A.S ranti penerbit ITB

Sauriasari, R., 2006, Mengenal dan Menangkal Radikal Bebas, Artikel Iptek Bidang Biologi Pangan dan Kesehatan

Sidik, 1997, Antioksidan Alami Asal Tumbuhan, 1-4, Seminar Tumbuhan Obat Indonesia XII., ITB

Sultoni, M.A., 1992, Petunjuk Kultur Teknis Tanaman Teh, Pusat Penelitian Teh dan Kina Gambung, Ciwidey, Bandung

Syah, A.N Alam, 2006, Taklukkan Penyakit Dengan Teh Hijau, 46-58, 106-112, Agromedia Pustaka, Jakarta

Tuminah, S., 2004, Teh Sebagai Salah Satu Sumber Antioksidan, Cermin Dunia Kedokteran, 144, 52

Yamamoto, Juneja, and Chu., 1997, Chemistry and Application of Green Tea, 15-17, CRC press, New York



DOI: https://doi.org/10.22146/tradmedj.8134

Article Metrics

Abstract views : 3967 | views : 45787

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2010 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada