Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process
Kintoko Kintoko(1*), Hanifah Karimatulhajj(2), Trie Yuni Elfasyari(3), Ersi Arviana Ihsan(4), Teguh Adiyas Putra(5), Puspawan Hariadi(6), Citra Ariani(7), Nurkhasanah Nurkhasanah(8)
(1) Faculty of Pharmacy, Ahmad Dahlan University, Yogyakarta
(2) Graduate Program of Pharmacy, Ahmad Dahlan University, Yogyakarta
(3) Graduate Program of Pharmacy, Ahmad Dahlan University, Yogyakarta
(4) Graduate Program of Pharmacy, Ahmad Dahlan University, Yogyakarta
(5) Graduate Program of Pharmacy, Ahmad Dahlan University, Yogyakarta
(6) Faculty of Pharmacy, Ahmad Dahlan University, Yogyakarta
(7) Faculty of Pharmacy, Ahmad Dahlan University, Yogyakarta
(8) Faculty of Pharmacy, Ahmad Dahlan University, Yogyakarta
(*) Corresponding Author
Abstract
Keywords
Full Text:
PDFReferences
Anonim. 2014. Laporan Hasil Riset Kesehatan Dasar Indonesia (Riskesdas). 2013. Di Akses Di Http://http://www. Litbang. Depkes. Go. Id/sites/download/materi_pertemuan/ launch_ riskesdas/Riskesdas 20.
Ariani, S. 2014. Khasiat Daun Binahong (Anredera cordifolia (Ten.) Steenis) terhadap Pembentukan Jaringan Granulasi dan Reepitelisasi Penyembuhan Luka Terbuka Kulit Kelinci. Jurnal E-Biomedik 1.
Ekaviantiwi, T. A. 2013. Identifikasi Asam Fenolat dari Ekstrak Etanol Daun Binahong (Anredera cordifolia (Ten.) Stennis) dan Uji Aktivitas Antioksidan. Chem Info Journal 1(1): 283–293.
Enoch, S. and Leaper, D.J. 2008. Basic science of wound healing. Surgery (Oxford). 26: 31–37.
Furman, B. L., 2015, Streptozotocin-induced diabetic models in mice and rats, Current Protocols in Pharmacology. 5–47.
Ghasemi, A., Khalifi, S. and Jedi, S. 2014. Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review). Acta Physiologica Hungarica. 101: 408–420.
Ghosh, P.K. and Gaba, A. 2013. Phyto-extracts in wound healing. Journal of Pharmacy & Pharmaceutical Sciences. 16: 760–820.
Hartoyo, A., Muchtadi, D., Astawan, M., Dahrulsyah and Winarto, A. 2011. Pengaruh Ekstrak Protein Kacang Komak (Lablab purpureus (L.) Sweet) pada Kadar Glukosa dan Profil Lipida Serum Tikus Diabetes. J. Teknol. Dan Industri Pangan XXII.
Islas-Andrade, S., Monsalve, M. C. R., de la Peña, J. E., Polanco, A. C., Palomino, M. A. & Velasco, A. F. 2001. Streptozotocin and alloxan in experimental diabetes: comparison of the two models in rats. Acta Histochemica et Cytochemica. 33(3): 201–208.
Jeffcoate, W.J. and Harding, K.G. 2003. Diabetic foot ulcers. The Lancet. 361: 1545–1551.
Karri, V.N.R., Kuppusamy, G., Mulukutla, S., Sood, S. and Malayandi, R. 2015. Understanding the implications of pharmaceutical excipients and additives in the treatment of diabetic foot ulcers. Journal of Excipients and Food Chemicals. 6: 7–22.
Kintoko & Desmayanti, A. 2016. The effectivity of ethanolic extract of binahong leaves (Anredera cordifolia (tenore) steen) gel in the management of diabetic wound healing in aloxan-induced rat models. Jurnal Kedokteran Dan Kesehatan Indonesia. 7(5): 227–236.
Kolluru, G. K., Bir, S. C. & Kevil, C. G. 2012. Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. International Journal of Vascular Medicine 2012.
Leung, P.C. 2007. Diabetic foot ulcers—a comprehensive review. The Surgeon. 5: 219–231.
Mappa, T., Edy, H.J. and Kojong, N. 2013. Formulasi Gel Ekstrak Daun Sasaladahan (Peperomia pellucida (L.) HBK) dan Uji Efektivitasnya Terhadap Luka Bakar pada Kelinci (Oryctolagus Cuniculus). Pharmacon 2.
Morton, J.J. and Malone, M.H. 1972. Evaluation of vulneray activity by an open wound procedure in rats. Archives Internationales de Pharmacodynamie et de Therapie. 196: 117–126.
Muruganandan, S., Srinivasan, K., Gupta, S., Gupta, P.K. and Lal, J. 2005. Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats. Journal of Ethnopharmacology. 97: 497–501.
Nagori, B.P. and Solanki, R. 2011. Role of medicinal plants in wound healing. Research Journal of Medicinal Plant. 5: 392–405.
Najafi, S. 2013. Phytochemical screening and antibacterial activity of leaf extract of Ziziphus mauritiana Lam. International Research Journal of Applied and Basic Sciences. 4: 3274–3276.
Nayak, B. Shivananda, Pereira, L. P. & Maharaj, D. 2007. Wound healing activity of Carica papaya L. in experimentally induced diabetic rats. Indian Journal of Experimental Biology. 45(8): 739.
Patel, D. K., Kumar, R., Laloo, D. & Hemalatha, S. 2012. Diabetes mellitus: an overview on its pharmacological aspects and reported medicinal plants having antidiabetic activity. Asian Pacific Journal of Tropical Biomedicine. 2(5): 411–420.
Rini, S. 2012. Pengaruh pemberian diet tinggi lemak terhadap kadar trigliserida pada tikus. PhD. Thesis, Universitas Muhammadiyah Surakarta.
Romero-Cerecero, O., Zamilpa, A., Díaz-García, E.R. and Tortoriello, J. 2014. Pharmacological effect of Ageratina pichinchensis on wound healing in diabetic rats and genotoxicity evaluation. Journal of Ethnopharmacology. 156: 222–227.
Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K.M. and Latha, L.Y. 2011. Extraction, isolation and characterization of bioactive compounds from plants’ extracts. African Journal of Traditional, Complementary and Alternative Medicines 8.
Shukla, A., Rasik, A. M., Jain, G. K., Shankar, R., Kulshrestha, D. K. & Dhawan, B. N. 1999. In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica, Journal of Ethnopharmacology. 65(1): 1–11.
Srinivasan, K., Viswanad, B., Asrat, L., Kaul, C.L. and Ramarao, P. 2005. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacological Research. 52: 313–320.
Sutrisno, E., I, K.A., Sukandar, E.Y., Fidrianny, I. and Aligita, W. 2016. Anti-Inflammatory Study of Anredera Cordifolia Leaves and Centella Asiatica Herbs and Its Combinations Using Human Red Blood Cell-Membrane Stabilization Method. Asian Journal of Pharmaceutical and Clinical Research. 0: 78–80.
Takahashi, M., Asikin, Y., Takara, K. and Wada, K. 2012. Screening of medicinal and edible plants in Okinawa, Japan, for enhanced proliferative and collagen synthesis activities in NB1RGB human skin fibroblast cells. Bioscience, Biotechnology, and Biochemistry. 76: 2317–2320.
Vidinskỳ, B., Gál, P., Toporcer, T., Longauer, F., Lenhardt, L., Bobrov, N. et al. 2006. Histological study of the first seven days of skin wound healing in rats. Acta Veterinaria Brno. 75(2): 197–202.
Wang, H., Li, H., Jiang, X., Shi, W., Shen, Z. and Li, M. 2014. Hepcidin Is Directly Regulated by Insulin and Plays an Important Role in Iron Overload in Streptozotocin-Induced Diabetic Rats. Diabetes. 63(5): 1506–1518.
Zychowska, M., Rojewska, E., Przewlocka, B. and Mika, J. 2013. Mechanisms and pharmacology of diabetic neuropathy–experimental and clinical studies. Pharmacological Reports. 65: 1601–1610.
DOI: https://doi.org/10.22146/tradmedj.27921
Article Metrics
Abstract views : 7390 | views : 16436Refbacks
- There are currently no refbacks.
Copyright (c) 2017 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada