Physical Stability and Antioxidant Activity of Pee-Off Gel Mask Ethanol Extract of Buas-buas Leaf (Premna serratifolia L.)
Weni Puspita(1*), Heny Puspasari(2)
(1) Akademi Farmasi Yarsi Pontianak, East Pontianak, West Kalimantan
(2) Akademi Farmasi Yarsi Pontianak, East Pontianak, West Kalimantan
(*) Corresponding Author
Abstract
This study aims to determine the physical stability and antioxidant activity of peel-off gel mask ethanol extract of buas-buas leaf (Premna serratifolia L.). The ethanol extract of buas-buas leaves was obtained by maceration using 70% ethanol solvent, then concentrated using a rotary evaporator to get a thick extract. Formulation EEDB into a peel-off gel mask with a concentration of each EEDB (FI: 1%, FII: 2%, FIII : 3%). The EEDB peel-off gel mask formula was tested for physical stability by cycling test method using a climatic chamber at a temperature of 40°C ± 2°C and 4°C ± 2°C for six cycles. The tests included organoleptic, homogeneity, viscosity, pH, spreadability, and drying time. An antioxidant test was carried out using the DPPH method. The results of the physical stability test on the three EEDB peel-off gel mask formulas (FI: 1%, FII: 2%, FIII: 3%) showed good physical stability because there was no significant difference during six storage cycles (P>0.05) with the results of the preparation have a characteristic aroma of oleum citri, brownish-green in color, have a thick, homogeneous texture, meet the requirements of pH, viscosity, spreadability, and drying time. The stability test results of the antioxidant activity of the peel-off gel mask EEDB in the three formulas showed no significant change (P>0.05). The antioxidant activity during six storage cycles with the highest average percent inhibition before and after the cycling test, namely in Formula III, was 77.20 ± 0.28%.
Keywords
Full Text:
PDFReferences
Barel, A. O., Paye, M., & Maibach, H. I. (2009). Handbook of Cosmetic Science and Technology. Informa Healthcare USA (3rd Ed.). New York. https://doi.org/10.1001/archderm.138.9.1262-a
Bendra, A., 2012, Uji Antioksidan dan Ekstrak Daun Premna Oblongata Miq Dengan Metode DPPH dan Identifikasi Golongan Senyawa Kimia Dari Fraksi Teraktif, Skripsi, Fakultas MIPA Universitas Indonesia, Jakarta
Beringhs, A.O., M.R. Julia, K.S. Hellen, M.B. Rosane, and S. Diva. 2013. Green clay and aloe vera peel-off facial masks: response surface methodology applied to the formulation design. AAPS Pharm Sci Tech. 14 (1): 445-455.
Brick CS, Degoutin N, Tabary V, Miri, Bacquet M. 2014. New crosslinked cast films based on poly (vinyl alcohol): Preparation and physico-chemical properties. eXPRESS Polymer Letters. 8(12): 941-952.
Dureja, H., Kaushik, D., Gupta, M., Kumar, V., dan Lather, V., 2010, Cosmeceuticals:An Emerging Concept, Indian J Pharmacol.
Febrianti, N., & Wahyuningsih, R. (2016). Uji Aktivitas Antioksidan Ekstrak Etanol Berbagai Buah Tropik dengan Metode Ferrous Ion Chelating. Prosiding Symbion, 629–634.
Hanani, E., Munim, A., & Sekarini, R. (2005). Identifikasi Senyawa Antioksidan Dalam Spons Callyspongia Sp Dari Kepulauan Seribu. Majalah Ilmu Kefarmasian, 2(3), 127–133.
Kuncari, E. S., Iskandarsyah dan Praptiwi. (2014). Evaluasi, Uji Stabilitas Fisik Dan Sineresis Sediaan Gel yang Mengandung Minoksidil, Apigenin dan Perasan Herba Seledri (Apium Graveolens L.). Bulletin Penelitian Kesehatan. 42 (4): 213-222.
Liya. 2016. Karakterisasi dan Skrining Fitokimia Daun Singkil (Premna corymbosa Rottl & Willd). (Karya Tulis Ilmiah). Samarinda: D-III Farmasi Akademi Farmasi Samarinda
Madan, J., and R. Singh, 2010, Formulation and Evaluation of Aloe vera Topical Gel. Int J.Ph.Sci. 2 (2): 551-555.
Mumtihanah, A.M., 2015, Evaluasi Stabilitas Fisik dan Profil Difusi Sediaan Gel Minyak Zaitun, Jurnal Fitofarmaka Indonesia, Vol.4 No.1, Fakultas Farmasi Universitas Muslim Indonesia, Jakarta.
Murbantan, Anwar Mustafa, Mochamad Rosjidi, H. S. (2010). Proses Ekstraksi dan Powderisasi Zat Warna Alam. Industri Kimia Kecil Dan Menengah,1–5.
Percival. (1998). Antioxidants. Clinical Nutrition Insights.
Puspita, W., Sari, D.Y, dan Rahman, I.R, 2020, Uji Aktivitas Antioksidan Ekstrak Etanol Daun Buas-buas (Premna Serratifolia L.) Asal Kabupaten Melawi Provinsi Kalimantan Barat dengan Metode DPPH. Jurnal Insan Farmasi Indonesia, 3(2) : 405-412
Rahmawanty, Dina., Nita. Yulianti, dan Mia. Fitriana, 2015, Formulasi dan Evaluasi Masker Wajah Peel-Off Mengandung Kuersetin Dengan Variasi Konsentrasi Gelatin dan Gliserin."Media Farmasi. 12 (1): 17-32.
Regina, A., Maimunah, M., & Yovita, L. (2008). Penentuan Aktivitas Antioksidan, Kadar Fenolat Total dan Likopen pada Buah Tomat (Solanum lycopersicum L). Jurnal Sains Dan Teknologi Farmasi, 13(1).
Sihombing, L.N.B., dan Lestari P.C., 2015, Formulasi dan evaluasi sediaan spray gel lidah buaya (Aloe Vera L.) dengan variasi Konsentrasi Carbomer dan HPMC, Jurnal Farmasi, Jurusan Farmasi Politeknik Kesehatan Kementrian Kesehatan, Bandung.
Suhartono, E. (2016). Toksisitas Oksigen Reaktif dan Antioksidan Di Bidang Kedokteran dan Kesehatan. Yogyakarta: Gosyen Publishing.
Suryani., Putri, A.E.P, Agustyiani, P. 2017. Formulasi dan Uji Stabilitas Sediaan Gel Ekstrak Terpurifikasi Daun Paliasa (Kleinhovia Hospita L.) yang Berefek Antioksidan. PHARMACON 6 (3): 157-169.
Sutriningsih., dan Astuti, I. W., 2017, Uji Antioksidan dan Formulasi Sediaan Masker Peel-Off dari Ekstrak Biji Alpukat (Persea americana Mill.) dengan Perbedaan Konsentrasi PVA (Polivinil Alkohol), Skripsi, Universitas 17 Agustus 1945, Jakarta.
Syarifah, R. S., Mulyanti, D., & Gadri, A. (2015). Formulasi Sediaan Masker Gel Peel-Off Ekstrak Daun Pepaya (Carica Papaya L.) sebagai Antijerawat dan Uji Aktivitasnya terhadap Bakteri Propionibacterium Acnes. Prosiding Penelitian SPeSIA Unisba 2015, 662–670.
Tranggono, Retno Iswari, Latifah, Fatmah. 2007. Buku pegangan ilmu pengetahuan kosmetik. Jakarta (ID): PT. Gramedia Pustaka.
Voigt R. Buku Pelajaran Teknologi Farmasi, diterjemahkan oleh Soewandhi SS, Mathilda B, Widianto. Yogyakarta: Gadjah Mada University Press. 1995
DOI: https://doi.org/10.22146/mot.71033
Article Metrics
Abstract views : 1890 | views : 1767Refbacks
- There are currently no refbacks.
Copyright (c) 2022 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada